Page last updated: 2024-10-21

1,2-dimethylhydrazine and Obesity

1,2-dimethylhydrazine has been researched along with Obesity in 3 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Obesity has recently become a focus of research to elucidate diet and lifestyle factors as important risk factors for colon cancer."1.34Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine. ( Arthur, JR; Barrera, LN; Drew, JE; Duthie, GG; Farquharson, AJ; Mercer, JG; Morrice, PC; Padidar, S, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Subarmaniam, T1
Mahmad Rusli, RN1
Perumal, KV1
Yong, YK1
Hadizah, S1
Othman, F1
Salem, K1
Shafie, NH1
Hasham, R1
Yin, KB1
Abdul Kadir, KK1
Bahari, H1
Zakaria, ZA1
Drew, JE1
Farquharson, AJ1
Padidar, S1
Duthie, GG1
Mercer, JG1
Arthur, JR1
Morrice, PC1
Barrera, LN1
Koch, TC1
Briviba, K1
Watzl, B1
Bub, A1
Barth, SW1

Other Studies

3 other studies available for 1,2-dimethylhydrazine and Obesity

ArticleYear
The Potential Chemopreventive Effect of
    International journal of molecular sciences, 2023, Mar-09, Volume: 24, Issue:6

    Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Andrographis paniculata; Animals; Anticarcinogenic Agent

2023
Insulin, leptin, and adiponectin receptors in colon: regulation relative to differing body adiposity independent of diet and in response to dimethylhydrazine.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:4

    Topics: 1,2-Dimethylhydrazine; Adiponectin; Adipose Tissue; Animals; Colon; Male; Obesity; Rats; Rats, Sprag

2007
Obesity-related promotion of aberrant crypt foci in DMH-treated obese Zucker rats correlates with dyslipidemia rather than hyperinsulinemia.
    European journal of nutrition, 2008, Volume: 47, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Caloric Restriction; Cell Division; Colonic Neoplasms; Comet Assay;

2008