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1,3-dipropyl-8-cyclopentylxanthine and Anochlesia

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Anochlesia in 4 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Research Excerpts

ExcerptRelevanceReference
" In addition, this series of compounds has demonstrated good bioavailability and in vivo efficacy in a rodent model of Parkinson's disease, despite having reduced potency for the rat A2A receptor versus the human A2A receptor."1.35Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy. ( Castro-Palomino, JC; Chen, Y; Crespo, MI; Díaz, JL; Gross, RS; Gual, S; Joswig, T; Lanier, MC; Lechner, SM; Lin, E; Malany, S; Markison, S; Moorjani, M; O'Brien, Z; Prat, M; Rueter, JK; Santos, M; Saunders, J; Slee, DH; Wen, J; Williams, JP; Zhang, X, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slee, DH1
Zhang, X1
Moorjani, M1
Lin, E1
Lanier, MC1
Chen, Y1
Rueter, JK1
Lechner, SM1
Markison, S1
Malany, S1
Joswig, T1
Santos, M1
Gross, RS1
Williams, JP1
Castro-Palomino, JC1
Crespo, MI1
Prat, M1
Gual, S1
Díaz, JL1
Wen, J1
O'Brien, Z1
Saunders, J1
Varty, GB1
Hodgson, RA1
Pond, AJ1
Grzelak, ME1
Parker, EM1
Hunter, JC1
Stasi, MA1
Borsini, F1
Varani, K1
Vincenzi, F1
Di Cesare, MA1
Minetti, P1
Ghirardi, O1
Carminati, P1
Mandhane, SN1
Chopde, CT1
Ghosh, AK1

Other Studies

4 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Anochlesia

ArticleYear
Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Acetamides; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Catalepsy; Cell Line;

2008
The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.
    Psychopharmacology, 2008, Volume: 200, Issue:3

    Topics: Adenosine A2 Receptor Antagonists; Animals; Antipsychotic Agents; Caffeine; Catalepsy; Cebus; Corpus

2008
ST 1535: a preferential A2A adenosine receptor antagonist.
    The international journal of neuropsychopharmacology, 2006, Volume: 9, Issue:5

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Catalepsy; CHO Cells; Criceti

2006
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
    European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3

    Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antago

1997