1,3-dipropyl-8-cyclopentylxanthine has been researched along with Substance Withdrawal Syndrome in 7 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of different doses of adenosine receptor agonists and antagonists on naloxone-induced jumping and diarrhea in morphine-dependent mice were studied." | 3.70 | Effects of adenosine receptor agents on the expression of morphine withdrawal in mice. ( Naghipour, B; Roushan-zamir, F; Shafaghi, B; Zarrindast, MR, 1999) |
| "Adenosine A1 receptors were not desensitized, because the potency of the metabolically stable adenosine analog N6-cyclopentyl-adenosine was unchanged after chronic cocaine withdrawal." | 1.30 | Decreased presynaptic sensitivity to adenosine after cocaine withdrawal. ( Bockaert, J; Manzoni, O; Pujalte, D; Williams, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hack, SP | 1 |
| Vaughan, CW | 1 |
| Christie, MJ | 1 |
| Bailey, A | 1 |
| Gianotti, R | 1 |
| Ho, A | 1 |
| Kreek, MJ | 1 |
| Butler, TR | 1 |
| Smith, KJ | 1 |
| Self, RL | 1 |
| Braden, BB | 1 |
| Prendergast, MA | 1 |
| Concas, A | 1 |
| Mascia, MP | 1 |
| Cuccheddu, T | 1 |
| Floris, S | 1 |
| Mostallino, MC | 1 |
| Perra, C | 1 |
| Satta, S | 1 |
| Biggio, G | 1 |
| Manzoni, O | 1 |
| Pujalte, D | 1 |
| Williams, J | 1 |
| Bockaert, J | 1 |
| Zarrindast, MR | 1 |
| Naghipour, B | 1 |
| Roushan-zamir, F | 1 |
| Shafaghi, B | 1 |
| Coupar, IM | 1 |
| Tran, BL | 1 |
7 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Re | 2003 |
Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose "binge" cocaine-treated rats.
Topics: Adenosine; Analgesics, Opioid; Animals; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Coc | 2005 |
Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Cell Survival | 2008 |
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
Topics: Adenosine; Alcoholism; Animals; Cerebellar Cortex; Cerebellum; Dose-Response Relationship, Drug; Eth | 1996 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyri | 1998 |
Effects of adenosine receptor agents on the expression of morphine withdrawal in mice.
Topics: Adenosine; Analysis of Variance; Animals; Behavior, Animal; Diarrhea; Male; Mice; Mice, Inbred Strai | 1999 |
Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Female; Injections, Subcuta | 2001 |