1-2-oleoylphosphatidylcholine and Amyotrophic-Lateral-Sclerosis

1-2-oleoylphosphatidylcholine has been researched along with Amyotrophic-Lateral-Sclerosis* in 1 studies

Other Studies

1 other study(ies) available for 1-2-oleoylphosphatidylcholine and Amyotrophic-Lateral-Sclerosis

ArticleYear
Glycerolipid Headgroups Control Rate and Mechanism of Superoxide Dismutase-1 Aggregation and Accelerate Fibrillization of Slowly Aggregating Amyotrophic Lateral Sclerosis Mutants.
    ACS chemical neuroscience, 2018, 07-18, Volume: 9, Issue:7

    Interactions between superoxide dismutase-1 (SOD1) and lipid membranes might be directly involved in the toxicity and intercellular propagation of aggregated SOD1 in amyotrophic lateral sclerosis (ALS), but the chemical details of lipid-SOD1 interactions and their effects on SOD1 aggregation remain unclear. This paper determined the rate and mechanism of nucleation of fibrillar apo-SOD1 catalyzed by liposomal surfaces with identical hydrophobic chains (RCH

    Topics: Amyotrophic Lateral Sclerosis; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Phosphatidylcholines; Protein Aggregation, Pathological; Recombinant Proteins; Saccharomyces cerevisiae; Superoxide Dismutase-1; Surface Properties

2018