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1,3-dipropyl-8-cyclopentylxanthine and Status Epilepticus

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Status Epilepticus in 2 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
"Adenosine has powerful inhibitory effects in the central nervous system."5.32Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy. ( Avsar, E; Empson, RM, 2004)
" The purposes of this study were to characterize the role of adenosine receptors in modulating status epilepticus (SE) induced by pilocarpine and evaluate its neuroprotective action."3.73Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats. ( Cavalheiro, EA; da Silva Fernandes, MJ; DonĂ¡, F; Ferreira, AT; Vianna, EP, 2005)
"Adenosine has powerful inhibitory effects in the central nervous system."1.32Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy. ( Avsar, E; Empson, RM, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avsar, E1
Empson, RM1
Vianna, EP1
Ferreira, AT1
DonĂ¡, F1
Cavalheiro, EA1
da Silva Fernandes, MJ1

Other Studies

2 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Status Epilepticus

ArticleYear
Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy.
    Neuropharmacology, 2004, Volume: 47, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Analysis of Variance; Animals;

2004
Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats.
    Epilepsia, 2005, Volume: 46 Suppl 5

    Topics: 5'-Nucleotidase; Adenosine; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe;

2005