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1,3-dipropyl-8-cyclopentylxanthine and Tremor

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Tremor in 2 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"Tremulous jaw movements in rats, which can be induced by dopamine (DA) antagonists, DA depletion, and cholinomimetics, have served as a useful model for studies of tremor."7.76Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX. ( Brennum, LT; Chrobak, JJ; Collins, LE; Galtieri, DJ; Hinman, JR; Hockemeyer, J; Müller, CE; Sager, TN; Salamone, JD, 2010)
"Tremulous jaw movements in rats, which can be induced by dopamine (DA) antagonists, DA depletion, and cholinomimetics, have served as a useful model for studies of tremor."3.76Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX. ( Brennum, LT; Chrobak, JJ; Collins, LE; Galtieri, DJ; Hinman, JR; Hockemeyer, J; Müller, CE; Sager, TN; Salamone, JD, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Collins, LE1
Galtieri, DJ1
Brennum, LT1
Sager, TN1
Hockemeyer, J1
Müller, CE1
Hinman, JR1
Chrobak, JJ1
Salamone, JD1
Concas, A1
Mascia, MP1
Cuccheddu, T1
Floris, S1
Mostallino, MC1
Perra, C1
Satta, S1
Biggio, G1

Other Studies

2 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Tremor

ArticleYear
Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 94, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Disease Models, Anima

2010
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:2

    Topics: Adenosine; Alcoholism; Animals; Cerebellar Cortex; Cerebellum; Dose-Response Relationship, Drug; Eth

1996