1,2-dimethylhydrazine has been researched along with Genetic Predisposition in 8 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Pace, RF | 1 |
| Massa, S | 1 |
| Ribeiro, OG | 1 |
| Cabrera, WH | 1 |
| De Franco, M | 1 |
| Starobinas, N | 1 |
| Seman, M | 1 |
| Ibañez, OC | 1 |
| Jacoby, RF | 1 |
| Hohman, C | 1 |
| Marshall, DJ | 1 |
| Frick, TJ | 1 |
| Schlack, S | 1 |
| Broda, M | 1 |
| Smutko, J | 1 |
| Elliott, RW | 1 |
| Rosenberg, DW | 1 |
| Angel, JM | 1 |
| Popova, N | 1 |
| Lanko, N | 1 |
| Turusov, VS | 1 |
| DiGiovanni, J | 1 |
| Kuraguchi, M | 1 |
| Cook, H | 1 |
| Williams, ED | 1 |
| Thomas, GA | 1 |
| Zhang, Z | 1 |
| Li, J | 1 |
| Lantry, LE | 1 |
| Wang, Y | 1 |
| Wiseman, RW | 1 |
| Lubet, RA | 1 |
| You, M | 1 |
| Moen, CJ | 1 |
| van der Valk, MA | 1 |
| Snoek, M | 1 |
| van Zutphen, BF | 1 |
| von Deimling, O | 1 |
| Hart, AA | 1 |
| Demant, P | 1 |
| Deschner, EE | 1 |
| Hakissian, M | 1 |
| Long, FC | 1 |
8 other studies available for 1,2-dimethylhydrazine and Genetic Predisposition
| Article | Year |
|---|---|
Inverse genetic predisposition to colon versus lung carcinogenesis in mouse lines selected based on acute inflammatory responsiveness.
Topics: 1,2-Dimethylhydrazine; Acute Disease; Adenocarcinoma; Adenoma; Animals; Antiviral Agents; Carcinogen | 2006 |
Genetic analysis of colon cancer susceptibility in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Base Sequence; Colonic Neoplasms; Crosses, Genetic; Dimethylhydrazin | 1994 |
Non-homogeneous marking of distal colonic mucosa using Dolichos biflorus lectin.
Topics: 1,2-Dimethylhydrazine; Animals; Binding Sites; Biomarkers, Tumor; Carcinogens; Chimera; Colonic Neop | 1995 |
A locus that influences susceptibility to 1, 2-dimethylhydrazine-induced colon tumors maps to the distal end of mouse chromosome 3.
Topics: 1,2-Dimethylhydrazine; Animals; Chromosome Mapping; Colonic Neoplasms; Crosses, Genetic; Genetic Lin | 2000 |
Differences in susceptibility to colonic stem cell somatic mutation in three strains of mice.
Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Colon; Ethylnitrosourea; Female; Ge | 2001 |
p53 transgenic mice are highly susceptible to 1, 2-dimethylhydrazine-induced uterine sarcomas.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Cell Cycle Pro | 2002 |
The recombinant congenic strains--a novel genetic tool applied to the study of colon tumor development in the mouse.
Topics: 1,2-Dimethylhydrazine; Animals; Biomarkers, Tumor; Carcinogenicity Tests; Colonic Neoplasms; Dimethy | 1991 |
Genetic factors controlling inheritance of susceptibility to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Division; Colonic Neoplasms; Dimethylhydrazines; F | 1989 |