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1,3-dipropyl-8-cyclopentylxanthine and Muscle Contraction

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Muscle Contraction in 36 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Colitis was induced by 2,4-dinitrobenzenesulfonic acid."7.77Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis. ( Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N; Tuccori, M, 2011)
" Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks."7.71Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001)
"Pretreatment with adenosine receptor antagonists, theophylline or 8-cyclopentyl-1,3-dipropyl xanthine (DPCPX) prior to ischemic preconditioning or adenosine preconditioning abolished the protective effects of preconditioning by ischemic preconditioning and adenosine preconditioning."5.34Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors. ( Demiryürek, AT; Gümüşel, B; Lippton, H; Yildiz, G, 2007)
" Colitis was induced by 2,4-dinitrobenzenesulfonic acid."3.77Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis. ( Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N; Tuccori, M, 2011)
" Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks."3.71Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia. ( Hamann, M; Richter, A, 2001)
"Recently, there has been an increasing interest in adenosine as a potential mediator of allergic asthma."3.69Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor. ( Ali, S; Metzger, WJ; Mustafa, SJ, 1994)
"The role of adenosine in regulating glycogen breakdown during electrically induced muscle contractions was investigated in isolated rat hindquarters perfused with a standard medium either lacking or containing 100 microU/ml insulin and/or 1."3.69Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle. ( Hespel, P; Richter, EA; Vergauwen, L, 1997)
"Pretreatment with adenosine receptor antagonists, theophylline or 8-cyclopentyl-1,3-dipropyl xanthine (DPCPX) prior to ischemic preconditioning or adenosine preconditioning abolished the protective effects of preconditioning by ischemic preconditioning and adenosine preconditioning."1.34Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors. ( Demiryürek, AT; Gümüşel, B; Lippton, H; Yildiz, G, 2007)
" AP(4)A dose-response curve was to the left of that of ATP, and maximum response was greater than that produced by ATP."1.34Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide. ( Al-Hrasen, MN; El-Hadiyah, TM; Khattab, MM, 2007)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (50.00)18.2507
2000's15 (41.67)29.6817
2010's3 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bornia, EC1
Bando, E1
Machinski, M1
Pereira, MW1
Alves-Do-Prado, W1
Antonioli, L1
Fornai, M1
Colucci, R1
Awwad, O1
Ghisu, N1
Tuccori, M1
Del Tacca, M1
Blandizzi, C1
Yang, J1
Ip, PS1
Yeung, JH1
Che, CT1
Aronsson, P1
Johnsson, M1
Vesela, R1
Winder, M1
Tobin, G1
Thong, FS1
Graham, TE1
Storr, M1
Thammer, J1
Dunkel, R1
Schusdziarra, V1
Allescher, HD1
Diniz, C1
Leal, S1
Gonçalves, J1
Jankowski, M1
Szczepańska-Konkel, K1
Kalinowski, L1
Angielski, S1
Zizzo, MG1
Mulè, F1
Serio, R1
Alexander, SP1
Yildiz, G1
Demiryürek, AT1
Gümüşel, B1
Lippton, H1
Khattab, MM1
Al-Hrasen, MN1
El-Hadiyah, TM1
Sundqvist, M1
Ozacmak, VH1
Sayan, H1
Prentice, DJ1
Shankley, NP1
Black, JW1
Reeves, JJ1
Jarvis, JE1
Sheehan, MJ1
Strong, P1
Vergauwen, L2
Hespel, P2
Richter, EA2
Ali, S1
Mustafa, SJ1
Metzger, WJ1
Muller, MJ1
Prior, T1
Hunt, RH1
Rangachari, PK1
Palea, S1
Corsi, M1
Pietra, C1
Artibani, W1
Calpista, A1
Gaviraghi, G1
Trist, DG1
Hourani, SM3
Nicholls, J1
Lee, BS1
Halfhide, EJ1
Kitchen, I3
Abiru, T1
Endo, K1
Machida, H1
Brownhill, VR1
Oka, M1
Kimura, Y1
Itoh, Y1
Sasaki, Y1
Taniguchi, N1
Ukai, Y1
Yoshikuni, Y1
Kimura, K1
Malinowski, MN1
Cannady, SB1
Schmit, KV1
Barr, PM1
Schrock, JW1
Wilson, DF1
Lagente, V1
Barlinski, J1
Cano, E1
Frossard, N1
Han, DH1
Hansen, PA1
Nolte, LA1
Holloszy, JO1
Hong, SJ1
Chang, CC1
Peachey, JA1
Yang, SJ1
An, JY1
Shim, JO1
Park, CH1
Huh, IH1
Sohn, UD1
Lee, JJ1
Talubmook, C1
Parsons, ME1
Coupar, IM1
Tran, BL1
Richter, A1
Hamann, M1
Nagano, O1
Földes, FF1
Nakatsuka, H1
Reich, D1
Ohta, Y1
Sperlagh, B1
Vizi, ES1
Cascalheira, JF1
Sebastião, AM1

Reviews

1 review available for 1,3-dipropyl-8-cyclopentylxanthine and Muscle Contraction

ArticleYear
The putative roles of adenosine in insulin- and exercise-mediated regulation of glucose transport and glycogen metabolism in skeletal muscle.
    Canadian journal of applied physiology = Revue canadienne de physiologie appliquee, 2002, Volume: 27, Issue:2

    Topics: Adenosine; Animals; Diabetes Mellitus; Exercise; Glucose; Glucose Transporter Type 4; Glycogen; GTP-

2002

Other Studies

35 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Muscle Contraction

ArticleYear
Presynaptic M1, M2, and A1 receptors play roles in tetanic fade induced by pancuronium or cisatracurium.
    Journal of anesthesia, 2009, Volume: 23, Issue:4

    Topics: Animals; Atracurium; Diamines; Electric Stimulation; Hexamethonium; In Vitro Techniques; Male; Musca

2009
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adeno

2011
Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Aug-15, Volume: 18, Issue:11

    Topics: Adrenergic Antagonists; Animals; Atropine; Benzyl Compounds; Colon, Ascending; Cyclic GMP; Cycloocta

2011
Adenosine receptor antagonism suppresses functional and histological inflammatory changes in the rat urinary bladder.
    Autonomic neuroscience : basic & clinical, 2012, Nov-02, Volume: 171, Issue:1-2

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cyclophosphamide; Cystitis; Dose-Response Rel

2012
Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum.
    BMC neuroscience, 2002, Dec-20, Volume: 3

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Flavins; Gastrointestina

2002
Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
    European journal of pharmacology, 2003, Jan-24, Volume: 460, Issue:2-3

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Epididymis; Immunohis

2003
Involvement of Rho-kinase in P2Y-receptor-mediated contraction of renal glomeruli.
    Biochemical and biophysical research communications, 2003, Mar-21, Volume: 302, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Glomerular Mesangiu

2003
Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
    British journal of pharmacology, 2006, Volume: 148, Issue:7

    Topics: Adenosine; Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; Mice, In

2006
Flavonoids as antagonists at A1 adenosine receptors.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:11

    Topics: Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Elect

2006
Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors.
    European journal of pharmacology, 2007, Feb-05, Volume: 556, Issue:1-3

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Ischemic Preconditioning; Lung; Male; Malondi

2007
Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide.
    Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; In Vitr

2007
Developmental changes of purinergic control of intestinal motor activity during metamorphosis in the African clawed frog, Xenopus laevis.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 292, Issue:5

    Topics: Adenosine Triphosphate; Animals; Enzyme Inhibitors; Intestines; Metamorphosis, Biological; Molecular

2007
Pretreatment with adenosine and adenosine A1 receptor agonist protects against intestinal ischemia-reperfusion injury in rat.
    World journal of gastroenterology, 2007, Jan-28, Volume: 13, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Glutathione; Ileum; Intestines; Male; Muscle Con

2007
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Do

1995
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
    British journal of pharmacology, 1995, Volume: 114, Issue:5

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Te

1995
Adenosine receptors mediate synergistic stimulation of glucose uptake and transport by insulin and by contractions in rat skeletal muscle.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:3

    Topics: Animals; Biological Transport; Caffeine; Cyclic AMP; Glucose; Insulin; Male; Muscle Contraction; Mus

1994
Adenosine-induced bronchoconstriction and contraction of airway smooth muscle from allergic rabbits with late-phase airway obstruction: evidence for an inducible adenosine A1 receptor.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Adenosine; Animals; Asthma; Binding, Competitive; Bronchoconstriction; Disease Models, Animal; In Vi

1994
Adenosine A1 receptors are not involved in contraction of canine gastric muscularis mucosae by adenosine analogues.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Drug Interactions; F

1994
ADP beta S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1

    Topics: 4-Chloromercuribenzenesulfonate; Adenosine Diphosphate; Adenosine Triphosphate; Humans; In Vitro Tec

1994
Characterization and ontogeny of P1-purinoceptors on rat vas deferens.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Animals, Newbo

1993
Differential vasodilatory action of 2-octynyladenosine (YT-146), an adenosine A2 receptor agonist, in the isolated rat femoral artery and vein.
    European journal of pharmacology, 1995, Jul-25, Volume: 281, Issue:1

    Topics: Adenosine; Alkynes; Animals; Endothelium, Vascular; Femoral Artery; Femoral Vein; Male; Muscle Contr

1995
Selective enhancement by an adenosine A1 receptor agonist of agents inducing contraction of the rat vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Bradykinin; Carbachol; Dos

1996
Brain pertussis toxin-sensitive G proteins are involved in the flavoxate hydrochloride-induced suppression of the micturition reflex in rats.
    Brain research, 1996, Jul-15, Volume: 727, Issue:1-2

    Topics: Animals; Brain; Cyclic AMP; Female; Flavoxate; GTP-Binding Proteins; Muscle Contraction; Muscle, Smo

1996
Adenosine exerts a glycogen-sparing action in contracting rat skeletal muscle.
    The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 1

    Topics: Adenosine; Animals; Caffeine; Cyclic AMP; Drug Combinations; Glycogen; Glycogen Synthase; Male; Musc

1997
Adenosine depresses transmitter release but is not the basis for 'tetanic fade' at the neuromuscular junction of the rat.
    Neuroscience letters, 1997, Jul-18, Volume: 230, Issue:2

    Topics: Adenosine; Animals; Diaphragm; Electric Stimulation; Feedback; Female; In Vitro Techniques; Motor En

1997
Adenosine reduces airway excitatory non-cholinergic (e-NC) contraction through both A1 and A2 adenosine receptor activation in the guinea pig.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:6

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bronchi; Cholinergic Fibers; Dipyridamole; Do

1997
Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions.
    Diabetes, 1998, Volume: 47, Issue:11

    Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Biological Transport; Cyclic A

1998
Evaluation of intrinsic modulation of synaptic transmission by ATP in mouse fast twitch muscle.
    Journal of neurophysiology, 1998, Volume: 80, Issue:5

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Diaphragm; Drug Antagonism; In Vitro Techniques; Mem

1998
Ontogeny of adenosine receptors in the longitudinal muscle and muscularis mucosae of the rat distal colon.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aging; Animals; Autoradiography; Binding Sites; Bindin

1999
The mechanism of contraction by 2-chloroadenosine in cat detrusor muscle cells.
    The Journal of urology, 2000, Volume: 163, Issue:2

    Topics: 2-Chloroadenosine; Animals; Cats; Chloromercuribenzoates; GTP-Binding Proteins; Muscle Contraction;

2000
Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum.
    Journal of autonomic pharmacology, 2001, Volume: 21, Issue:1

    Topics: Acetylcholine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cho

2001
Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.
    Life sciences, 2001, Jul-06, Volume: 69, Issue:7

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Female; Injections, Subcuta

2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug;

2001
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:2

    Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm;

1992
Adenine nucleotide analogues, including gamma-phosphate-substituted analogues, are metabolised extracellularly in innervated frog sartorius muscle.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, High Pr

1992