1,3-dipropyl-8-cyclopentylxanthine has been researched along with Allodynia in 17 studies
DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Additionally, incarvillateine attenuated mechanical allodynia induced by spared nerve injury or paclitaxel, whereas normal mechanical sensation was not affected." | 3.81 | Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system. ( Gong, ZH; Huang, B; Jia, YX; Su, RB; Wang, ML; Wang, ZT; Yi, SP; Yu, G; Zhang, FY, 2015) |
| "This study investigated the involvement of the adenosinergic system in antiallodynia induced by exercise in an animal model of complex regional pain syndrome type I (CRPS-I)." | 3.79 | High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system. ( Martins, DF; Mazzardo-Martins, L; Piovezan, AP; Santos, AR; Soldi, F; Stramosk, J, 2013) |
| "This study was undertaken in order to investigate the effect of chronic treatment with 5′-chloro-5′-deoxy-(±)-ENBA, a potent and highly selective agonist of human adenosine A(1) receptor, on thermal hyperalgesia and mechanical allodynia in a mouse model of neuropathic pain, the Spared Nerve Injury (SNI) of the sciatic nerve." | 3.78 | 5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions. ( Cappellacci, L; de Novellis, V; Franchetti, P; Gatta, L; Giordano, C; Grifantini, M; Guida, F; Luongo, L; Maione, S; Petrelli, R; Vita, P, 2012) |
| "It is associated with allodynia and hyperalgesia." | 1.48 | Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain. ( Caumo, W; Dos Santos, ARS; Martins, DF; Martins, TC; Medeiros, LF; Nucci-Martins, C; Siteneski, A; Souza, A; Torres, ILS, 2018) |
| "In the primed paw AMP hyperalgesia was dependent on conversion to adenosine, being prevented by ecto-5'nucleotidase inhibitor α,β-methyleneadenosine 5'-diphosphate sodium salt and A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine." | 1.46 | Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor α in the Rat. ( Araldi, D; Ferrari, LF; Levine, JD, 2017) |
| "The adenosinergic system was assessed by systemic (intraperitoneal), central (intrathecal), and peripheral (intraplantar) administration of caffeine." | 1.39 | Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors. ( Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J, 2013) |
| "To evaluate the effect of adenosine on thermal hyperalgesia after spinal cord injury (SCI)." | 1.36 | Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats. ( Horiuchi, H; Morino, T; Ogata, T; Yamamoto, H, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Altenbach, RJ | 1 |
| Carr, TL | 1 |
| Chandran, P | 1 |
| Hsieh, GC | 1 |
| Lewis, LG | 1 |
| Manelli, AM | 1 |
| Milicic, I | 1 |
| Marsh, KC | 1 |
| Miller, TR | 1 |
| Strakhova, MI | 1 |
| Vortherms, TA | 1 |
| Wakefield, BD | 1 |
| Wetter, JM | 1 |
| Witte, DG | 1 |
| Honore, P | 1 |
| Esbenshade, TA | 1 |
| Brioni, JD | 1 |
| Cowart, MD | 1 |
| Xie, AX | 1 |
| Madayag, A | 1 |
| Minton, SK | 1 |
| McCarthy, KD | 1 |
| Malykhina, AP | 1 |
| Souza, A | 1 |
| Martins, DF | 3 |
| Medeiros, LF | 1 |
| Nucci-Martins, C | 1 |
| Martins, TC | 1 |
| Siteneski, A | 1 |
| Caumo, W | 1 |
| Dos Santos, ARS | 1 |
| Torres, ILS | 1 |
| Imlach, WL | 1 |
| Bhola, RF | 1 |
| May, LT | 1 |
| Christopoulos, A | 1 |
| Christie, MJ | 1 |
| Wang, ML | 1 |
| Yu, G | 1 |
| Yi, SP | 1 |
| Zhang, FY | 1 |
| Wang, ZT | 1 |
| Huang, B | 1 |
| Su, RB | 1 |
| Jia, YX | 1 |
| Gong, ZH | 1 |
| Ferrari, LF | 1 |
| Araldi, D | 1 |
| Levine, JD | 1 |
| Horiuchi, H | 1 |
| Ogata, T | 1 |
| Morino, T | 1 |
| Yamamoto, H | 1 |
| Lima, FO | 1 |
| Souza, GR | 1 |
| Verri, WA | 1 |
| Parada, CA | 1 |
| Ferreira, SH | 1 |
| Cunha, FQ | 1 |
| Cunha, TM | 1 |
| Mazzardo-Martins, L | 2 |
| Cidral-Filho, FJ | 1 |
| Stramosk, J | 2 |
| Santos, AR | 2 |
| Luongo, L | 1 |
| Petrelli, R | 1 |
| Gatta, L | 1 |
| Giordano, C | 1 |
| Guida, F | 1 |
| Vita, P | 1 |
| Franchetti, P | 1 |
| Grifantini, M | 1 |
| de Novellis, V | 1 |
| Cappellacci, L | 1 |
| Maione, S | 1 |
| Soldi, F | 1 |
| Piovezan, AP | 1 |
| da Silva Torres, IL | 1 |
| Bonan, CD | 1 |
| Crema, L | 1 |
| De Leon Nunes, M | 1 |
| Battastini, AM | 1 |
| Sarkis, JJ | 1 |
| Dalmaz, C | 1 |
| Ferreira, MB | 1 |
| Wu, WP | 1 |
| Hao, JX | 1 |
| Halldner, L | 1 |
| Lövdahl, C | 1 |
| DeLander, GE | 1 |
| Wiesenfeld-Hallin, Z | 1 |
| Fredholm, BB | 1 |
| Xu, XJ | 1 |
| Vuckovic, S | 1 |
| Tomic, M | 1 |
| Stepanovic-Petrovic, R | 1 |
| Ugresic, N | 2 |
| Prostran, M | 1 |
| Boskovic, B | 2 |
| Tomić, MA | 1 |
| Vucković, SM | 1 |
| Stepanović-Petrović, RM | 1 |
| Prostran, MS | 1 |
| Savegnago, L | 1 |
| Jesse, CR | 1 |
| Nogueira, CW | 1 |
| Yasuda, T | 1 |
| Okamoto, K | 1 |
| Iwamoto, T | 1 |
| Miki, S | 1 |
| Yoshinaga, N | 1 |
| Sato, S | 1 |
| Noguchi, K | 1 |
| Senba, E | 1 |
17 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Allodynia
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; | 2008 |
Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation.
Topics: Animals; Benzilates; Clozapine; Freund's Adjuvant; Genes, Synthetic; GTP-Binding Protein alpha Subun | 2020 |
Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain.
Topics: Adenosine A1 Receptor Antagonists; Animals; Caffeine; Central Nervous System Stimulants; Disease Mod | 2018 |
A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model.
Topics: Adenosine A1 Receptor Agonists; Allosteric Regulation; Animals; Excitatory Postsynaptic Potentials; | 2015 |
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease | 2015 |
Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor α in the Rat.
Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Monophosphate; Animals; Chr | 2017 |
Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2010 |
Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Carrageenan; Cyclic GMP; Cyclic GM | 2010 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; | 2013 |
5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Cardiovascular System; Humans; Hyperalgesia; Mic | 2012 |
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Adenosine | 2013 |
Effect of drugs active at adenosine receptors upon chronic stress-induced hyperalgesia in rats.
Topics: Adenosine; Animals; Chronic Disease; Hyperalgesia; Male; Pain Measurement; Purinergic P1 Receptor Ag | 2003 |
Increased nociceptive response in mice lacking the adenosine A1 receptor.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Analysis of V | 2005 |
Peripheral antinociception by carbamazepine in an inflammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine?
Topics: Analgesics; Animals; Caffeine; Carbamazepine; Concanavalin A; Disease Models, Animal; Dose-Response | 2006 |
Peripheral anti-hyperalgesia by oxcarbazepine: involvement of adenosine A1 receptors.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Caffein | 2006 |
Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Benzene Derivatives; Benzofurans; Caffeine; | 2008 |
A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception.
Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Guinea Pigs; Hyperalgesia; Imm | 2001 |