Page last updated: 2024-10-21

1,3-dipropyl-8-cyclopentylxanthine and Acute Kidney Failure

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Acute Kidney Failure in 12 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (66.67)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suzuki, F1
Shimada, J1
Mizumoto, H1
Karasawa, A1
Kubo, K1
Nonaka, H1
Ishii, A1
Kawakita, T1
Moosavi, SM1
Bayat, G1
Owji, SM1
Panjehshahin, MR2
Park, SW1
Kim, JY1
Ham, A1
Brown, KM1
Kim, M2
D'Agati, VD1
Lee, HT3
Xu, H1
Nasr, SH1
Schnermann, J1
Emala, CW1
Jan, M1
Bae, SC1
Joo, JD1
Goubaeva, FR1
Yang, J1
Knight, RJ2
Bowmer, CJ5
Yates, MS5
Gould, J2
Morton, MJ1
Sivaprasadarao, A1
Erley, CM2
Heyne, N2
Burgert, K1
Langanke, J1
Risler, T2
Osswald, H2
Rossmeier, S1
Vogel, T1
Chahil, RS1
Collis, MG2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02276170]9 participants (Actual)Observational2014-10-31Terminated (stopped due to insufficient rate of accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

12 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Acute Kidney Failure

ArticleYear
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure.
    Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16

    Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligan

1992
Early renal post-ischaemic tissue damage and dysfunction with contribution of A1-adenosine receptor activation in rat.
    Nephrology (Carlton, Vic.), 2009, Volume: 14, Issue:2

    Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Ischemia; Kidney; Male; Microscopy,

2009
A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.
    American journal of physiology. Renal physiology, 2012, Volume: 303, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cells, Cultured; Humans; Kidney; Kidney Tubules, Proximal;

2012
A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion.
    American journal of physiology. Renal physiology, 2004, Volume: 286, Issue:2

    Topics: Acute Kidney Injury; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Biomarkers; G

2004
A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6

    Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Cells, Cultured; Contras

2006
Effect of the selective A1 adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine on acute renal dysfunction induced by Escherichia coli endotoxin in rats.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Animals; Chlorides; Endotoxins; Escherichia coli; Inulin; Kidney Function Tests

1993
Renal haemodynamic responses to adenosine in acute renal failure.
    Nephron, 1995, Volume: 71, Issue:2

    Topics: Acute Kidney Injury; Adenosine; Animals; Disease Models, Animal; Glycerol; Hemodynamics; Male; Mercu

1995
Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.
    British journal of pharmacology, 1997, Volume: 120, Issue:5

    Topics: Acute Kidney Injury; Animals; Cell Membrane; Gene Expression; Kidney; Male; Protein Binding; Rats; R

1997
Prevention of radiocontrast-induced nephropathy by adenosine antagonists in rats with chronic nitric oxide deficiency.
    Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:7

    Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Disease Models, Animal; Enz

1997
Adenosine and extracellular volume in radiocontrast media-induced nephropathy.
    Kidney international. Supplement, 1998, Volume: 67

    Topics: Acute Kidney Injury; Adenosine; Animals; Blood Pressure; Contrast Media; Enzyme Inhibitors; Extracel

1998
The effect of 8-cyclopentyl-1,3-dipropylxanthine on the development of cyclosporin-induced acute renal failure.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:7

    Topics: Acute Kidney Injury; Animals; Creatinine; Cyclosporins; Injections, Intraperitoneal; Inulin; Male; p

1991
Amelioration of cisplatin-induced acute renal failure with 8-cyclopentyl-1,3-dipropylxanthine.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Acute Kidney Injury; Adenosine; Animals; Cisplatin; Creatinine; Dose-Response Relationship, Drug; El

1991