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1,2-dimethylhydrazine and Ear Neoplasms

1,2-dimethylhydrazine has been researched along with Ear Neoplasms in 6 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Ear Neoplasms: Tumors or cancer of any part of the hearing and equilibrium system of the body (the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR).

Research Excerpts

ExcerptRelevanceReference
"Rats of 3 inbred strains (DA, HS and AS2) were dosed with 1,2-dimethylhydrazine 2HCl (DMH) or saline by gavage weekly for 10 wk."1.26The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine. ( Gavin, JB; Herdson, PB; Teague, CA, 1981)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Teague, CA1
Gavin, JB1
Herdson, PB1
Shetye, J1
Mathiesen, T1
Fagerberg, J1
Rubio, C1
Balansky, R1
Gyosheva, B1
Ganchev, G1
Mircheva, Z1
Minkova, S1
Georgiev, G1
Viñas-Salas, J1
Fortuny, JC1
Panades, J1
Piñol, C1
Prim, M1
Fermiñan, A1
Corbella, G1
Calderó, J1
Egido, R1
Hirose, M2
Masuda, A1
Ito, N2
Kamano, K1
Okuyama, H1
Kurata, Y1
Yamada, M1
Shirai, T1
Ohsawa, T1

Other Studies

6 other studies available for 1,2-dimethylhydrazine and Ear Neoplasms

ArticleYear
The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine.
    Pathology, 1981, Volume: 13, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Dimet

1981
Ear tumours induced by experimental carcinogenesis in the rat: excision prevents early death.
    International journal of colorectal disease, 1994, Volume: 9, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Colore

1994
Inhibitory effects of freeze-dried milk fermented by selected Lactobacillus bulgaricus strains on carcinogenesis induced by 1,2-dimethylhydrazine in rats and by diethylnitrosamine in hamsters.
    Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Biological Therapy; Body Weight; Carcinogen

1999
Appearance of ear tumors in Sprague-Dawley rats treated with 1,2-dimethylhydrazine when used as a model for colonic carcinogenesis.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Carcinoma, Squamous Cell; Colonic Neoplasms; Dimethylhy

1992
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
    Carcinogenesis, 1990, Volume: 11, Issue:5

    Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; alph

1990
Lack of modifying effects of linolic acid hydroperoxides and their secondary oxidative products on combined 7,12-dimethylbenz[a]anthracene and 1,2-dimethylhydrazine-initiated mammary gland, ear duct and colon carcinogenesis in female Sprague-Dawley rats.
    Cancer letters, 1989, Sep-15, Volume: 47, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Colonic Neoplasms; Dimethylhydrazi

1989