1-3--diethyl-4-2--quinolylthiacyanine-iodide has been researched along with Disease-Models--Animal* in 1 studies
1 other study(ies) available for 1-3--diethyl-4-2--quinolylthiacyanine-iodide and Disease-Models--Animal
| Article | Year |
|---|---|
Inhibitory Effect of Multimodal Nanoassemblies against Glycative and Oxidative Stress in Cancer and Glycation Animal Models.
In recent years, there has been a progress in the study of glycation reaction which is one the possible reason for multiple metabolic disorders. Glycation is a nonenzymatic reaction between nucleic acids, lipids, and proteins resulting into the formation of early glycation products that may further lead to the accumulation of advanced glycation end products (AGEs). The precipitation of AGEs in various cells, tissues, and organs is one of the factors for the initiation and progression of various metabolic derangements including the cancer. The AGE interaction with its receptor "RAGE" activates the inflammatory pathway; yet, the downregulation of RAGE and its role in these pathways are not clear. We explore the effect of anticancer novel nanoassemblies on AGEs to determine its role in the regulation of the expression of RAGE, NFƙB, TNF- Topics: A549 Cells; Animals; Benzothiazoles; Blood Glucose; Carbocyanines; Cell Proliferation; Disease Models, Animal; Glycosylation; Humans; Interferon-gamma; Lung Neoplasms; MCF-7 Cells; Mice; Models, Biological; Nanoparticles; NF-kappa B; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Serum Albumin, Human; Spectrophotometry; Trifluridine; Tumor Necrosis Factor-alpha | 2021 |