1,3-dipropyl-8-cyclopentylxanthine has been researched along with Ischemia in 9 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used adenosine A1 receptor agonist N6-1(phenyl-2R-isopropyl)-adenosine (PIA), A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), and ATP-sensitive K+ (KATP) channel blockers sodium 5-hydroxydecanoate (5-HD) and glibenclamide (Glib), as probes to investigate the role and mechanism of adenosine in ischemic preconditioning (IPC) of noncontractile skeletal muscle against infarction, using the pig latissimus dorsi muscle flap model." | 7.69 | Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction. ( Forrest, CR; He, W; Neligan, P; Pang, CY; Xu, H; Zhong, A, 1997) |
| "We used adenosine A1 receptor agonist N6-1(phenyl-2R-isopropyl)-adenosine (PIA), A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), and ATP-sensitive K+ (KATP) channel blockers sodium 5-hydroxydecanoate (5-HD) and glibenclamide (Glib), as probes to investigate the role and mechanism of adenosine in ischemic preconditioning (IPC) of noncontractile skeletal muscle against infarction, using the pig latissimus dorsi muscle flap model." | 3.69 | Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction. ( Forrest, CR; He, W; Neligan, P; Pang, CY; Xu, H; Zhong, A, 1997) |
| "Brief ischemia was reported to protect various cells against injury induced by subsequent ischemia-reperfusion, and this phenomenon is known as ischemic preconditioning." | 1.32 | Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina. ( Ishii, K; Kuwagata, M; Nakahara, T; Saito, M; Sakamoto, K; Yonoki, Y, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moosavi, SM | 1 |
| Bayat, G | 1 |
| Owji, SM | 1 |
| Panjehshahin, MR | 1 |
| Sakamoto, K | 1 |
| Yonoki, Y | 1 |
| Kuwagata, M | 1 |
| Saito, M | 1 |
| Nakahara, T | 1 |
| Ishii, K | 1 |
| Wirkner, K | 1 |
| Köfalvi, A | 1 |
| Fischer, W | 1 |
| Günther, A | 1 |
| Franke, H | 1 |
| Gröger-Arndt, H | 1 |
| Nörenberg, W | 1 |
| Madarász, E | 1 |
| Vizi, ES | 2 |
| Schneider, D | 1 |
| Sperlágh, B | 2 |
| Illes, P | 2 |
| Zsilla, G | 1 |
| Baranyi, M | 1 |
| Neely, CF | 1 |
| Keith, IM | 1 |
| Pang, CY | 1 |
| Neligan, P | 1 |
| Zhong, A | 1 |
| He, W | 1 |
| Xu, H | 1 |
| Forrest, CR | 1 |
| Davis, JM | 1 |
| Gute, DC | 1 |
| Jones, S | 1 |
| Krsmanovic, A | 1 |
| Korthuis, RJ | 1 |
| Rego, AC | 1 |
| Agostinho, P | 1 |
| Melo, J | 1 |
| Cunha, RA | 1 |
| Oliveira, CR | 1 |
| Sugino, H | 1 |
| Shimada, H | 1 |
| Tsuchimoto, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Single-blinded Placebo-controlled Trial of Ischemic Preconditioning in Raynaud's Phenomenon (RP)[NCT02506062] | 21 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Ischemia
| Article | Year |
|---|---|
Early renal post-ischaemic tissue damage and dysfunction with contribution of A1-adenosine receptor activation in rat.
Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Ischemia; Kidney; Male; Microscopy, | 2009 |
Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina.
Topics: Adrenergic alpha-Antagonists; Animals; Enzyme Inhibitors; Intraocular Pressure; Ischemia; Ischemic P | 2004 |
Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Anestheti | 2005 |
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.
Topics: Adenosine; Adenosine Triphosphate; Analgesics; Animals; Dose-Response Relationship, Drug; Glucose; G | 2007 |
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the lung.
Topics: Animals; Cats; Erythrocytes; Infusions, Intra-Arterial; Ischemia; Lung; Lung Transplantation; Macrop | 1995 |
Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction.
Topics: Adenosine; Animals; Decanoic Acids; Glyburide; Hydroxy Acids; Infarction; Ischemia; Ischemic Precond | 1997 |
Ischemic preconditioning prevents postischemic P-selectin expression in the rat small intestine.
Topics: Adenosine; Adenosine Deaminase; Animals; Antibodies, Monoclonal; Ischemia; Ischemic Preconditioning; | 1999 |
Adenosine A2A receptors regulate the extracellular accumulation of excitatory amino acids upon metabolic dysfunction in chick cultured retinal cells.
Topics: Adenosine; Analysis of Variance; Animals; Aspartic Acid; Bicuculline; Cells, Cultured; Chick Embryo; | 2000 |
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preco | 2001 |