1,3-dipropyl-8-cyclopentylxanthine has been researched along with Brain Injuries in 3 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In addition, demyelination and axonal damage in brainstem were exacerbated, levels of Th1 cytokines increased, and Th2 cytokines decreased." | 1.38 | Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis. ( Augusto, E; Chen, JF; He, JC; Huang, QY; Li, F; Li, ZZ; Wang, XT; Wang, ZW; Yao, SQ; Zheng, RY, 2012) |
| "Adenosine is an endogenous neuroprotectant via anti-excitotoxic effects at A(1) receptors, and blood flow promoting and anti-inflammatory effects at A(2a) receptors." | 1.31 | Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. ( Clark, RS; Dixon, CE; Griffith, RP; Jackson, EK; Jenkins, LW; Kochanek, PM; Melick, JA; Peters, GW; Vagni, VA; Varma, MR, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz, F | 1 |
| Gutiérrez, R | 1 |
| Yao, SQ | 1 |
| Li, ZZ | 1 |
| Huang, QY | 1 |
| Li, F | 1 |
| Wang, ZW | 1 |
| Augusto, E | 1 |
| He, JC | 1 |
| Wang, XT | 1 |
| Chen, JF | 1 |
| Zheng, RY | 1 |
| Varma, MR | 1 |
| Dixon, CE | 1 |
| Jackson, EK | 1 |
| Peters, GW | 1 |
| Melick, JA | 1 |
| Griffith, RP | 1 |
| Vagni, VA | 1 |
| Clark, RS | 1 |
| Jenkins, LW | 1 |
| Kochanek, PM | 1 |
3 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Brain Injuries
| Article | Year |
|---|---|
Entorhinal cortex lesions result in adenosine-sensitive high frequency oscillations in the hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biological Clocks; Brain Injuries; Brain Wave | 2015 |
Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis.
Topics: Adenosine A1 Receptor Antagonists; Animals; Astrocytes; Axons; Brain Injuries; Cell Proliferation; C | 2012 |
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; M | 2002 |