1,3-dipropyl-8-cyclopentylxanthine has been researched along with Cardiac Failure in 4 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " β2-adrenergic, M2-muscarinic and A1-adenosine receptors) that are responsible for these abnormalities in heart failure by chronically administrating mice a selective antagonist of each receptor (ICI118,551, atropine and 8-cyclopentyl-1,3-dipropilxanthine (DPCPX), respectively) with isoproterenol." | 3.80 | β(2)-Adrenergic and M(2)-muscarinic receptors decrease basal t-tubular L-type Ca2+ channel activity and suppress ventricular contractility in heart failure. ( Gomi, S; Hirose, M; Hongo, M; Kashihara, T; Nakada, T; Shimojo, H; Yamada, M, 2014) |
| "Cl and milrinone at A1 adenosine receptors and m-cholinoceptors were evaluated in human myocardium from patients with heart failure." | 3.68 | Antagonism of novel inotropic agents at A1 adenosine receptors and m-cholinoceptors in human myocardium. ( Böhm, M; Erdmann, E; Schwinger, RH; Ungerer, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Long, VP | 1 |
| Bonilla, IM | 1 |
| Baine, S | 1 |
| Glynn, P | 1 |
| Kumar, S | 1 |
| Schober, K | 1 |
| Mowrey, K | 1 |
| Weiss, R | 2 |
| Lee, NY | 1 |
| Mohler, PJ | 2 |
| Györke, S | 2 |
| Hund, TJ | 1 |
| Fedorov, VV | 2 |
| Carnes, CA | 2 |
| Kashihara, T | 1 |
| Hirose, M | 1 |
| Shimojo, H | 1 |
| Nakada, T | 1 |
| Gomi, S | 1 |
| Hongo, M | 1 |
| Yamada, M | 1 |
| Lou, Q | 1 |
| Hansen, BJ | 1 |
| Fedorenko, O | 1 |
| Csepe, TA | 1 |
| Kalyanasundaram, A | 1 |
| Li, N | 1 |
| Hage, LT | 1 |
| Glukhov, AV | 1 |
| Billman, GE | 1 |
| Biesiadecki, BJ | 1 |
| Ungerer, M | 1 |
| Böhm, M | 1 |
| Schwinger, RH | 1 |
| Erdmann, E | 1 |
4 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Cardiac Failure
| Article | Year |
|---|---|
Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated I
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Ani | 2020 |
β(2)-Adrenergic and M(2)-muscarinic receptors decrease basal t-tubular L-type Ca2+ channel activity and suppress ventricular contractility in heart failure.
Topics: Adenosine A1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Calcium Channels, | 2014 |
Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Topics: Action Potentials; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Atrial Fibrillation; Brady | 2014 |
Antagonism of novel inotropic agents at A1 adenosine receptors and m-cholinoceptors in human myocardium.
Topics: Adult; Binding, Competitive; Cardiotonic Agents; Electric Stimulation; Guanylyl Imidodiphosphate; He | 1990 |