1,2-dimethylhydrazine has been researched along with Folic Acid Deficiency in 3 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ventrella-Lucente, LF | 1 |
Unnikrishnan, A | 1 |
Pilling, AB | 1 |
Patel, HV | 1 |
Kushwaha, D | 1 |
Dombkowski, AA | 1 |
Schmelz, EM | 1 |
Cabelof, DC | 1 |
Heydari, AR | 1 |
Meenan, J | 1 |
Choi, SW | 1 |
Kim, YI | 1 |
Weitzel, JN | 1 |
Mason, JB | 1 |
3 other studies available for 1,2-dimethylhydrazine and Folic Acid Deficiency
Article | Year |
---|---|
Folate deficiency provides protection against colon carcinogenesis in DNA polymerase beta haploinsufficient mice.
Topics: 1,2-Dimethylhydrazine; Animal Feed; Animals; Apoptosis; Colonic Neoplasms; DNA Damage; DNA Polymeras | 2010 |
Co-carcinogenic effect of sulphasalazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cocarcinogenesis; Dimethylhydrazines; Folic Acid Defici | 1993 |
Folate depletion impairs DNA excision repair in the colon of the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colon; DNA Repair; Electrophoresis, Agar Gel; Folic Aci | 1998 |