1,2-dioctanoylglycerol has been researched along with Myocardial Ischemia in 6 studies
1,2-dioctanoylglycerol: functions as bioregulator of protein kinase C in human platelets
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Speechly-Dick, ME | 2 |
| Grover, GJ | 1 |
| Yellon, DM | 4 |
| Mocanu, MM | 2 |
| Baxter, GF | 1 |
| Rohs, TJ | 1 |
| Kilgore, KS | 1 |
| Georges, AJ | 1 |
| Bolling, SF | 1 |
| Tani, M | 1 |
| Honma, Y | 1 |
| Hasegawa, H | 1 |
| Tamaki, K | 1 |
| Schulman, D | 1 |
| Latchman, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Eplerenone on Ischemia Reperfusion Injury in Human Myocardium (EPLICARD Study)[NCT02118753] | 24 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for 1,2-dioctanoylglycerol and Myocardial Ischemia
| Article | Year |
|---|---|
Does ischemic preconditioning in the human involve protein kinase C and the ATP-dependent K+ channel? Studies of contractile function after simulated ischemia in an atrial in vitro model.
Topics: Adenosine Triphosphate; Adult; Aged; Alkaloids; Benzophenanthridines; Benzopyrans; Cromakalim; Digly | 1995 |
Protein kinase C. Its role in ischemic preconditioning in the rat.
Topics: Alkaloids; Analysis of Variance; Animals; Arrhythmias, Cardiac; Benzophenanthridines; Blood Pressure | 1994 |
Attenuation of myocardial ischaemic injury 24 h after diacylglycerol treatment in vivo.
Topics: Animals; Blood Pressure; Diglycerides; Enzyme Activation; Heart Rate; Heat-Shock Proteins; Hemodynam | 1997 |
Postischemic function and protein kinase C signal transduction.
Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Bicarbonates; Calcium Chloride; Cardioplegi | 1998 |
Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts.
Topics: Aging; Animals; Anti-Arrhythmia Agents; Creatine Kinase; Decanoic Acids; Diglycerides; Heart; Hydrox | 2001 |
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury.
Topics: Adenosine; Aging; Animals; Diazoxide; Diglycerides; Heart; Ischemic Preconditioning, Myocardial; Mal | 2001 |