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1,3-dipropyl-8-cyclopentylxanthine and Inflammation

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Inflammation in 10 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" We hypothesize that asthmatic inflammation translates into systemic inflammation and alters vascular responses where adenosine (AD) plays an important role."7.74Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma. ( Mustafa, SJ; Nadeem, A; Ponnoth, DS, 2008)
" Adenosine levels in sites of inflammation were shown to increase and exhibit immunoregulatory effects."7.73Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation. ( Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M, 2006)
" We hypothesize that asthmatic inflammation translates into systemic inflammation and alters vascular responses where adenosine (AD) plays an important role."3.74Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma. ( Mustafa, SJ; Nadeem, A; Ponnoth, DS, 2008)
" Adenosine levels in sites of inflammation were shown to increase and exhibit immunoregulatory effects."3.73Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation. ( Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Xie, AX1
Madayag, A1
Minton, SK1
McCarthy, KD1
Malykhina, AP1
Joya, A1
Ardaya, M1
Montilla, A1
Garbizu, M1
Plaza-García, S1
Gómez-Vallejo, V1
Padro, D1
Gutiérrez, JJ1
Rios, X1
Ramos-Cabrer, P1
Cossío, U1
Pulagam, KR1
Higuchi, M1
Domercq, M1
Cavaliere, F1
Matute, C1
Llop, J1
Martín, A1
Lima, FO1
Souza, GR1
Verri, WA1
Parada, CA1
Ferreira, SH1
Cunha, FQ1
Cunha, TM1
Lee, HT1
Jan, M1
Bae, SC1
Joo, JD1
Goubaeva, FR1
Yang, J1
Kim, M1
Vuckovic, S1
Tomic, M1
Stepanovic-Petrovic, R1
Ugresic, N1
Prostran, M1
Boskovic, B1
Rogachev, B1
Ziv, NY1
Mazar, J1
Nakav, S1
Chaimovitz, C1
Zlotnik, M1
Douvdevani, A1
Ponnoth, DS1
Nadeem, A1
Mustafa, SJ1
Cronstein, BN1
Naime, D1
Ostad, E1
Salvatore, CA1
Tilley, SL1
Latour, AM1
Fletcher, DS1
Koller, BH1
Jacobson, MA1

Other Studies

10 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation.
    Scientific reports, 2020, 08-25, Volume: 10, Issue:1

    Topics: Animals; Benzilates; Clozapine; Freund's Adjuvant; Genes, Synthetic; GTP-Binding Protein alpha Subun

2020
    Theranostics, 2021, Volume: 11, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Animals; Brain; Dideoxynucleosides; Immunohistochemistry; Infarct

2021
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway.
    Pain, 2010, Volume: 151, Issue:2

    Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Carrageenan; Cyclic GMP; Cyclic GM

2010
A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6

    Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Cells, Cultured; Contras

2006
Peripheral antinociception by carbamazepine in an inflammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine?
    Journal of pharmacological sciences, 2006, Volume: 100, Issue:4

    Topics: Analgesics; Animals; Caffeine; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response

2006
Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
    Kidney international, 2006, Volume: 70, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Ant

2006
Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5

    Topics: Acetylcholine; Adenosine; Administration, Inhalation; Allergens; Ambrosia; Animals; Aorta; Asthma; D

2008
The antiinflammatory effects of methotrexate are mediated by adenosine.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflamma

1994
Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells.
    The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6

    Topics: Adenosine; Animals; beta-N-Acetylhexosaminidases; Blood Pressure; Gene Targeting; Heart Rate; Inflam

2000