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1,3-dipropyl-8-cyclopentylxanthine and Acute Brain Injuries

1,3-dipropyl-8-cyclopentylxanthine has been researched along with Acute Brain Injuries in 3 studies

DPCPX : An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.

Research Excerpts

ExcerptRelevanceReference
"In addition, demyelination and axonal damage in brainstem were exacerbated, levels of Th1 cytokines increased, and Th2 cytokines decreased."1.38Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis. ( Augusto, E; Chen, JF; He, JC; Huang, QY; Li, F; Li, ZZ; Wang, XT; Wang, ZW; Yao, SQ; Zheng, RY, 2012)
"Adenosine is an endogenous neuroprotectant via anti-excitotoxic effects at A(1) receptors, and blood flow promoting and anti-inflammatory effects at A(2a) receptors."1.31Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology. ( Clark, RS; Dixon, CE; Griffith, RP; Jackson, EK; Jenkins, LW; Kochanek, PM; Melick, JA; Peters, GW; Vagni, VA; Varma, MR, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ortiz, F1
GutiƩrrez, R1
Yao, SQ1
Li, ZZ1
Huang, QY1
Li, F1
Wang, ZW1
Augusto, E1
He, JC1
Wang, XT1
Chen, JF1
Zheng, RY1
Varma, MR1
Dixon, CE1
Jackson, EK1
Peters, GW1
Melick, JA1
Griffith, RP1
Vagni, VA1
Clark, RS1
Jenkins, LW1
Kochanek, PM1

Other Studies

3 other studies available for 1,3-dipropyl-8-cyclopentylxanthine and Acute Brain Injuries

ArticleYear
Entorhinal cortex lesions result in adenosine-sensitive high frequency oscillations in the hippocampus.
    Experimental neurology, 2015, Volume: 271

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biological Clocks; Brain Injuries; Brain Wave

2015
Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis.
    Journal of neurochemistry, 2012, Volume: 123, Issue:1

    Topics: Adenosine A1 Receptor Antagonists; Animals; Astrocytes; Axons; Brain Injuries; Cell Proliferation; C

2012
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
    Brain research, 2002, Oct-04, Volume: 951, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; M

2002