1,3-dipropyl-8-cyclopentylxanthine has been researched along with Bronchial Hyperreactivity in 4 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 7.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
| "Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics." | 3.73 | A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. ( Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obiefuna, PC | 1 |
| Batra, VK | 1 |
| Nadeem, A | 1 |
| Borron, P | 1 |
| Wilson, CN | 1 |
| Mustafa, SJ | 1 |
| Smith, N | 1 |
| Broadley, KJ | 1 |
| Gu, Q | 1 |
| Ruan, T | 1 |
| Hong, JL | 1 |
| Burki, N | 1 |
| Lee, LY | 1 |
| Nieri, P | 1 |
| Lazzeri, N | 1 |
| Greco, R | 1 |
| Breschi, MC | 1 |
4 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hype | 2005 |
Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.
Topics: Adenosine Monophosphate; Administration, Inhalation; Animals; Anti-Inflammatory Agents; Asthma; Bron | 2008 |
Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Body Weight; Bradycardia; Bronchial Hyperreactivity; Capsaicin; Dose | 2003 |
Different bronchial responsiveness to Ach between normal and OA-sensitized guinea pigs after acoustic stress: a role for adenosine.
Topics: Acetylcholine; Acoustic Stimulation; Adenosine; Animals; Bronchi; Bronchial Hyperreactivity; Guinea | 1998 |