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1,2-dimethylhydrazine and Intestinal Polyps

1,2-dimethylhydrazine has been researched along with Intestinal Polyps in 2 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.

Research Excerpts

ExcerptRelevanceReference
" Because dosage schedules are known from previous experiments with the Nb rat, this animal model may be useful for evaluating the effects of cytotoxic drugs on experimental bowel cancer."1.27Experimental cancer of the bowel in the Nb rat. ( Drago, JR; Joehl, RJ, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joehl, RJ1
Drago, JR1
Krutovskikh, VA1
Turusov, VS1

Other Studies

2 other studies available for 1,2-dimethylhydrazine and Intestinal Polyps

ArticleYear
Experimental cancer of the bowel in the Nb rat.
    Journal of surgical oncology, 1983, Volume: 24, Issue:2

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Disease Model

1983
[Morphogenesis of experimental cancer of the large intestine (according to the results of scanning electron and light microscopy)].
    Arkhiv patologii, 1982, Volume: 44, Issue:9

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhyd

1982