Compounds > 1-2-oleoylphosphatidylcholine

1-2-oleoylphosphatidylcholine and Liver-Neoplasms

1-2-oleoylphosphatidylcholine has been researched along with Liver-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 1-2-oleoylphosphatidylcholine and Liver-Neoplasms

Article	Year
Peptide density targets and impedes triple negative breast cancer metastasis. Nature communications, 2018, 07-04, Volume: 9, Issue:1 The C-X-C chemokine receptor type 4 (CXCR4, CD184) pathway is a key regulator of cancer metastasis. Existing therapeutics that block CXCR4 signaling are dependent on single molecule-receptor interactions or silencing CXCR4 expression. CXCR4 localizes in lipid rafts and forms dimers therefore CXCR4 targeting and signaling may depend on ligand density. Herein, we report liposomes presenting a CXCR4 binding peptide (DV1) as a three-dimensional molecular array, ranging from 9k to 74k molecules μm Topics: Animals; Antineoplastic Agents; Binding, Competitive; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression; Genes, Reporter; Humans; Liposomes; Liver Neoplasms; Luciferases; Lung Neoplasms; Membrane Microdomains; Mice; Mice, Nude; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Protein Binding; Receptors, CXCR4; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays	2018

Article

Year

Peptide density targets and impedes triple negative breast cancer metastasis.

Nature communications, 2018, 07-04, Volume: 9, Issue:1

The C-X-C chemokine receptor type 4 (CXCR4, CD184) pathway is a key regulator of cancer metastasis. Existing therapeutics that block CXCR4 signaling are dependent on single molecule-receptor interactions or silencing CXCR4 expression. CXCR4 localizes in lipid rafts and forms dimers therefore CXCR4 targeting and signaling may depend on ligand density. Herein, we report liposomes presenting a CXCR4 binding peptide (DV1) as a three-dimensional molecular array, ranging from 9k to 74k molecules μm

Topics: Animals; Antineoplastic Agents; Binding, Competitive; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression; Genes, Reporter; Humans; Liposomes; Liver Neoplasms; Luciferases; Lung Neoplasms; Membrane Microdomains; Mice; Mice, Nude; Peptides; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Protein Binding; Receptors, CXCR4; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2018