Page last updated: 2024-08-18

1,3-butadiene and Lung Neoplasms

1,3-butadiene has been researched along with Lung Neoplasms in 25 studies

*Lung Neoplasms: Tumors or cancer of the LUNG. [MeSH]

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (8.00)	18.7374
1990's	9 (36.00)	18.2507
2000's	7 (28.00)	29.6817
2010's	4 (16.00)	24.3611
2020's	3 (12.00)	2.80

Authors

Authors	Studies
Ameredes, BT; Boysen, G; Caperton, CO; Go, YM; Hallberg, LM; Jones, DP; Liu, K; Nellis, M; Tran, V	1
Brill, I; Delzell, E; Leader, M; Sathiakumar, N; Tipre, M	1
Boldry, EJ; Carmella, SG; Hatsukami, DK; Hecht, SS; Tessier, K; Tretyakova, NY; Wang, R; Yuan, JM	1
Arora, T; Bolaji, B; Brill, I; Chen, L; Delzell, E; Leader, M; Sathiakumar, N; Tipre, M	1
Kotapati, S; Le Marchand, L; Murphy, SE; Park, SL; Tiirikainen, M; Tretyakova, N; Wilkens, LR	1
Boldry, EJ; Esades, A; Kotapati, S; Le Marchand, L; Park, SL; Patel, YM; Stram, DO; Tiirikainen, M; Tretyakova, N	1
Brill, I; Delzell, E; Sathiakumar, N	1
Claffey, DJ; Henderson, RF; McDonald, JD; Meng, Q; Powley, MW; Scott, BR; Seilkop, SK; Swenberg, JA; Upton, PB; Walker, DM; Walker, VE	1
Ducatman, A; Hendryx, M; Luo, J	1
Broderick, B; Gill, L; Johnston, P; McNabola, A	1
Devereux, TR; Hong, HH; Kim, Y; Melnick, RL; Sills, RC; Ton, TV	1
Austin, DF; Luo, W; Pankow, JF; Toccalino, PL; Watanabe, KH	1
Bailer, AJ; Smith, RJ	1
Cochran, C; Dietrich, W; Lander, ES; Söderkvist, P; Wiseman, RW	1
Dybing, E; Kroese, D; Roelfzema, H; Sanner, T; Tennant, RW	1
Blair, A; Kazerouni, N	1
Boorman, GA; Devereux, TR; Hong, HL; Melnick, RL; Sills, RC	1
Chou, BJ; Grumbein, SL; Melnick, RL; Miller, RA; Portier, CJ; Roycroft, JH; Sills, RC	1
Blair, L; Henderson, RF; Long, L; Meng, Q; Swenberg, JA; Upton, PB; Walker, DM; Walker, VE	1
Anderson, D	1
Anderson, M; Goodrow, T; Maronpot, R; Reynolds, S	1
Chou, BJ; Huff, J; Melnick, RL; Miller, RA	1
Boorman, GA; Miller, RA	1
Boorman, GA; Melnick, RL; Miller, RA	1
Haseman, JK; Huff, JE; Melnick, RL; Miller, RA; Powers, M; Solleveld, HA	1

Reviews

1 review(s) available for 1,3-butadiene and Lung Neoplasms

Article	Year
Reactive chemicals and cancer. Cancer causes & control : CCC, 1997, Volume: 8, Issue:3 Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Studies; England; Environmental Exposure; Ethylene Oxide; Follow-Up Studies; Formaldehyde; Hemangiosarcoma; Humans; Laryngeal Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Methyl Ethers; Mustard Gas; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Nose Neoplasms; Occupational Diseases; Occupational Exposure; Organic Chemicals; Risk Factors; Sulfuric Acids; Sweden; Vinyl Chloride	1997

Article

Year

Reactive chemicals and cancer.

Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Studies; England; Environmental Exposure; Ethylene Oxide; Follow-Up Studies; Formaldehyde; Hemangiosarcoma; Humans; Laryngeal Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Methyl Ethers; Mustard Gas; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Nose Neoplasms; Occupational Diseases; Occupational Exposure; Organic Chemicals; Risk Factors; Sulfuric Acids; Sweden; Vinyl Chloride

1997

Trials

1 trial(s) available for 1,3-butadiene and Lung Neoplasms

Article	Year
Effects of 2-Phenethyl Isothiocyanate on Metabolism of 1,3-Butadiene in Smokers. Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:1 Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Butadienes; Carcinogens; Cigarette Smoking; Feeding Behavior; Female; Genotyping Techniques; Glutathione Transferase; Humans; Isothiocyanates; Lung Neoplasms; Male; Middle Aged; Smokers	2020

Article

Year

Effects of 2-Phenethyl Isothiocyanate on Metabolism of 1,3-Butadiene in Smokers.

Cancer prevention research (Philadelphia, Pa.), 2020, Volume: 13, Issue:1

Topics: Administration, Oral; Adult; Anticarcinogenic Agents; Butadienes; Carcinogens; Cigarette Smoking; Feeding Behavior; Female; Genotyping Techniques; Glutathione Transferase; Humans; Isothiocyanates; Lung Neoplasms; Male; Middle Aged; Smokers

2020

Other Studies

23 other study(ies) available for 1,3-butadiene and Lung Neoplasms

Article	Year
Lung metabolome of 1,3-butadiene exposed Collaborative Cross mice reflects metabolic phenotype of human lung cancer. Toxicology, 2021, Volume: 463 Topics: Animals; Butadienes; Carcinogens; Collaborative Cross Mice; Dose-Response Relationship, Drug; Female; Humans; Lipid Metabolism; Lung; Lung Neoplasms; Mass Spectrometry; Metabolome; Metabolomics; Mice; Phenotype	2021
Mortality Among Men and Women in the North American Synthetic Rubber Industry, 1943 to 2009. Journal of occupational and environmental medicine, 2019, Volume: 61, Issue:11 Topics: Aged; Aged, 80 and over; Butadienes; Canada; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Manufacturing Industry; Middle Aged; Mortality; Neoplasms; Occupational Exposure; Proportional Hazards Models; Rubber; Styrene; Time Factors; United States; Urinary Bladder Neoplasms	2019
1,3-Butadiene, styrene and selected outcomes among synthetic rubber polymer workers: Updated exposure-response analyses. Chemico-biological interactions, 2021, Sep-25, Volume: 347 Topics: Aged; Butadienes; Canada; Carcinogens; Chemical Industry; Cohort Studies; Elastomers; Female; Humans; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Proportional Hazards Models; Pulmonary Disease, Chronic Obstructive; Sex Factors; Styrene; United States; Urinary Bladder Neoplasms	2021
1,3-Butadiene exposure and metabolism among Japanese American, Native Hawaiian, and White smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014, Volume: 23, Issue:11 Topics: Acetylcysteine; Asian; Butadienes; Female; Genotype; Glutathione Transferase; Hawaii; Humans; Japan; Lung Neoplasms; Male; Native Hawaiian or Other Pacific Islander; Sex Factors; Smoking; White People	2014
Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2017, Volume: 26, Issue:7 Topics: Acetylcysteine; Aged; Asian; Biomarkers; Black or African American; Butadienes; Carcinogens; Female; Gene Deletion; Gene Dosage; Genome-Wide Association Study; Glutathione; Glutathione Transferase; Humans; Lung Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Smokers; Smoking; White People	2017
1,3-butadiene, styrene and lung cancer among synthetic rubber industry workers. Journal of occupational and environmental medicine, 2009, Volume: 51, Issue:11 Topics: Aged; Butadienes; Carcinogens; Databases as Topic; Female; Humans; Lung Neoplasms; Male; Middle Aged; Occupational Exposure; Proportional Hazards Models; Rubber; Styrenes	2009
Genotoxicity of 1,3-butadiene and its epoxy intermediates. Research report (Health Effects Institute), 2009, Issue:144 Topics: Alkylating Agents; Animals; Butadienes; Carcinogenicity Tests; DNA Mutational Analysis; Environmental Exposure; Epoxy Compounds; Female; Humans; Lung Neoplasms; Male; Mice; Mutagenesis; Mutagenicity Tests; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Risk Factors; United States	2009
Association between six environmental chemicals and lung cancer incidence in the United States. Journal of environmental and public health, 2011, Volume: 2011 Topics: Analysis of Variance; Arsenic; Butadienes; Carcinogens, Environmental; Environmental Exposure; Female; Formaldehyde; Hazardous Substances; Humans; Incidence; Linear Models; Lung Neoplasms; Male; Metals, Heavy; SEER Program; United States	2011
Effects of the smoking ban on benzene and 1,3-butadiene levels in pubs in Dublin. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2006, Volume: 41, Issue:5 Topics: Air Pollutants, Occupational; Benzene; Butadienes; Cities; Humans; Ireland; Lung Neoplasms; Occupational Exposure; Respiratory Tract Infections; Restaurants; Risk Assessment; Time Factors; Tobacco Smoke Pollution	2006
Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene. Chemico-biological interactions, 2007, Mar-20, Volume: 166, Issue:1-3 Topics: Alleles; Animals; Brain Neoplasms; Butadienes; Carcinogens; Chloroprene; Chromosomes, Mammalian; DNA Adducts; Female; Genes, Neoplasm; Genes, ras; Humans; Inhalation Exposure; Loss of Heterozygosity; Lung Neoplasms; Male; Mice; Mutagenesis	2007
Calculated cancer risks for conventional and "potentially reduced exposure product" cigarettes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:3 Topics: Acetaldehyde; Acrylonitrile; Biomarkers; Butadienes; Carcinogens; Humans; Lung; Lung Neoplasms; Risk Assessment; Smoking; Tars	2007
Model-based time extrapolation for quantal response studies. Biometrics, 1994, Volume: 50, Issue:1 Topics: Animals; Biometry; Butadienes; Carcinogenicity Tests; Female; Lung Neoplasms; Models, Statistical; Proportional Hazards Models; Stochastic Processes; Time Factors	1994
Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes. Proceedings of the National Academy of Sciences of the United States of America, 1994, Apr-26, Volume: 91, Issue:9 Topics: Adenocarcinoma; Alleles; Animals; Base Sequence; Butadienes; Chromosome Mapping; DNA Primers; DNA, Neoplasm; Female; Genes, Retinoblastoma; Genes, Tumor Suppressor; Heterozygote; Humans; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Polymorphism, Genetic; Sequence Deletion	1994
T25: a simplified carcinogenic potency index: description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicity. Pharmacology & toxicology, 1997, Volume: 80, Issue:6 Topics: Abdominal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Butadienes; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Transitional Cell; Chloroform; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mesothelioma; Mice; Mutagenesis; Neoplasms, Experimental; Rats; Rats, Inbred F344; Species Specificity; Toluidines; Urinary Bladder Neoplasms	1997
High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene. Carcinogenesis, 1999, Volume: 20, Issue:4 Topics: Adenoma; Administration, Inhalation; Animals; Butadienes; Carcinogens; Carcinoma; Chloroprene; Codon; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Genes, ras; Harderian Gland; Hemiterpenes; Lung Neoplasms; Male; Mice; Organ Specificity; Pentanes; Point Mutation; Polymorphism, Single-Stranded Conformational; Sebaceous Gland Neoplasms; Structure-Activity Relationship	1999
Multiple organ carcinogenicity of inhaled chloroprene (2-chloro-1,3-butadiene) in F344/N rats and B6C3F1 mice and comparison of dose-response with 1,3-butadiene in mice. Carcinogenesis, 1999, Volume: 20, Issue:5 Topics: Administration, Inhalation; Animals; Butadienes; Carcinogens; Chloroprene; Dose-Response Relationship, Drug; Female; Kidney Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Animal; Mice; Neoplasms, Experimental; Rats; Rats, Inbred F344; Species Specificity	1999
Mutagenicity at the Hprt locus in T cells of female mice following inhalation exposures to low levels of 1,3-butadiene. Chemico-biological interactions, 2001, Jun-01, Volume: 135-136 Topics: Administration, Inhalation; Animals; Butadienes; Carcinogenicity Tests; Carcinogens; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Female; Hypoxanthine Phosphoribosyltransferase; Lung Neoplasms; Mice; Mutagenicity Tests; Mutagens; T-Lymphocytes	2001
Expression of ras (p21) protein in plasma from exposed workers and from patients with lung disease. International journal of hygiene and environmental health, 2001, Volume: 204, Issue:1 Topics: Adult; Aged; Antibodies, Monoclonal; Biomarkers; Blotting, Western; Butadienes; Carcinogens; Case-Control Studies; Female; Gene Expression Regulation; Humans; Luminescent Measurements; Lung Neoplasms; Male; Middle Aged; Occupational Exposure; Proto-Oncogene Mas; Pulmonary Disease, Chronic Obstructive; ras Proteins; Smoking; Styrene	2001
Activation of K-ras by codon 13 mutations in C57BL/6 X C3H F1 mouse tumors induced by exposure to 1,3-butadiene. Cancer research, 1990, Aug-01, Volume: 50, Issue:15 Topics: Animals; Base Sequence; Blotting, Southern; Butadienes; Carcinogens; Cells, Cultured; Codon; DNA, Neoplasm; Gene Expression Regulation; Genes, ras; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; RNA, Messenger; Transfection	1990
Carcinogenicity of 1,3-butadiene in C57BL/6 x C3H F1 mice at low exposure concentrations. Cancer research, 1990, Oct-15, Volume: 50, Issue:20 Topics: Animals; Butadienes; Dose-Response Relationship, Drug; Female; Heart Neoplasms; Hemangiosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Stomach Neoplasms	1990
Morphology of neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice. Environmental health perspectives, 1990, Volume: 86 Topics: Animals; Butadienes; Carcinogens; Female; Heart Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Ovarian Neoplasms; Stomach Neoplasms	1990
Neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice. Experimental pathology, 1989, Volume: 37, Issue:1-4 Topics: Adenocarcinoma; Adenoma; Animals; Butadienes; Carcinoma; Female; Granulosa Cell Tumor; Heart Neoplasms; Hemangiosarcoma; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mice; Mutagens; Neoplasms, Experimental; Ovarian Neoplasms; Stomach Neoplasms	1989
Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure. Science (New York, N.Y.), 1985, Feb-01, Volume: 227, Issue:4686 Topics: Air Pollutants, Occupational; Animals; Body Weight; Brain Neoplasms; Butadienes; Female; Heart Neoplasms; Inflammation; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mammary Glands, Animal; Mice; Mice, Inbred Strains; Neoplasms; Nose Diseases; Ovarian Neoplasms; Stomach Neoplasms	1985