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1,3-dipropyl-8-cyclopentylxanthine and Blood Pressure, High

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Blood Pressure, High in 5 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Research Excerpts

ExcerptRelevanceReference
" In vivo, the induction of arterial hypertension by either acute (single subcutaneous injection) or chronic (osmotic minipump for 72 hours) application of phenylephrine significantly reduced plasma renin concentration (PRC) in wild-type mice to approximately 40% of control, whereas it did not significantly affect PRC in A1AR(-/-) mice."3.73Blood pressure-dependent inhibition of Renin secretion requires A1 adenosine receptors. ( Castrop, H; Kurtz, A; Schnermann, J; Schweda, F; Segerer, F, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrettiero, DC1
Almeida, RS1
Fior-Chadi, DR1
Schweda, F1
Segerer, F1
Castrop, H1
Schnermann, J1
Kurtz, A1
Matias, A1
Zimmer, FJ1
Lorenzen, A1
Keil, R1
Schwabe, U1
Krstew, E1
Jarrott, B1
Lawrence, AJ1
Kost, CK1
Herzer, WA1
Rominski, BR1
Mi, Z1
Jackson, EK1

Other Studies

5 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Blood Pressure, High

ArticleYear
Adenosine modulates alpha2-adrenergic receptors within specific subnuclei of the nucleus tractus solitarius in normotensive and spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:12

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Dose-Response Relatio

2008
Blood pressure-dependent inhibition of Renin secretion requires A1 adenosine receptors.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Animals; Blood Pressure; Female; Hypertension; In Vitro Technique

2005
Affinity of central adenosine A1 receptors is decreased in spontaneously hypertensive rats.
    European journal of pharmacology, 1993, Feb-15, Volume: 244, Issue:3

    Topics: Adenosine; Animals; Binding, Competitive; Brain; Female; GTP-Binding Proteins; Guanosine Triphosphat

1993
Autoradiographic visualisation of axonal transport of adenosine A1 receptors along the rat vagus nerve and characterisation of adenosine A1 receptor binding in the dorsal vagal complex of hypertensive and normotensive rats.
    Brain research, 1998, Aug-17, Volume: 802, Issue:1-2

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Axonal Transport; Binding, C

1998
Diuretic response to adenosine A(1) receptor blockade in normotensive and spontaneously hypertensive rats: role of pertussis toxin-sensitive G-proteins.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: Animals; Blood Pressure; Diuresis; Drug Interactions; Furosemide; GTP-Binding Proteins; Hypertension

2000