1,3-dipropyl-8-cyclopentylxanthine has been researched along with Myocardial Infarction in 19 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cardioprotective effects of the selective adenosine A1-receptor agonist, GR79236 (N-[(1S, trans)-2-hydroxycyclopentyl]adenosine), were examined in a porcine model of myocardial ischaemia-reperfusion injury." | 7.70 | The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig. ( Drew, GM; Hunt, AA; Louttit, JB; Maxwell, MP, 1999) |
| " To address this concern, the present study was designed to compare the actions of the A(1)AR antagonists CPX (1,3-dipropyl-8-cyclopentylxanthine), BG 9719 (1,3-dipropyl-8-[2-(5,6-epoxynorbornyl)]xanthine), and BG 9928 (1,3-dipropyl-8-[1-(4-propionate)-bicyclo-[2,2,2]octyl]xanthine) on acute myocardial ischemia/reperfusion injury and ischemic preconditioning (IPC) in an in vivo dog model of infarction." | 3.72 | Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs. ( Auchampach, JA; Ge, ZD; Gross, GJ; Jin, X; Kiesman, W; Kreckler, LM; Moore, J; Narayanan, J; Smits, G; Ticho, B; Wan, TC; Whalley, E, 2004) |
| "The cardioprotective effects of the selective adenosine A1-receptor agonist, GR79236 (N-[(1S, trans)-2-hydroxycyclopentyl]adenosine), were examined in a porcine model of myocardial ischaemia-reperfusion injury." | 3.70 | The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig. ( Drew, GM; Hunt, AA; Louttit, JB; Maxwell, MP, 1999) |
| "Acute myocardial infarction was induced by occlusion of the left coronary artery for 1 h followed by reperfusion for 24 h." | 1.29 | Role of endogenous endothelin in the extension of myocardial infarct size studied with the endothelin receptor antagonist, TAK-044. ( Fujino, M; Fujiwara, S; Kojima, M; Kusumoto, K; Watanabe, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gross, GJ | 4 |
| Hsu, A | 1 |
| Gross, ER | 1 |
| Falck, JR | 1 |
| Nithipatikom, K | 1 |
| Kehl, F | 1 |
| Krolikowski, JG | 1 |
| LaDisa, JF | 1 |
| Kersten, JR | 1 |
| Warltier, DC | 1 |
| Pagel, PS | 1 |
| Auchampach, JA | 2 |
| Jin, X | 1 |
| Moore, J | 1 |
| Wan, TC | 1 |
| Kreckler, LM | 1 |
| Ge, ZD | 1 |
| Narayanan, J | 1 |
| Whalley, E | 1 |
| Kiesman, W | 1 |
| Ticho, B | 1 |
| Smits, G | 1 |
| Reid, EA | 1 |
| Kristo, G | 1 |
| Yoshimura, Y | 1 |
| Ballard-Croft, C | 1 |
| Keith, BJ | 1 |
| Mentzer, RM | 2 |
| Lasley, RD | 2 |
| Kin, H | 1 |
| Zatta, AJ | 1 |
| Lofye, MT | 1 |
| Amerson, BS | 1 |
| Halkos, ME | 1 |
| Kerendi, F | 1 |
| Zhao, ZQ | 1 |
| Guyton, RA | 1 |
| Headrick, JP | 2 |
| Vinten-Johansen, J | 1 |
| Solenkova, NV | 1 |
| Solodushko, V | 1 |
| Cohen, MV | 2 |
| Downey, JM | 3 |
| Philipp, S | 1 |
| Yang, XM | 1 |
| Cui, L | 1 |
| Davis, AM | 1 |
| Donato, M | 1 |
| D'Annunzio, V | 1 |
| Berg, G | 1 |
| Gonzalez, G | 1 |
| Schreier, L | 1 |
| Morales, C | 1 |
| Wikinski, RL | 1 |
| Gelpi, RJ | 1 |
| Armstrong, S | 1 |
| Ganote, CE | 1 |
| Liu, GS | 1 |
| Richards, SC | 1 |
| Olsson, RA | 1 |
| Mullane, K | 1 |
| Walsh, RS | 1 |
| Kojima, M | 1 |
| Kusumoto, K | 1 |
| Fujiwara, S | 1 |
| Watanabe, T | 1 |
| Fujino, M | 1 |
| Noble, MA | 1 |
| Konyn, PJ | 1 |
| Neely, CF | 1 |
| DiPierro, FV | 1 |
| Kong, M | 1 |
| Greelish, JP | 1 |
| Gardner, TJ | 1 |
| Mei, DA | 1 |
| Sleph, PG | 1 |
| Grover, GJ | 1 |
| Louttit, JB | 2 |
| Hunt, AA | 1 |
| Maxwell, MP | 1 |
| Drew, GM | 2 |
| Sheldrick, A | 1 |
| Gray, KM | 1 |
| Morrison, RR | 1 |
| Jones, R | 1 |
| Byford, AM | 1 |
| Stell, AR | 1 |
| Peart, J | 1 |
| Matherne, GP | 1 |
| McCully, JD | 1 |
| Toyoda, Y | 1 |
| Uematsu, M | 1 |
| Stewart, RD | 1 |
| Levitsky, S | 1 |
19 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Myocardial Infarction
| Article | Year |
|---|---|
Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Capsaicin; Cytochrome P-450 Enzyme System; Hemodynamics; Ische | 2013 |
Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs.
Topics: Administration, Oral; Animals; Collateral Circulation; Coronary Circulation; Disease Models, Animal; | 2003 |
Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs.
Topics: Adenosine A1 Receptor Antagonists; Anesthesia; Animals; Disease Models, Animal; Dogs; Ischemic Preco | 2004 |
In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.
Topics: Animals; Butadienes; Enzyme Inhibitors; Imidazoles; Ischemic Preconditioning, Myocardial; MAP Kinase | 2005 |
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Puri | 2005 |
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
Topics: Acetamides; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Androstadienes; An | 2006 |
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Alkaloi | 2006 |
Ischemic postconditioning reduces infarct size by activation of A1 receptors and K+(ATP) channels in both normal and hypercholesterolemic rabbits.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary C | 2007 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocar | 1994 |
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarctio | 1994 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; D | 1993 |
Role of endogenous endothelin in the extension of myocardial infarct size studied with the endothelin receptor antagonist, TAK-044.
Topics: Animals; Dogs; Endothelin Receptor Antagonists; Endothelins; Glyburide; Male; Myocardial Infarction; | 1995 |
Different effects of an adenosine A1 analogue and ischemic preconditioning in isolated rabbit hearts.
Topics: Animals; Coronary Circulation; In Vitro Techniques; Myocardial Infarction; Myocardial Reperfusion In | 1995 |
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the heart.
Topics: Animals; Arrhythmias, Cardiac; Cats; Hemodynamics; Myocardial Infarction; Myocardial Ischemia; Myoca | 1996 |
Adenosine A1 receptor blockade does not abolish the cardioprotective effects of the adenosine triphosphate-sensitive potassium channel opener bimakalim.
Topics: Animals; Benzopyrans; Cardiotonic Agents; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; | 1997 |
The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Coronary Disease; Female; Heart Rate; Male; Molecula | 1999 |
The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Body Temperature; Heart Rate; Ischemic Preconditioni | 1999 |
Transgenic overexpression of cardiac A(1) adenosine receptors mimics ischemic preconditioning.
Topics: Animals; Blood Flow Velocity; Cell Survival; Coloring Agents; Coronary Circulation; In Vitro Techniq | 2000 |
Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion.
Topics: Adenosine; Animals; Dihydropyridines; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Myo | 2001 |