1,2-dimethylhydrazine has been researched along with Kidney Neoplasms in 33 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The modifying effect of pregnancy and lactation on carcinogenesis induced by single injection of 1,2-dimethylhydrazine to female rats 30 days before mating has been studied." | 7.68 | [Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats]. ( Blinova, GA; Mikheev, AM; Napalkov, NP, 1990) |
| "CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 7.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
| "CBA female mice, at the 17th day of pregnancy, received single intraperitoneal injection of diethylstilbestrol (DES) at the dose of 1 mg/kg body weight (b." | 3.70 | 1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol. ( Samoilov, D; Trukhanova, L; Turusov, V, 2000) |
| "The modifying effect of pregnancy and lactation on carcinogenesis induced by single injection of 1,2-dimethylhydrazine to female rats 30 days before mating has been studied." | 3.68 | [Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats]. ( Blinova, GA; Mikheev, AM; Napalkov, NP, 1990) |
| "Pararenal angiosarcomas appear in CBA male mice treated with 1,2-dimethylhydrazine (DMH)." | 3.67 | [Effect of sex hormones on the induction of renal capsule angiosarcomas in mice]. ( Chemeris, GIu, 1989) |
| "CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 3.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
| "The effect of long-term administration of the novel maleimide derivative with antiproliferative activity on kidney morpho-functional state in experimental (1,2-dimethylhydrazine-induced) colon carcinogenesis has been investigated on 60 male rats." | 1.36 | [Effect of maleimide derivative on the morpho-functional state of the kidney in experimental colon carcinogenesis in rats]. ( Filins'ka, OM; Iablons'ka, SV; Kharchuk, IV; Rybal'chenko, VK, 2010) |
| " Treatments were begun 8 days post-operative and 17 days later, the single dosage of DMH as in the above was injected." | 1.29 | Tumors produced in rats with a single dosage of 1,2-dimethylhydrazine. ( Amir-Mokri, E; Brown, ME; Gershbein, LL; Rezai, VK, 1993) |
| " The dose-response study shows a sharp increase (from 5 to 75%) of the epithelial renal tumour incidence in the range of 2, 4 and 8 injections of DMH." | 1.28 | [1,2-dimethylhydrazine induction of epithelial tumors of the kidneys in CBA strain mice]. ( Chemeris, GIu; Lanko, NS; Parfenov, IuD; Turusov, VS, 1990) |
| "Nephroblastomas were induced at an early age in two of six cynomolgus monkeys by prenatal exposure to 1,2-dimethylhydrazine." | 1.28 | Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine. ( Beniashvili, DS, 1989) |
| "Indomethacin was given orally to 40 of the rats." | 1.28 | Effect of indomethacin in autotransplanted colonic tumors. ( Duvander, A; Rubio, CA; Sveander, M; Wallin, B; Ware, J, 1989) |
| "This pathological resemblance to human nephroblastoma suggests the possibility of using dimethylhydrazine-induced renal tumours as a model of Wilms' tumour." | 1.27 | Induction of nephroblastoma-like renal tumours in rats by a single dose of 1,2-dimethylhydrazine. ( Cruse, JP; Lewin, MR; Sadrudin, AA, 1985) |
| " In a lifetime study with the CBA strain, groups of 19-30 animals of each sex were dosed s." | 1.27 | Carcinogenicity of deuterium-labeled 1,2-dimethylhydrazine in mice. ( Gordon, WP; Hillery, PS; Keefer, LK; Lanko, NS; Nelson, SD; Parfenov, YD; Turusov, VS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (45.45) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morozova, OV | 2 |
| Karamysheva, AF | 1 |
| Shavochkina, DA | 1 |
| Trukhanova, LS | 2 |
| Turusov, VS | 12 |
| Kharchuk, IV | 1 |
| Filins'ka, OM | 1 |
| Iablons'ka, SV | 1 |
| Rybal'chenko, VK | 1 |
| Pliss, GB | 1 |
| Mel'nikov, AS | 1 |
| Malinin, VV | 1 |
| Khavinson, VKh | 1 |
| McConnell, EE | 1 |
| Rutter, HA | 1 |
| Ulland, BM | 1 |
| Moore, JA | 1 |
| Toth, B | 1 |
| Patil, K | 1 |
| Sunter, JP | 1 |
| Senior, PV | 1 |
| Chemeris, GIu | 5 |
| Akagi, K | 3 |
| Hirose, M | 4 |
| Hoshiya, T | 2 |
| Mizoguchi, Y | 1 |
| Ito, N | 3 |
| Shirai, T | 2 |
| Yada, H | 1 |
| Hakoi, K | 1 |
| Takahashi, S | 3 |
| Hara, Y | 1 |
| Gershbein, LL | 1 |
| Amir-Mokri, E | 1 |
| Rezai, VK | 1 |
| Brown, ME | 1 |
| Kondalenko, VF | 2 |
| Kimura, J | 1 |
| Ogiso, T | 1 |
| Yoshida, Y | 1 |
| Hasegawa, R | 1 |
| Kurata, M | 1 |
| Samoĭlov, DV | 1 |
| Turusov, V | 1 |
| Trukhanova, L | 1 |
| Samoilov, D | 1 |
| Colussi, C | 1 |
| Fiumicino, S | 1 |
| Giuliani, A | 1 |
| Rosini, S | 1 |
| Musiani, P | 1 |
| Macrí, C | 1 |
| Potten, CS | 1 |
| Crescenzi, M | 1 |
| Bignami, M | 1 |
| Napalkov, NP | 1 |
| Mikheev, AM | 1 |
| Blinova, GA | 1 |
| Lanko, NS | 2 |
| Parfenov, IuD | 1 |
| Pozharisskiĭ, KM | 1 |
| Kyshtoobaeva, ASh | 1 |
| Klimashevskiĭ, VF | 1 |
| Beniashvili, DS | 1 |
| Beniashvili, DSh | 1 |
| Daniel, FB | 1 |
| DeAngelo, AB | 1 |
| Stober, JA | 1 |
| Pereira, MA | 1 |
| Olson, GR | 1 |
| Rubio, CA | 1 |
| Wallin, B | 1 |
| Ware, J | 1 |
| Sveander, M | 1 |
| Duvander, A | 1 |
| Sadrudin, AA | 1 |
| Lewin, MR | 1 |
| Cruse, JP | 1 |
| Sýkora, I | 1 |
| Vortel, V | 1 |
| Tretiník, P | 1 |
| Parfenov, YD | 2 |
| Gordon, WP | 1 |
| Nelson, SD | 1 |
| Hillery, PS | 1 |
| Keefer, LK | 1 |
| Smirnova, IO | 1 |
| Chemeris, GY | 1 |
33 other studies available for 1,2-dimethylhydrazine and Kidney Neoplasms
| Article | Year |
|---|---|
[Expression of VEGFA during 1,2-dimethylhydrazine induction of malignant hemangioendothelioma in the renal capsule in mice].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Gene Expression Regulation, Neoplastic; Hemangioendothe | 2013 |
[Influence of dichlorodiphenyldichloroethylene on 1,2 dimethylhydrazine-induced androgen-dependent renal capsule angiosarcoma development].
Topics: 1,2-Dimethylhydrazine; Androgen Antagonists; Androgens; Animals; Carcinogens; Dichlorodiphenyl Dichl | 2008 |
[Effect of maleimide derivative on the morpho-functional state of the kidney in experimental colon carcinogenesis in rats].
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Antineoplastic Agents; Cell Proliferation; Col | 2010 |
[The effect of vilon (Lys-Glu) on 1.2-dimethylhydrazine-induced neoplasia].
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Dipeptides; Kidney Neoplasms; Mice; Precanc | 2005 |
Chronic effects of dietary exposure to amosite asbestos and tremolite in F344 rats.
Topics: 1,2-Dimethylhydrazine; Animals; Asbestos; Asbestos, Amosite; Asbestos, Amphibole; Body Weight; Cocar | 1983 |
Enhancing effect of vitamin E on murine intestinal tumorigenesis by 1,2-dimethylhydrazine dihydrochloride.
Topics: 1,2-Dimethylhydrazine; Anal Gland Neoplasms; Animals; Cecal Neoplasms; Colonic Neoplasms; Diet; Dime | 1983 |
Role of host factors in carcinogenesis induced in mice by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Hemangiosarcoma; Hemorrhage | 1983 |
Induction of renal tumours in rats by the administration of 1,2 dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Injections, Subcutaneous; K | 1983 |
[Effect of castration and mouse strain on 1, 2-dimethylhydrazine induction of pararenal angiosarcomas and kidney adenomas].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Castration; Dimethylhydrazines; Hemangiosarcoma; Kidney Neo | 1982 |
Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Benzaldehydes; Butylhydroxybutylnitrosamine; Diethylnitrosamine; Dim | 1995 |
Modification of carcinogenesis by alpha-tocopherol, t-butylhydroquinone, propyl gallate and butylated hydroxytoluene in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Butylated Hydroxytoluene; Car | 1993 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitr | 1993 |
Tumors produced in rats with a single dosage of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1993 |
[Ultrastructure of renal-cell tumors induced in mice by 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Renal Cell; Dime | 1995 |
Lack of chemoprevention effects of the monoterpene d-limonene in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carc | 1996 |
Renal cell tumours in mice: electron microscopy versus immunohistochemistry.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Biomarkers, Tumor; Dimethylhydrazines; gamma-Glutamyltransf | 1997 |
[Effect of prenatal treatment with diethylstilbestrol on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA mice].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Diethylstilbestrol; Kidney | 1998 |
1,2-Dimethylhydrazine carcinogenesis in CBA male mice prenatally treated with diethylstilbestrol.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinoma; Colonic Neoplasms; Diethylstilbestrol; Female; I | 2000 |
1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alkylating Agents; Animals; Apoptosis; Base Pair Mismatch; Ca | 2001 |
Renal cell tumors induced in CBA male mice by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma, Renal Cell; Dimethylhydrazines; gam | 1992 |
[Modifying effects of changes connected with pregnancy on 1,2-dimethylhydrazine-induced carcinogenesis in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Colonic Neoplasms; Dimethylhydra | 1990 |
[1,2-dimethylhydrazine induction of epithelial tumors of the kidneys in CBA strain mice].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Carcinoma; Cystadenocarcinoma; Dimethylhydrazi | 1990 |
[Morphogenesis and histogenesis of experimental malignant hemangioendothelioma].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Hemangioendothelioma; Kidney; Kidne | 1990 |
Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney Neoplasms; Macaca fa | 1989 |
[Induction of renal tumors in monkeys as a result of probable prenatal effects of 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney; Kidney Neoplasms; M | 1989 |
[Effect of sex hormones on the induction of renal capsule angiosarcomas in mice].
Topics: 1,2-Dimethylhydrazine; Animals; Castration; Dimethylhydrazines; Drug Interactions; Estradiol; Female | 1989 |
Chloroform inhibition of 1,2-dimethylhydrazine-induced gastrointestinal tract tumors in the Fisher 344 rat.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Chloroform; Dimethylhydrazines; Gastrointestin | 1989 |
Effect of indomethacin in autotransplanted colonic tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1989 |
Induction of nephroblastoma-like renal tumours in rats by a single dose of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Disease Models, Animal; Female; Kid | 1985 |
Postnatal carcinogenic study of 1,2-dimethylhydrazine dihydrochloride in rats.
Topics: 1,2-Dimethylhydrazine; Adenoma, Bile Duct; Animals; Dimethylhydrazines; Female; Hemangioma, Cavernou | 1986 |
Carcinogenicity of deuterium-labeled 1,2-dimethylhydrazine in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Biotransformation; Carcinogens; Colonic Neoplasms; Deuterium; Dimeth | 1988 |
[Modifying action of neonatal androgenization on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA-strain mice].
Topics: 1,2-Dimethylhydrazine; Animals; Animals, Newborn; Dimethylhydrazines; Hemangiosarcoma; Intestinal Ne | 1985 |
Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Androgens; Animals; Carcinogens; Castration; Colonic Neoplasms; Dime | 1985 |