1-3-dimethylthiourea has been researched along with Autoimmune-Diseases* in 1 studies
1 other study(ies) available for 1-3-dimethylthiourea and Autoimmune-Diseases
Article | Year |
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Long-term treatment with dimethylthiourea inhibits the development of autoimmune disease in NZB x NZWF1 mice.
Long-term treatment with dimethylthiourea (DMTU), a scavenger of hydroxyl radical (.OH) and hypochlorous acid (HOCl), suppressed the age-related development of autoimmune disease in NZB x NZWF1 mice. Treatment reduced autoantibody production, retarded increase in blood urea nitrogen, and prolonged life. The results suggest that .OH and HOCl may, at least in part, enhance the development of autoimmune diseases in NZB x NZWF1 mice. Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; Blood Urea Nitrogen; Body Weight; Female; Free Radical Scavengers; Mice; Mice, Inbred NZB; Survival Rate; Thiourea | 1995 |