1,3-dipropyl-8-cyclopentylxanthine has been researched along with Injury, Myocardial Reperfusion in 24 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To address this concern, the present study was designed to compare the actions of the A(1)AR antagonists CPX (1,3-dipropyl-8-cyclopentylxanthine), BG 9719 (1,3-dipropyl-8-[2-(5,6-epoxynorbornyl)]xanthine), and BG 9928 (1,3-dipropyl-8-[1-(4-propionate)-bicyclo-[2,2,2]octyl]xanthine) on acute myocardial ischemia/reperfusion injury and ischemic preconditioning (IPC) in an in vivo dog model of infarction." | 3.72 | Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs. ( Auchampach, JA; Ge, ZD; Gross, GJ; Jin, X; Kiesman, W; Kreckler, LM; Moore, J; Narayanan, J; Smits, G; Ticho, B; Wan, TC; Whalley, E, 2004) |
| "Adenosine (100 microM) was administered to these neurons via their local arterial blood supply during or immediately after transient coronary artery occlusion." | 1.32 | Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system. ( Armour, JA; Arora, RC, 2003) |
| "Isoflurane was administered for 30 min before and during LAD occlusions and reperfusions and was discontinued at the onset of final reperfusion." | 1.30 | Role of adenosine in isoflurane-induced cardioprotection. ( Gross, GJ; Kersten, JR; Mei, DA; Orth, KG; Pagel, PS; Warltier, DC, 1997) |
| "The incidence of arrhythmias observed upon restoration of control flow was increased by ISO when the action of endogenous adenosine was blocked with DPCPX." | 1.29 | Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion. ( Dobson, JG; Fenton, RA; Galeckas, KJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (45.83) | 18.2507 |
| 2000's | 11 (45.83) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urmaliya, VB | 1 |
| Pouton, CW | 2 |
| Ledent, C | 1 |
| Short, JL | 1 |
| White, PJ | 1 |
| Abd-Elfattah, AS | 1 |
| Ding, M | 1 |
| Jessen, ME | 1 |
| Wechsler, AS | 1 |
| Arora, RC | 1 |
| Armour, JA | 1 |
| Auchampach, JA | 1 |
| Jin, X | 1 |
| Moore, J | 1 |
| Wan, TC | 1 |
| Kreckler, LM | 1 |
| Ge, ZD | 1 |
| Narayanan, J | 1 |
| Whalley, E | 1 |
| Kiesman, W | 1 |
| Ticho, B | 1 |
| Smits, G | 1 |
| Gross, GJ | 4 |
| Philipp, S | 1 |
| Yang, XM | 1 |
| Cui, L | 1 |
| Davis, AM | 1 |
| Downey, JM | 1 |
| Cohen, MV | 1 |
| Lu, J | 1 |
| Zang, WJ | 1 |
| Yu, XJ | 1 |
| Jia, B | 1 |
| Chorvatova, A | 1 |
| Sun, L | 1 |
| Reichelt, ME | 1 |
| Willems, L | 2 |
| Peart, JN | 1 |
| Ashton, KJ | 1 |
| Matherne, GP | 1 |
| Blackburn, MR | 1 |
| Headrick, JP | 3 |
| Donato, M | 1 |
| D'Annunzio, V | 1 |
| Berg, G | 1 |
| Gonzalez, G | 1 |
| Schreier, L | 1 |
| Morales, C | 1 |
| Wikinski, RL | 1 |
| Gelpi, RJ | 1 |
| Gregg, A | 1 |
| Bottle, SE | 1 |
| Devine, SM | 1 |
| Figler, H | 1 |
| Linden, J | 1 |
| White, P | 1 |
| Urmaliya, V | 1 |
| Scammells, PJ | 1 |
| Armstrong, S | 1 |
| Ganote, CE | 1 |
| Raschke, P | 2 |
| Becker, BF | 2 |
| Schwartz, LM | 1 |
| Gerlach, E | 1 |
| Yao, Z | 1 |
| Fenton, RA | 1 |
| Galeckas, KJ | 1 |
| Dobson, JG | 1 |
| Lasley, RD | 1 |
| Noble, MA | 1 |
| Konyn, PJ | 1 |
| Mentzer, RM | 1 |
| Neely, CF | 1 |
| DiPierro, FV | 1 |
| Kong, M | 1 |
| Greelish, JP | 1 |
| Gardner, TJ | 1 |
| Mei, DA | 2 |
| Sleph, PG | 1 |
| Grover, GJ | 1 |
| Wang, J | 1 |
| Drake, L | 1 |
| Sajjadi, F | 1 |
| Firestein, GS | 1 |
| Mullane, KM | 1 |
| Bullough, DA | 1 |
| Kersten, JR | 1 |
| Orth, KG | 1 |
| Pagel, PS | 1 |
| Warltier, DC | 1 |
| Sheldrick, A | 1 |
| Gray, KM | 1 |
| Drew, GM | 1 |
| Louttit, JB | 1 |
| Forman, MB | 1 |
| Vitola, JV | 1 |
| Velasco, CE | 1 |
| Murray, JJ | 1 |
| Dubey, RK | 1 |
| Jackson, EK | 1 |
| McCully, JD | 1 |
| Toyoda, Y | 1 |
| Uematsu, M | 1 |
| Stewart, RD | 1 |
| Levitsky, S | 1 |
| Harrison, GJ | 1 |
| Cerniway, RJ | 1 |
| Peart, J | 1 |
| Berr, SS | 1 |
| Ashton, K | 1 |
| Regan, S | 1 |
| Paul Matherne, G | 1 |
| Flood, AJ | 1 |
24 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.
Topics: Acetamides; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine | 2010 |
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction | 2012 |
Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system.
Topics: Adenosine; Animals; Female; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Recepto | 2003 |
Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs.
Topics: Adenosine A1 Receptor Antagonists; Anesthesia; Animals; Disease Models, Animal; Dogs; Ischemic Preco | 2004 |
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.
Topics: Acetamides; Adenosine; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Alkaloi | 2006 |
Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Cell Hypoxia; Cell Shape; Cells, Cultured; | 2006 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; | 2007 |
Ischemic postconditioning reduces infarct size by activation of A1 receptors and K+(ATP) channels in both normal and hypercholesterolemic rabbits.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary C | 2007 |
Dual acting antioxidant A1 adenosine receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Antioxidants; Binding Sites; Cardiotonic Agents; | 2007 |
In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: effects of selective adenosine receptor blockade and calphostin C.
Topics: Animals; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Naphth | 1995 |
Adenosine and PAF dependent mechanisms lead to myocardial reperfusion injury by neutrophils after brief ischaemia.
Topics: Adenosine; Animals; Azepines; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion | 1995 |
Adenosine contributes to neutrophil-mediated loss of myocardial function in post-ischemic guinea-pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Flow Velocity; Cardiac Output; Coronary Circulation; | 1993 |
Glibenclamide antagonizes adenosine A1 receptor-mediated cardioprotection in stunned canine myocardium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dogs; Female; Glyburide; Male; Myocardial Contraction; M | 1993 |
Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Coronary Circulation; Epinephrin | 1995 |
Different effects of an adenosine A1 analogue and ischemic preconditioning in isolated rabbit hearts.
Topics: Animals; Coronary Circulation; In Vitro Techniques; Myocardial Infarction; Myocardial Reperfusion In | 1995 |
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the heart.
Topics: Animals; Arrhythmias, Cardiac; Cats; Hemodynamics; Myocardial Infarction; Myocardial Ischemia; Myoca | 1996 |
Adenosine A1 receptor blockade does not abolish the cardioprotective effects of the adenosine triphosphate-sensitive potassium channel opener bimakalim.
Topics: Animals; Benzopyrans; Cardiotonic Agents; Coronary Circulation; Dihydropyridines; Dogs; Heart Rate; | 1997 |
Dual activation of adenosine A1 and A3 receptors mediates preconditioning of isolated cardiac myocytes.
Topics: Animals; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Myocardium; Poly | 1997 |
Role of adenosine in isoflurane-induced cardioprotection.
Topics: Anesthetics, Inhalation; Animals; Dogs; Hemodynamics; Isoflurane; Myocardial Reperfusion Injury; Pur | 1997 |
The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Body Temperature; Heart Rate; Ischemic Preconditioni | 1999 |
Sustained reduction in myocardial reperfusion injury with an adenosine receptor antagonist: possible role of the neutrophil chemoattractant response.
Topics: Animals; Coronary Circulation; Dogs; Female; Male; Myocardial Reperfusion Injury; N-Formylmethionine | 2000 |
Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion.
Topics: Adenosine; Animals; Dihydropyridines; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Myo | 2001 |
Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart.
Topics: Adenosine; Amino Acids; Animals; Creatine; Heart Rate; Hydrogen-Ion Concentration; Magnetic Resonanc | 2002 |
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; | 2002 |