1,3-dipropyl-8-(4-sulfophenyl)xanthine has been researched along with Blood Pressure, High in 22 studies
1,3-dipropyl-8-(4-sulfophenyl)xanthine: adenosine receptor antagonist
| Excerpt | Relevance | Reference |
|---|---|---|
| "Captopril was given (30 or 100 mg kg(-l) day(-l); p." | 1.31 | Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors. ( Albino-Teixeira, A; Morato, M; Sousa, T, 2002) |
| "The study was undertaken to test the endothelium-mediated vascular responses in rats rendered hypertensive by chronic administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX)." | 1.30 | Endothelium-dependent vascular responses in 1,3-dipropyl-8-sulphophenylxanthine (DPSPX) hypertensive rats. ( Albino-Teixeira, A; Paiva, MQ; Santos, MJ, 1997) |
| " Long-term administration of the adenosine receptor antagonist, 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), causes arterial hypertension and cardiovascular hypertrophic and hyperplastic changes (Matias, Albino-Teixeira, Polónia & Azevedo, 1991)." | 1.30 | Prevention by a somatostatin analogue of the hypertensive and cardiovascular structural changes induced by blockade of adenosine receptors. ( Alçada, MN; Azevedo, I; Calhau, C; Martel, F, 1997) |
| "Adenosine is an ubiquitously occurring endogenous nucleoside that via cell surface receptors exerts multiple antihypertensive actions, and mediates a number of biological responses that may reduce cardiovascular disease risk." | 1.30 | Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats. ( Jackson, EK; Kusaka, H; Li, P; Tofovic, SP, 1998) |
| " The study was undertaken to compare the beta-adrenoceptor-mediated facilitation of noradrenaline release in the tail artery of vehicle-treated rats and of rats rendered hypertensive by chronic administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX)." | 1.29 | Hypertension and enhanced beta-adrenoceptor-mediated facilitation of noradrenaline release produced by chronic blockade of adenosine receptors. ( Albino-Teixeira, A; Guimarães, S; Paiva, MQ, 1995) |
| "Adenosine has been shown recently to be the main factor responsible for the trophic effects of sympathetic innervation." | 1.28 | Long-term administration of 1,3-dipropyl-8-sulfophenylxanthine causes arterial hypertension. ( Albino-Teixeira, A; Azevedo, I; Matias, A; Polónia, J, 1991) |
| " Antagonism of adenosine receptors with 1,3-dipropyl-8-p-sulfophenylxanthine shifted the dose-response curve to exogenous adenosine sixfold to the right yet did not influence vascular responses to PNS or NE in either SHR or WKY." | 1.27 | Role of adenosine in noradrenergic neurotransmission in spontaneously hypertensive rats. ( Jackson, EK, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sousa, T | 9 |
| Pinho, D | 4 |
| Morato, M | 9 |
| Marques-Lopes, J | 1 |
| Fernandes, E | 2 |
| Afonso, J | 1 |
| Oliveira, S | 1 |
| Carvalho, F | 2 |
| Albino-Teixeira, A | 15 |
| Guimarães, S | 7 |
| Moura, D | 4 |
| Tavares, I | 2 |
| Jackson, EK | 3 |
| Mi, Z | 1 |
| Dubey, RK | 1 |
| Rubino, A | 2 |
| Burnstock, G | 2 |
| Paiva, MQ | 3 |
| Vaz-da-Silva, MJ | 1 |
| Relevic, V | 1 |
| Santos, MJ | 1 |
| Calhau, C | 1 |
| Martel, F | 1 |
| Alçada, MN | 1 |
| Azevedo, I | 3 |
| Tofovic, SP | 1 |
| Kusaka, H | 1 |
| Li, P | 1 |
| Matias, A | 2 |
| Polónia, J | 2 |
| Persson, MG | 1 |
| Ohlén, A | 1 |
| Lindbom, L | 1 |
| Hedqvist, P | 1 |
| Gustafsson, LE | 1 |
2 reviews available for 1,3-dipropyl-8-(4-sulfophenyl)xanthine and Blood Pressure, High
| Article | Year |
|---|---|
Hypertension due to blockade of adenosine receptors.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart; Hypertension; Norepinephrine; Purinergic P1 | 2003 |
Hypertension due to chronic blockade of P1-purinoceptors.
Topics: Animals; Hypertension; Mesenteric Arteries; Myocardial Contraction; Purinergic P1 Receptor Antagonis | 1996 |
20 other studies available for 1,3-dipropyl-8-(4-sulfophenyl)xanthine and Blood Pressure, High
| Article | Year |
|---|---|
Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.
Topics: Acetophenones; Animals; Blood Vessels; Catalase; Hydrogen Peroxide; Hypertension; Lipid Peroxidation | 2008 |
The role of angiotensin II in hypertension due to adenosine receptors blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; In Vitro Te | 2002 |
Losartan and atenolol on hypertension induced by adenosine receptor blockade.
Topics: Administration, Oral; Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type 2 Receptor Blocker | 2003 |
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Free Radical Scavengers; Hypertension; Oxidants; O | 2004 |
Pre- and postjunctional effects of angiotensin II in hypertension due to adenosine receptor blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Hyp | 2006 |
Inhibition of nociceptive responses of spinal cord neurones during hypertension involves the spinal GABAergic system and a pain modulatory center located at the caudal ventrolateral medulla.
Topics: Animals; Blood Pressure; gamma-Aminobutyric Acid; Gene Expression; Genes, fos; Hindlimb; Hypertensio | 2006 |
Lesion of the caudal ventrolateral medulla prevents the induction of hypertension by adenosine receptor blockade in rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Purinergic P1 | 2006 |
The extracellular cAMP-adenosine pathway significantly contributes to the in vivo production of adenosine.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Cyclic AMP; Hypertension; Male; Rats; Rats, Inbred | 2007 |
Changes in sympathetic neurotransmission and adrenergic control of cardiac contractility during 1,3-dipropyl-8-sulfophenylxanthine-induced hypertension.
Topics: Adenosine; Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Depression, Chemical; Dis | 1995 |
Hypertension and enhanced beta-adrenoceptor-mediated facilitation of noradrenaline release produced by chronic blockade of adenosine receptors.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Isoproteren | 1995 |
Long-term administration of 1,3-dipropyl-8-sulphophenylxanthine (DPSPX) alters alpha 2-adrenoceptor-mediated effects at the pre- but not at the postjunctional level.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Arteries; Brimonidine Tartrate; Hypertension; Male; Ne | 1994 |
Augmented sensory-motor vasodilatation of the rat mesenteric arterial bed after chronic infusion of the P1-purinoceptor antagonist, DPSPX.
Topics: Adenosine; Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Hypertension; In Vitro Te | 1996 |
Endothelium-dependent vascular responses in 1,3-dipropyl-8-sulphophenylxanthine (DPSPX) hypertensive rats.
Topics: Animals; Blood Pressure; Carbachol; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Meth | 1997 |
Prevention by a somatostatin analogue of the hypertensive and cardiovascular structural changes induced by blockade of adenosine receptors.
Topics: Animals; Blood Pressure; Hormones; Hypertension; Muscle, Smooth, Vascular; Octreotide; Purinergic P1 | 1997 |
Effects of adenosine deaminase inhibition on blood pressure in old spontaneously hypertensive rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Aging; Animals; Blood Pressure; Enzyme Inhibitor | 1998 |
Angiotensin converting enzyme inhibition prevents trophic and hypertensive effects of an antagonist of adenosine receptors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Body Weight; Captopril; | 2002 |
Blockade of adenosine receptors causes hypertension and cardiovascular structural changes in the rat.
Topics: Adenosine; Animals; Arteries; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Mesent | 1991 |
Role of adenosine in functional hyperemia in skeletal muscle as indicated by pharmacological tools.
Topics: Adenosine; Administration, Topical; Animals; Arterioles; Dipyridamole; Dose-Response Relationship, D | 1991 |
Long-term administration of 1,3-dipropyl-8-sulfophenylxanthine causes arterial hypertension.
Topics: Adenosine; Animals; Arteries; Blood Pressure; Blood Vessels; Hypertension; In Vitro Techniques; Musc | 1991 |
Role of adenosine in noradrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Hyperten | 1987 |