1,3-dipropyl-8-cyclopentylxanthine has been researched along with Anesthesia in 12 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cardioprotective effects of the selective adenosine A1-receptor agonist, GR79236 (N-[(1S, trans)-2-hydroxycyclopentyl]adenosine), were examined in a porcine model of myocardial ischaemia-reperfusion injury." | 7.70 | The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig. ( Drew, GM; Hunt, AA; Louttit, JB; Maxwell, MP, 1999) |
| "Inhaled adenosine induces airway obstruction in asthmatic but not healthy subjects, a phenomenon that is also observed in various animal species when they are immunised to a relevant antigen, but which does not occur in naïve animals." | 3.73 | Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. ( Boswell-Smith, V; Keir, S; Page, C; Spina, D, 2006) |
| " To address this concern, the present study was designed to compare the actions of the A(1)AR antagonists CPX (1,3-dipropyl-8-cyclopentylxanthine), BG 9719 (1,3-dipropyl-8-[2-(5,6-epoxynorbornyl)]xanthine), and BG 9928 (1,3-dipropyl-8-[1-(4-propionate)-bicyclo-[2,2,2]octyl]xanthine) on acute myocardial ischemia/reperfusion injury and ischemic preconditioning (IPC) in an in vivo dog model of infarction." | 3.72 | Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs. ( Auchampach, JA; Ge, ZD; Gross, GJ; Jin, X; Kiesman, W; Kreckler, LM; Moore, J; Narayanan, J; Smits, G; Ticho, B; Wan, TC; Whalley, E, 2004) |
| "Adenosine antagonists were found to be effective in improving hypotension, QRS prolongation and survival time in our rat model of amitriptyline toxicity." | 3.72 | Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? ( Akgun, A; Aygoren, O; Gidener, S; Guven, H; Kalkan, S; Tuncok, Y, 2004) |
| "The cardioprotective effects of the selective adenosine A1-receptor agonist, GR79236 (N-[(1S, trans)-2-hydroxycyclopentyl]adenosine), were examined in a porcine model of myocardial ischaemia-reperfusion injury." | 3.70 | The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig. ( Drew, GM; Hunt, AA; Louttit, JB; Maxwell, MP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadowaki, M | 1 |
| Nagakura, Y | 1 |
| Tokita, K | 1 |
| Hanaoka, K | 1 |
| Tomoi, M | 1 |
| Gu, Q | 1 |
| Ruan, T | 1 |
| Hong, JL | 2 |
| Burki, N | 1 |
| Lee, LY | 2 |
| Auchampach, JA | 1 |
| Jin, X | 1 |
| Moore, J | 1 |
| Wan, TC | 1 |
| Kreckler, LM | 1 |
| Ge, ZD | 1 |
| Narayanan, J | 1 |
| Whalley, E | 1 |
| Kiesman, W | 1 |
| Ticho, B | 1 |
| Smits, G | 1 |
| Gross, GJ | 1 |
| Kalkan, S | 1 |
| Aygoren, O | 1 |
| Akgun, A | 1 |
| Gidener, S | 1 |
| Guven, H | 1 |
| Tuncok, Y | 1 |
| Ma, HC | 1 |
| Wang, YF | 1 |
| Feng, CS | 1 |
| Zhao, H | 1 |
| Dohi, S | 1 |
| Keir, S | 1 |
| Boswell-Smith, V | 1 |
| Spina, D | 1 |
| Page, C | 1 |
| Monopoli, A | 1 |
| Conti, A | 1 |
| Dionisotti, S | 1 |
| Casati, C | 1 |
| Camaioni, E | 1 |
| Cristalli, G | 1 |
| Ongini, E | 1 |
| Dawid-Milner, MS | 1 |
| Silva-Carvalho, L | 1 |
| Goldsmith, GR | 1 |
| Spyer, KM | 2 |
| St Lambert, JH | 1 |
| Dashwood, MR | 1 |
| Kwong, K | 1 |
| Morton, RF | 1 |
| Louttit, JB | 2 |
| Hunt, AA | 1 |
| Maxwell, MP | 1 |
| Drew, GM | 2 |
| Sheldrick, A | 1 |
| Gray, KM | 1 |
12 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Anesthesia
| Article | Year |
|---|---|
Adenosine A1 receptor blockade reverses experimental postoperative ileus in rat colon.
Topics: Anesthesia; Animals; Cecostomy; Colon; Dose-Response Relationship, Drug; Gastrectomy; Gastrointestin | 2003 |
Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Body Weight; Bradycardia; Bronchial Hyperreactivity; Capsaicin; Dose | 2003 |
Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs.
Topics: Adenosine A1 Receptor Antagonists; Anesthesia; Animals; Disease Models, Animal; Dogs; Ischemic Preco | 2004 |
Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats?
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Cardiovascular | 2004 |
Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats.
Topics: 4-Aminopyridine; Adenosine; Adenosine A1 Receptor Antagonists; Analgesia; Analgesics; Anesthesia; An | 2005 |
Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2006 |
Pharmacology of the highly selective A1 adenosine receptor agonist 2-chloro-N6-cyclopentyladenosine.
Topics: Adenosine; Anesthesia; Animals; Behavior, Animal; Cattle; Coronary Circulation; Heart Rate; Hemodyna | 1994 |
A potential role of central A1 adenosine receptors in the responses to hypothalamic stimulation in the anaesthetized cat.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Cats; Chemoreceptor Cells; Electric Stimulation; Eth | 1994 |
Role of brainstem adenosine A1 receptors in the cardiovascular response to hypothalamic defence area stimulation in the anaesthetized rat.
Topics: Anesthesia; Animals; Autoradiography; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; | 1996 |
Role of pulmonary C fibers in adenosine-induced respiratory inhibition in anesthetized rats.
Topics: Adenosine; Anesthesia; Animals; Capsaicin; Chemoreceptor Cells; Heart Ventricles; Injections; Lung; | 1998 |
The time course of cardioprotection induced by GR79236, a selective adenosine A1-receptor agonist, in myocardial ischaemia-reperfusion injury in the pig.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Coronary Disease; Female; Heart Rate; Male; Molecula | 1999 |
The effect of body temperature on myocardial protection conferred by ischaemic preconditioning or the selective adenosine A1 receptor agonist GR79236, in an anaesthetized rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Body Temperature; Heart Rate; Ischemic Preconditioni | 1999 |