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1,3-dipropyl-8-cyclopentylxanthine and Memory Disorders

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Memory Disorders in 7 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.

Research Excerpts

ExcerptRelevanceReference
" In this study, we addressed whether the chronic administration of 8-cyclopentyl-1,3-dipropylxanthine, a potent and selective adenosine A1 antagonist, could reverse the memory deficits found in aged APPswe/PS1dE9 mice."1.39Chronic treatment with DCPCX, an adenosine A(1) antagonist, worsens long-term memory. ( Bond, RA; Eriksen, JL; Forkuo, GS; Vollert, C, 2013)
" Chronic administration did not cause any effect on memory, but decreased adenosine A(1) receptors immunocontent in the frontal cortex."1.37Blockade of adenosine A(1) receptors prevents methylphenidate-induced impairment of object recognition task in adult mice. ( Ardais, AP; Botton, PH; Costa, MS; Espinosa, J; Matte, VL; Mioranzza, S; Porciúncula, LO; Souza, DO, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oliveira, SLB1
Oliveira, MGM1
Hipolide, DC1
Vollert, C1
Forkuo, GS1
Bond, RA1
Eriksen, JL1
Pagnussat, N1
Almeida, AS1
Marques, DM1
Nunes, F1
Chenet, GC1
Botton, PH2
Mioranzza, S2
Loss, CM1
Cunha, RA3
Porciúncula, LO2
Cognato, GP1
Agostinho, PM2
Hockemeyer, J1
Müller, CE1
Souza, DO2
Costa, MS1
Ardais, AP1
Matte, VL1
Espinosa, J1
Costenla, AR1
Diógenes, MJ1
Canas, PM1
Rodrigues, RJ1
Nogueira, C1
Maroco, J1
Ribeiro, JA1
de Mendonça, A1
Prediger, RD1
Fernandes, D1
Takahashi, RN1

Other Studies

7 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Memory Disorders

ArticleYear
A
    Neurobiology of learning and memory, 2019, Volume: 160

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Avoidance Learning; Behavior, Animal; Conditi

2019
Chronic treatment with DCPCX, an adenosine A(1) antagonist, worsens long-term memory.
    Neuroscience letters, 2013, Aug-26, Volume: 548

    Topics: Adenosine A1 Receptor Antagonists; Alzheimer Disease; Animals; Memory Disorders; Memory, Long-Term;

2013
Adenosine A(2A) receptors are necessary and sufficient to trigger memory impairment in adult mice.
    British journal of pharmacology, 2015, Volume: 172, Issue:15

    Topics: Adenosine; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Infusions, Intraventricula

2015
Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.
    Journal of neurochemistry, 2010, Volume: 112, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Animals, Newborn; Caffeine; Diseas

2010
Blockade of adenosine A(1) receptors prevents methylphenidate-induced impairment of object recognition task in adult mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jan-15, Volume: 35, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Central Nervous System Stimulants;

2011
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.
    The European journal of neuroscience, 2011, Volume: 34, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aging; Animals; Ele

2011
Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.
    Behavioural brain research, 2005, Apr-30, Volume: 159, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Caffeine; Discrimination Learning;

2005