1,2-dimethylhydrazine has been researched along with Pregnancy in 11 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The modifying effect of pregnancy and lactation on carcinogenesis induced by single injection of 1,2-dimethylhydrazine to female rats 30 days before mating has been studied." | 7.68 | [Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats]. ( Blinova, GA; Mikheev, AM; Napalkov, NP, 1990) |
| "CBA female mice, at the 17th day of pregnancy, received single intraperitoneal injection of diethylstilbestrol (DES) at the dose of 1 mg/kg body weight (b." | 3.70 | 1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol. ( Samoilov, D; Trukhanova, L; Turusov, V, 2000) |
| ") of diethylstilbestrol (DES) at day 17 of pregnancy." | 3.69 | 1,2-Dimethylhydrazine carcinogenesis in C3HA and CBA female mice prenatally treated with diethylstilbestrol. ( Gorbacheva, EV; Lanko, NS; Morozova, OV; Politova, SN; Trukhanova, LS; Turusov, VS, 1997) |
| "The modifying effect of pregnancy and lactation on carcinogenesis induced by single injection of 1,2-dimethylhydrazine to female rats 30 days before mating has been studied." | 3.68 | [Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats]. ( Blinova, GA; Mikheev, AM; Napalkov, NP, 1990) |
| "Nephroblastomas were induced at an early age in two of six cynomolgus monkeys by prenatal exposure to 1,2-dimethylhydrazine." | 1.28 | Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine. ( Beniashvili, DS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alderman, JA | 1 |
| Walden, R | 1 |
| Schiller, CM | 1 |
| Stevens, RH | 1 |
| Cole, DA | 1 |
| Keller, WC | 1 |
| Olson, CT | 1 |
| Back, KC | 1 |
| Gaworski, CL | 1 |
| Likhachev, AIa | 1 |
| Petrov, AS | 1 |
| Turusov, VS | 1 |
| Trukhanova, LS | 1 |
| Lanko, NS | 1 |
| Morozova, OV | 1 |
| Gorbacheva, EV | 1 |
| Politova, SN | 1 |
| Turusov, V | 1 |
| Trukhanova, L | 1 |
| Samoilov, D | 1 |
| Napalkov, NP | 1 |
| Mikheev, AM | 1 |
| Blinova, GA | 1 |
| Beniashvili, DS | 1 |
| Beniashvili, DSh | 1 |
| Sýkora, I | 1 |
| Vortel, V | 1 |
| Tretiník, P | 1 |
| Quaroni, A | 1 |
| Weiser, MM | 1 |
| Lee, S | 1 |
| Amodeo, D | 1 |
11 other studies available for 1,2-dimethylhydrazine and Pregnancy
| Article | Year |
|---|---|
Development of rat liver and colon substrate cycle enzymes in offspring with and without prenatal exposure to a carcinogenic dose of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; Dimethylhydrazines; Enzyme Induction; Female; Li | 1983 |
Identification of carcinogens by measurement of cell-mediated immunity. IV. Antitumor immunity following perinatal exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Cytotoxicity, Immuno | 1983 |
Teratogenic assessment of three methylated hydrazine derivatives in the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Dimethylhydrazines; Female; Fetal Resorption; Injection | 1984 |
[DNA methylation characteristics of different fetal and maternal body tissues in rats administered 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenine; Animals; Dimethylhydrazines; DNA; Female; Fetus; Guanine; Methylatio | 1981 |
1,2-Dimethylhydrazine carcinogenesis in C3HA and CBA female mice prenatally treated with diethylstilbestrol.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Diethylstilbestrol; Dimethylhydrazines; Estrogens, Non- | 1997 |
1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Diethylstilbestrol; Female; I | 2000 |
[Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Colonic Neoplasms; Dimethylhydra | 1990 |
Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney Neoplasms; Macaca fa | 1989 |
[Induction of renal tumors in monkeys as a result of probable prenatal effects of 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney; Kidney Neoplasms; M | 1989 |
Postnatal carcinogenic study of 1,2-dimethylhydrazine dihydrochloride in rats.
Topics: 1,2-Dimethylhydrazine; Adenoma, Bile Duct; Animals; Dimethylhydrazines; Female; Hemangioma, Cavernou | 1986 |
Expression of developmentally regulated crypt cell antigens in human and rat intestinal tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens; Carcinoembryonic A | 1986 |