1,2-dimethylhydrazine has been researched along with Inflammatory Bowel Diseases in 2 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carcinoma was found in both the prolonged reactivation and saline-DMH groups." | 1.34 | Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer. ( Appleyard, CB; Isidro, AA; Pagán, B; Santiago, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santiago, C | 1 |
| Pagán, B | 1 |
| Isidro, AA | 1 |
| Appleyard, CB | 1 |
| Meenan, J | 1 |
2 other studies available for 1,2-dimethylhydrazine and Inflammatory Bowel Diseases
| Article | Year |
|---|---|
Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenomatous Polyposis Coli Protein; Animals; Carcinoma; Chronic Disease; Coli | 2007 |
Co-carcinogenic effect of sulphasalazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cocarcinogenesis; Dimethylhydrazines; Folic Acid Defici | 1993 |