1,2-dimethylhydrazine has been researched along with Peritoneal Neoplasms in 3 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Peritoneal Neoplasms: Tumors or cancer of the PERITONEUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fischer F344 rats receiving 20mg/kg of 1,2-dimethylhydrazine per week for 20 weeks developed adenocarcinoma of the colon." | 3.68 | [Establishment of a transplantable rat colon cancer and a model of metastasis]. ( Yasuda, S, 1993) |
| "Peritoneal carcinomatosis, a common spreading of human colon carcinoma, can be obtained by intraperitoneal injection of colon tumor cells in rats." | 1.27 | Treatment with endotoxins of peritoneal carcinomatosis induced by colon tumor cells in the rat. ( Jeannin, JF; Lagadec, P; Olsson, O; Pelletier, H; Reisser, D, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Metzger, U | 1 |
| Meier, J | 1 |
| Uhlschmid, G | 1 |
| Weihe, H | 1 |
| Yasuda, S | 1 |
| Lagadec, P | 1 |
| Jeannin, JF | 1 |
| Reisser, D | 1 |
| Pelletier, H | 1 |
| Olsson, O | 1 |
3 other studies available for 1,2-dimethylhydrazine and Peritoneal Neoplasms
| Article | Year |
|---|---|
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating | 1984 |
[Establishment of a transplantable rat colon cancer and a model of metastasis].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cell Division; Colonic Neoplasms; Dimethylhydrazines | 1993 |
Treatment with endotoxins of peritoneal carcinomatosis induced by colon tumor cells in the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinoma; Colonic Neoplasms; Dimethylhydrazines; Endotoxins; Female | 1987 |