Page last updated: 2024-08-26

1,3,4-oxadiazole and Disease Models, Animal

1,3,4-oxadiazole has been researched along with Disease Models, Animal in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Chen, YL; Duan, YJ; Li, QS; Liu, ZG; Meng, HW; Meng, XS; Shen, ZB; Wang, TX; Wang, XR; Yang, XX; Yin, ZQ; Zhang, S; Zou, TF1
Choubey, PK; Seth, A; Shrivastava, SK; Tripathi, A; Tripathi, MK1
Bader, M; Celik, T; Dedeoglu-Erdogan, A; Gurdal, EE; Koksal, M; Ozgurbuz, M; Reis, R; Sipahi, H; Sippl, W1
Alam, MS; Dhulap, A; Hamid, H; Kalam, A; Khan, I; Tantray, MA1
Bhutani, R; Husain, A; Iqbal, MA; Kapoor, G; Pathak, DP1
Baev, DS; Frolova, TS; Popov, SA; Semenova, MD; Shults, EE; Sorokina, IV; Tolstikova, TG; Turks, M; Zhukova, NA1
Banerjee, AG; Das, N; Shengule, SA; Shrivastava, SK; Srivastava, RS1

Other Studies

7 other study(ies) available for 1,3,4-oxadiazole and Disease Models, Animal

ArticleYear
Novel flavonoid 1,3,4-oxadiazole derivatives ameliorate MPTP-induced Parkinson's disease via Nrf2/NF-κB signaling pathway.
    Bioorganic chemistry, 2023, Volume: 138

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Flavonoids; Inflammation; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Parkinson Disease; Signal Transduction

2023
Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer's disease.
    Bioorganic chemistry, 2021, Volume: 111

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Male; Maze Learning; Molecular Structure; Neuroprotective Agents; Oxadiazoles; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Structure-Activity Relationship

2021
Design, synthesis, and molecular docking of novel 3,5-disubstituted-1,3,4-oxadiazole derivatives as iNOS inhibitors.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Edema; Enzyme Inhibitors; Indomethacin; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Nitric Oxide Synthase Type II; Oxadiazoles; RAW 264.7 Cells; Structure-Activity Relationship

2021
Synthesis of benzimidazole-linked-1,3,4-oxadiazole carboxamides as GSK-3β inhibitors with in vivo antidepressant activity.
    Bioorganic chemistry, 2018, Volume: 77

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glycogen Synthase Kinase 3 beta; Hindlimb Suspension; Humans; Male; Molecular Dynamics Simulation; Molecular Structure; Oxadiazoles; Rats; Rats, Wistar; Recombinant Proteins; Structure-Activity Relationship

2018
Novel hybrids of benzothiazole-1,3,4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment.
    Bioorganic chemistry, 2019, Volume: 83

    Topics: Administration, Oral; Animals; Benzothiazoles; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Hypoglycemic Agents; Male; Molecular Docking Simulation; Molecular Structure; Oxadiazoles; Rats; Rats, Wistar; Streptozocin; Structure-Activity Relationship; Thiazolidines

2019
Lupane-type conjugates with aminoacids, 1,3,4- oxadiazole and 1,2,5-oxadiazole-2-oxide derivatives: Synthesis, anti-inflammatory activity and in silico evaluation of target affinity.
    Steroids, 2019, Volume: 150

    Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Computer Simulation; Concanavalin A; Disease Models, Animal; Edema; Female; Fibroblasts; Histamine; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-kappa B; Oxadiazoles; Triterpenes

2019
Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2015, Aug-28, Volume: 101

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Kinetics; Mice; Molecular Dynamics Simulation; Molecular Structure; Oxadiazoles; Pain; Rats; Stomach Ulcer; Structure-Activity Relationship; Triazines

2015