Page last updated: 2024-08-18

1,3-butadiene and Experimental Neoplasms

1,3-butadiene has been researched along with Experimental Neoplasms in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.25)18.7374
1990's23 (71.88)18.2507
2000's7 (21.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldstein, BD; Warren, J1
Jacobson-Kram, D; Rosenthal, SL1
Kohn, MC; Melnick, RL1
Andjelkovich, D; Bond, JA; Recio, L1
Anderson, MW; Goodrow, TL; Maronpot, RR; Nichols, WW; Storer, RD1
Huff, JE; Melnick, RL1
Chou, BJ; Melnick, RL; Miller, RA; Ragan, HA; Roycroft, JH; Sills, RC1
Dybing, E; Kroese, D; Roelfzema, H; Sanner, T; Tennant, RW1
Haugen-Strano, A; Schippert, A; Söderkvist, P; Wiseman, RW; Zhuang, SM1
Blair, A; Kazerouni, N1
Chou, BJ; Grumbein, SL; Melnick, RL; Miller, RA; Portier, CJ; Roycroft, JH; Sills, RC1
Barr, EB; Belinsky, SA; Benson, JM; Hahn, FF; Henderson, RF; Ménache, MG1
Blair, IA; Chaudhary, AK; Kambouris, S; Oe, T1
Recio, L; Saranko, CJ; Steen, AM1
Meng, Q; Walker, VE1
Christova-Gueorguieva, NI; Hayes, R; Ranasinghe, A; Scheller, N; Swenberg, JA; Upton, PB; Wu, KY; Yen, TY1
Jackson, MA; Rice, JM; Stack, HF; Waters, MD1
Melnick, RL; Sills, RC1
Bailer, AJ; Dankovic, DA; Smith, RJ; Stayner, LT1
Rall, DP1
Huff, J; Melnick, RL1
Chichłowska-Sliwińska, M; Sasiadek, M1
Brett, SM; Rodricks, JV; Turnbull, D1
Chou, BJ; Huff, J; Melnick, RL; Miller, RA1
Acquavella, JF1
Grossman, EA; Martonik, J1
Glaister, JR; Owen, PE1
Chou, BJ; Huff, JE; Melnick, RL; Miller, RA; Roycroft, JH1
Boorman, GA; Miller, RA1
Boorman, GA; Melnick, RL; Miller, RA1
de Meester, C1

Reviews

12 review(s) available for 1,3-butadiene and Experimental Neoplasms

ArticleYear
Molecular and genetic toxicology of 1,3-butadiene.
    Mutation research, 1995, Volume: 339, Issue:2

    Topics: Air Pollutants, Occupational; Alkylating Agents; Animals; Butadienes; Cricetinae; Cross-Linking Reagents; DNA Damage; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mice; Mice, Transgenic; Micronucleus Tests; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Occupational Exposure; Oncogenes; Organ Specificity; Pilot Projects; Rats; Rats, Sprague-Dawley; Sister Chromatid Exchange; Species Specificity

1995
Mechanistic data indicate that 1,3-butadiene is a human carcinogen.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Butadienes; Carcinogens; Humans; Mutagens; Neoplasms; Neoplasms, Experimental

1995
Epidemiological and mechanistic data suggest that 1,3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Butadienes; Carcinogens; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Mutagens; Neoplasms; Neoplasms, Experimental; Occupational Exposure; Risk Factors

1995
Inhalation toxicity and carcinogenicity of isoprene in rats and mice: comparisons with 1,3-butadiene.
    Toxicology, 1996, Oct-28, Volume: 113, Issue:1-3

    Topics: Administration, Inhalation; Animals; Butadienes; Carcinogens; Chromosome Aberrations; Hemiterpenes; Male; Mice; Mutagens; Neoplasms, Experimental; Pentanes; Rats

1996
Reactive chemicals and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Studies; England; Environmental Exposure; Ethylene Oxide; Follow-Up Studies; Formaldehyde; Hemangiosarcoma; Humans; Laryngeal Neoplasms; Leukemia; Liver Neoplasms; Lung Neoplasms; Methyl Ethers; Mustard Gas; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Nose Neoplasms; Occupational Diseases; Occupational Exposure; Organic Chemicals; Risk Factors; Sulfuric Acids; Sweden; Vinyl Chloride

1997
1,3-Butadiene.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1999, Volume: 71 Pt 1

    Topics: Animals; Butadienes; Carcinogenicity Tests; Carcinogens; Disease Models, Animal; Environmental Exposure; Environmental Monitoring; Epidemiologic Studies; Epidemiological Monitoring; Global Health; Humans; Maximum Allowable Concentration; Mice; Neoplasms; Neoplasms, Experimental; Rats

1999
A review of the genetic and related effects of 1,3-butadiene in rodents and humans.
    Mutation research, 2000, Volume: 463, Issue:3

    Topics: Air Pollutants, Occupational; Alkylating Agents; Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Biotransformation; Butadienes; Carcinogens; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA; DNA Adducts; DNA Damage; Epoxy Compounds; Female; Glycols; Hemoglobins; Humans; Inactivation, Metabolic; Male; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Occupational Exposure; Organ Specificity; Oxidation-Reduction; Proteins; Rats; Rats, Sprague-Dawley; Single-Blind Method; Sister Chromatid Exchange; Species Specificity

2000
Comparative carcinogenicity of 1,3-butadiene, isoprene, and chloroprene in rats and mice.
    Chemico-biological interactions, 2001, Jun-01, Volume: 135-136

    Topics: Administration, Inhalation; Air Pollutants, Occupational; Animals; Butadienes; Carcinogens; Chloroprene; Female; Hemiterpenes; Humans; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Occupational Exposure; Pentanes; Rats; Risk Factors; Rubber

2001
1,3-Butadiene: toxicity and carcinogenicity in laboratory animals and in humans.
    Reviews of environmental contamination and toxicology, 1992, Volume: 124

    Topics: Administration, Inhalation; Animals; Biotransformation; Butadienes; Carcinogens; Humans; Mutagens; Neoplasms, Experimental

1992
[Genotoxic properties of 1,3-butadiene and its derivatives].
    Medycyna pracy, 1991, Volume: 42, Issue:3

    Topics: Animals; Butadienes; Chromosome Aberrations; DNA Damage; Epoxy Compounds; In Vitro Techniques; Mice; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Rats; Sister Chromatid Exchange

1991
Assessment of the potential risk to workers from exposure to 1,3-butadiene.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Animals; Butadienes; Carcinogens; Cohort Studies; Environmental Exposure; Female; Humans; Male; Mice; Mutagens; Neoplasms; Neoplasms, Experimental; Occupational Diseases; Rats; Risk Factors

1990
Genotoxic properties of 1,3-butadiene.
    Mutation research, 1988, Volume: 195, Issue:3

    Topics: Animals; Biotransformation; Butadienes; DNA Damage; Female; Guinea Pigs; Lung; Male; Mice; Microsomes, Liver; Mutagenicity Tests; Neoplasms; Neoplasms, Experimental; Occupational Diseases; Rabbits; Rats; Reproduction; Salmonella typhimurium; Sister Chromatid Exchange

1988

Other Studies

20 other study(ies) available for 1,3-butadiene and Experimental Neoplasms

ArticleYear
HEI's mobile air toxics project.
    Environmental health perspectives, 1993, Volume: 101, Issue:3

    Topics: Animals; Benzene; Butadienes; Formaldehyde; Humans; Mutagens; Neoplasms; Neoplasms, Experimental; Research; Risk Factors; Vehicle Emissions

1993
Activation of H-ras is prevalent in 1,3-butadiene-induced and spontaneously occurring murine Harderian gland tumors.
    Carcinogenesis, 1994, Volume: 15, Issue:11

    Topics: Animals; Base Sequence; Butadienes; Gene Expression Regulation; Genes, ras; Harderian Gland; Mice; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Rodent Diseases

1994
1,3-Butadiene induces cancer in experimental animals at all concentrations from 6.25 to 8000 parts per million.
    IARC scientific publications, 1993, Issue:127

    Topics: Animals; Butadienes; Carcinogens; Female; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley

1993
T25: a simplified carcinogenic potency index: description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicity.
    Pharmacology & toxicology, 1997, Volume: 80, Issue:6

    Topics: Abdominal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Butadienes; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Transitional Cell; Chloroform; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mesothelioma; Mice; Mutagenesis; Neoplasms, Experimental; Rats; Rats, Inbred F344; Species Specificity; Toluidines; Urinary Bladder Neoplasms

1997
Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas.
    Oncogene, 1998, Feb-12, Volume: 16, Issue:6

    Topics: Animals; Butadienes; Carcinogens; Carrier Proteins; Cell Cycle Proteins; CpG Islands; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA, Neoplasm; Homozygote; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Point Mutation; Polymorphism, Single-Stranded Conformational; Promoter Regions, Genetic; Sequence Analysis, DNA; Tumor Suppressor Proteins; Zalcitabine

1998
Multiple organ carcinogenicity of inhaled chloroprene (2-chloro-1,3-butadiene) in F344/N rats and B6C3F1 mice and comparison of dose-response with 1,3-butadiene in mice.
    Carcinogenesis, 1999, Volume: 20, Issue:5

    Topics: Administration, Inhalation; Animals; Butadienes; Carcinogens; Chloroprene; Dose-Response Relationship, Drug; Female; Kidney Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Animal; Mice; Neoplasms, Experimental; Rats; Rats, Inbred F344; Species Specificity

1999
1,3-butadiene: cancer, mutations, and adducts. Part I: Carcinogenicity of 1,2,3,4-diepoxybutane.
    Research report (Health Effects Institute), 2000, Issue:92

    Topics: Administration, Inhalation; Animals; Butadienes; Carcinogenicity Tests; Carcinogens; DNA Adducts; Epoxy Compounds; Female; Genes, ras; Mice; Mutagens; Mutation; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley

2000
1,3-butadiene: cancer, mutations, and adducts. Part IV: Molecular dosimetry of 1,3-butadiene.
    Research report (Health Effects Institute), 2000, Issue:92

    Topics: Animals; Biomarkers; Butadienes; Carcinogens; Cattle; Cell Line; Chromatography, Liquid; DNA Adducts; Dose-Response Relationship, Drug; Humans; Mass Spectrometry; Mice; Mutagens; Mutation; Neoplasms, Experimental; Rats; Rats, Inbred F344

2000
1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
    Research report (Health Effects Institute), 2000, Issue:92

    Topics: Animals; Animals, Genetically Modified; Bacterial Proteins; Base Sequence; Butadienes; Carcinogens; DNA; DNA Adducts; DNA Mutational Analysis; Escherichia coli Proteins; Humans; Hypoxanthine Phosphoribosyltransferase; Lac Repressors; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasms, Experimental; Rats; Rats, Inbred F344; Repressor Proteins

2000
1,3-butadiene: cancer, mutations, and adducts. Part III: In vivo mutation of the endogenous hprt genes of mice and rats by 1,3-butadiene and its metabolites.
    Research report (Health Effects Institute), 2000, Issue:92

    Topics: Animals; Butadienes; Carcinogens; DNA Adducts; Female; Humans; Hypoxanthine Phosphoribosyltransferase; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasms, Experimental; Rats

2000
1,3-butadiene: cancer, mutations, and adducts. Part V: Hemoglobin adducts as biomarkers of 1,3-butadiene exposure and metabolism.
    Research report (Health Effects Institute), 2000, Issue:92

    Topics: Animals; Biomarkers; Butadienes; Calibration; Carcinogenicity Tests; Carcinogens; DNA Adducts; Female; Hemoglobins; Humans; Male; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Reference Standards

2000
Carcinogenicity of butadiene.
    Science (New York, N.Y.), 1992, Sep-04, Volume: 257, Issue:5075

    Topics: Animals; Butadienes; Humans; Mice; Neoplasms, Experimental; Occupational Diseases; Rats

1992
Carcinogenicity of butadiene.
    Science (New York, N.Y.), 1992, Sep-04, Volume: 257, Issue:5075

    Topics: Animals; Butadienes; Humans; Mice; Neoplasms, Experimental; Occupational Diseases; Rats

1992
Carcinogenicity of 1,3-butadiene in C57BL/6 x C3H F1 mice at low exposure concentrations.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Butadienes; Dose-Response Relationship, Drug; Female; Heart Neoplasms; Hemangiosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Stomach Neoplasms

1990
Future directions in epidemiologic studies of 1,3-butadiene-exposed workers.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Animals; Butadienes; Carcinogenicity Tests; Chemical Industry; Cohort Studies; Follow-Up Studies; Humans; Lymphoma; Neoplasms, Experimental; Occupational Diseases; Risk Factors

1990
OSHA's approach to risk assessment for setting a revised occupational exposure standard for 1,3-butadiene.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Air Pollutants, Occupational; Animals; Butadienes; Carcinogens; Environmental Exposure; Female; Humans; Male; Mice; Neoplasms; Neoplasms, Experimental; Occupational Diseases; Rats; Risk Factors; United States; United States Occupational Safety and Health Administration

1990
Inhalation toxicity and carcinogenicity of 1,3-butadiene in Sprague-Dawley rats.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Air Pollutants, Occupational; Animals; Butadienes; Carcinogens; Female; Kidney; Male; Neoplasms, Experimental; Neuromuscular Junction; Organ Size; Rats; Rats, Inbred Strains

1990
Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Air Pollutants, Occupational; Animals; Blood Cells; Body Weight; Butadienes; Carcinogens; Female; Male; Mice; Neoplasms, Experimental; Organ Size; Time Factors

1990
Morphology of neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice.
    Environmental health perspectives, 1990, Volume: 86

    Topics: Animals; Butadienes; Carcinogens; Female; Heart Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Ovarian Neoplasms; Stomach Neoplasms

1990
Neoplastic lesions induced by 1,3-butadiene in B6C3F1 mice.
    Experimental pathology, 1989, Volume: 37, Issue:1-4

    Topics: Adenocarcinoma; Adenoma; Animals; Butadienes; Carcinoma; Female; Granulosa Cell Tumor; Heart Neoplasms; Hemangiosarcoma; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mice; Mutagens; Neoplasms, Experimental; Ovarian Neoplasms; Stomach Neoplasms

1989