1,3-dipropyl-8-cyclopentylxanthine has been researched along with Spinal Cord Injuries in 5 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since theophylline has two modes of action, in the present study we tested whether chronic administration of pentoxifylline, a non-selective phosphodiesterase inhibitor, rolipram, a phosphodiesterase-4 specific inhibitor, and 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), an adenosine A1 receptor antagonist, would induce recovery similar to that induced by theophylline in male Sprague-Dawley rats following a left C2 spinal cord lesion." | 1.35 | Administration of phosphodiesterase inhibitors and an adenosine A1 receptor antagonist induces phrenic nerve recovery in high cervical spinal cord injured rats. ( Goshgarian, HG; Kajana, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, X | 1 |
| Hassan, MM | 1 |
| Ghosh, S | 1 |
| Mao, G | 2 |
| Sankari, A | 1 |
| Minic, Z | 1 |
| Zhang, Y | 1 |
| Goshgarian, HG | 3 |
| Nantwi, KD | 2 |
| James, E | 1 |
| Kajana, S | 1 |
5 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Spinal Cord Injuries
| Article | Year |
|---|---|
Efficacy and toxicity of the DPCPX nanoconjugate drug study for the treatment of spinal cord injury in rats.
Topics: Animals; Diaphragm; Male; Nanoconjugates; Rats; Recovery of Function; Spinal Cord Injuries; Xanthine | 2022 |
Transporter Protein-Coupled DPCPX Nanoconjugates Induce Diaphragmatic Recovery after SCI by Blocking Adenosine A1 Receptors.
Topics: Adenosine A1 Receptor Antagonists; Animals; Diaphragm; Male; Muscle Strength; Nanoconjugates; Rats; | 2016 |
Actions of specific adenosine receptor A1 and A2 agonists and antagonists in recovery of phrenic motor output following upper cervical spinal cord injury in adult rats.
Topics: Adenosine; Animals; Cervical Vertebrae; Female; Phenethylamines; Phrenic Nerve; Purinergic P1 Recept | 2002 |
Involvement of peripheral adenosine A2 receptors in adenosine A1 receptor-mediated recovery of respiratory motor function after upper cervical spinal cord hemisection.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2006 |
Administration of phosphodiesterase inhibitors and an adenosine A1 receptor antagonist induces phrenic nerve recovery in high cervical spinal cord injured rats.
Topics: Action Potentials; Animals; Cervical Vertebrae; Diaphragm; Disease Models, Animal; Electromyography; | 2008 |