1,2-dimethylhydrazine has been researched along with Neoplasms in 7 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "CBA female mice, at the 17th day of pregnancy, received single intraperitoneal injection of diethylstilbestrol (DES) at the dose of 1 mg/kg body weight (b." | 3.70 | 1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol. ( Samoilov, D; Trukhanova, L; Turusov, V, 2000) |
| "A striking anticancer effect of IP6 was demonstrated in different experimental models." | 2.42 | Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. ( Shamsuddin, AM; Vucenik, I, 2003) |
| "Further studies on fresh human tumors were conducted with a novel topoisomerase II inhibitor, NC-190." | 1.33 | Image analysis using the fluorochromasia assay to quantify tumor drug sensitivity. ( Gibbs, JF; Rustum, YM; Slocum, HK, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vucenik, I | 1 |
| Shamsuddin, AM | 1 |
| Popovich, IG | 1 |
| Zabezhinski, MA | 1 |
| Egormin, PA | 1 |
| Tyndyk, ML | 1 |
| Anikin, IV | 1 |
| Spasov, AA | 1 |
| Semenchenko, AV | 1 |
| Yashin, AI | 1 |
| Anisimov, VN | 1 |
| Gibbs, JF | 1 |
| Rustum, YM | 1 |
| Slocum, HK | 1 |
| Turusov, V | 1 |
| Trukhanova, L | 1 |
| Samoilov, D | 1 |
| Avivi-Green, C | 1 |
| Polak-Charcon, S | 1 |
| Madar, Z | 1 |
| Schwartz, B | 1 |
| Kimoto, N | 1 |
| Hirose, M | 1 |
| Futakuchi, M | 1 |
| Iwata, T | 1 |
| Kasai, M | 1 |
| Shirai, T | 1 |
| Stevens, RH | 1 |
| Cole, DA | 1 |
| Lindholm, PA | 1 |
| Cheng, HF | 1 |
1 review available for 1,2-dimethylhydrazine and Neoplasms
| Article | Year |
|---|---|
Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Colonic Neoplasms; Disease Mod | 2003 |
6 other studies available for 1,2-dimethylhydrazine and Neoplasms
| Article | Year |
|---|---|
Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
Topics: 1,2-Dimethylhydrazine; Age Factors; Aging; Animals; Anticarcinogenic Agents; Benzimidazoles; Body Te | 2005 |
Image analysis using the fluorochromasia assay to quantify tumor drug sensitivity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antineoplastic Agents; Biopsy; Cell Survival; Coloni | 2005 |
1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Diethylstilbestrol; Female; I | 2000 |
Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Body Weight; Butyr | 2000 |
Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Butylhydroxybutylnitr | 2001 |
Identification of environmental carcinogens utilizing T-cell mediated immunity.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Carcinogens, Environment | 1986 |