1,3-dipropyl-8-cyclopentylxanthine has been researched along with Pregnancy in 15 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have investigated how CHU affects cardiovascular responses evoked by acute systemic hypoxia in adult male offspring, recognising that adenosine contributes to hypoxia-induced muscle vasodilatation and bradycardia by acting on A(1) receptors in normal (N) rats." | 7.76 | Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors. ( Coney, AM; Marshall, JM, 2010) |
| "The status of the adenosine A1 receptor/adenylyl cyclase (A1R/AC) transduction pathway in rat brain was analysed at the end of pregnancy using different approaches." | 7.72 | Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy. ( Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA, 2004) |
| " We have investigated how CHU affects cardiovascular responses evoked by acute systemic hypoxia in adult male offspring, recognising that adenosine contributes to hypoxia-induced muscle vasodilatation and bradycardia by acting on A(1) receptors in normal (N) rats." | 3.76 | Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors. ( Coney, AM; Marshall, JM, 2010) |
| "The status of the adenosine A1 receptor/adenylyl cyclase (A1R/AC) transduction pathway in rat brain was analysed at the end of pregnancy using different approaches." | 3.72 | Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy. ( Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA, 2004) |
| "Pregnant rats were treated daily with 1 g/L of caffeine or theophylline in their drinking water during pregnancy and the effect of these methylxanthines on adenosine A1 receptor was assayed using binding and reverse transcription polymerase chain reaction (RT-PCR) assays in brains from both mothers and full-term fetuses." | 3.71 | Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats. ( Albasanz, JL; Fernández, M; León, D; Martín, M; Ruíz, MA, 2002) |
| "In caffeine group, an increase in the baseline Rf in presence of the pons and no change in medullary-spinal cord preparations have been observed." | 1.32 | Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats. ( Bodineau, L; Frugière, A; Gaytan, S; Gros, F; Saadani-Makki, F, 2004) |
| "Caffeine treatment had no significant effect on adenosine A1 receptors or on A1 receptor mRNA." | 1.31 | Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain. ( Adén, U; Fredholm, BB; Herlenius, E; Tang, LQ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Alves, CB | 1 |
| Almeida, AS | 1 |
| Marques, DM | 1 |
| Faé, AHL | 1 |
| Machado, ACL | 1 |
| Oliveira, DL | 1 |
| Portela, LVC | 1 |
| Porciúncula, LO | 1 |
| Maeda, T | 3 |
| Koos, BJ | 3 |
| Jensen, EC | 1 |
| Bennet, L | 1 |
| Fraser, M | 1 |
| Power, GG | 1 |
| Hunter, CJ | 1 |
| Gunn, AJ | 1 |
| Coney, AM | 1 |
| Marshall, JM | 1 |
| León, D | 3 |
| Albasanz, JL | 3 |
| Ruíz, MA | 2 |
| Fernández, M | 2 |
| Martín, M | 3 |
| Saadani-Makki, F | 1 |
| Frugière, A | 1 |
| Gros, F | 1 |
| Gaytan, S | 1 |
| Bodineau, L | 1 |
| Donoso, MV | 1 |
| López, R | 1 |
| Miranda, R | 1 |
| Briones, R | 1 |
| Huidobro-Toro, JP | 1 |
| Castillo, CA | 1 |
| Lillrank, SM | 1 |
| Lipska, BK | 1 |
| Weinberger, DR | 1 |
| Fredholm, BB | 2 |
| Fuxe, K | 1 |
| Ferré, S | 1 |
| Adén, U | 1 |
| Herlenius, E | 1 |
| Tang, LQ | 1 |
| Jan, C | 1 |
| Lopez, G | 1 |
| Schiemann, WP | 2 |
| Westfall, DP | 1 |
| Buxton, IL | 2 |
| Walther, JM | 1 |
15 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Pregnancy
| Article | Year |
|---|---|
Caffeine and adenosine A
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Animals; Attention Deficit Disord | 2020 |
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Blood Gas | 2009 |
Adenosine A(1) receptor mediated suppression of adrenal activity in near-term fetal sheep.
Topics: Adenosine A1 Receptor Antagonists; Adrenocorticotropic Hormone; Animals; Asphyxia; Carbon Dioxide; F | 2010 |
Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bradycardia; Endothelium, Vascular; Female; H | 2010 |
Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats.
Topics: Animals; Binding, Competitive; Brain; Caffeine; Down-Regulation; Female; Gestational Age; Pregnancy; | 2002 |
Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.
Topics: Adenosine; Adenylyl Cyclases; Aldehyde-Lyases; Animals; Antihypertensive Agents; Binding Sites; Blot | 2004 |
Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats.
Topics: Adenosine; Animals; Animals, Newborn; Caffeine; Female; In Vitro Techniques; Medulla Oblongata; Neur | 2004 |
A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Arachidonic Acid; C | 2005 |
Effect of glutamate intake during gestation on adenosine A(1) receptor/adenylyl cyclase pathway in both maternal and fetal rat brain.
Topics: Adenosine A1 Receptor Antagonists; Adenylyl Cyclases; Animals; Brain; Dose-Response Relationship, Dr | 2008 |
Adenosine and dopamine receptor antagonist binding in the rat ventral and dorsal striatum: lack of changes after a neonatal bilateral lesion of the ventral hippocampus.
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Benzazepines; Corpus Striatum; Disease Models, Anim | 1999 |
Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain.
Topics: Adenosine; Animals; Animals, Newborn; Autoradiography; Brain; Caffeine; Female; Gene Expression Regu | 2000 |
Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Female; Fetal Hypoxia; Heart Rate; Hydrogen- | 2001 |
Adenosine A(2A) receptors mediate hypoxic inhibition of fetal breathing in sheep.
Topics: Animals; Carbon Dioxide; Electroencephalography; Electrooculography; Eye Movements; Female; Fetal Bl | 2002 |
Smooth muscle adenosine A1 receptors couple to disparate effectors by distinct G proteins in pregnant myometrium.
Topics: Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Female; | 1991 |
On the ability of endogenous adenosine to regulate purine nucleoside receptor binding of antagonists in smooth muscle membranes.
Topics: Adenosine; Animals; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; | 1990 |