1,2-dimethylhydrazine has been researched along with Deficiency, Vitamin E in 3 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this experiment, vitamin E deficiency reduced tumor incidence and calcium supplementation reduced tumor burden, with a significant interaction of the two." | 1.28 | The influence of dietary vitamin E and calcium status on intestinal tumors in rats. ( McIntosh, GH, 1992) |
| "Mean ethane exhalation was highest in animals fed either vitamin E-deficient or high PUFA diets." | 1.27 | In vivo ethane production in vitamin E-deficient rats with DMH-induced colon cancer. ( Aufses, AH; Cohen, G; Kang, J; Slater, G; Szporn, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McIntosh, GH | 1 |
| Slater, G | 1 |
| Kang, J | 1 |
| Cohen, G | 1 |
| Szporn, A | 1 |
| Aufses, AH | 1 |
| Sumiyoshi, H | 1 |
3 other studies available for 1,2-dimethylhydrazine and Deficiency, Vitamin E
| Article | Year |
|---|---|
The influence of dietary vitamin E and calcium status on intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Calcium, Dietary; Dietary Fats; Dimethylhydrazines; Ene | 1992 |
In vivo ethane production in vitamin E-deficient rats with DMH-induced colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Neoplasms; Dimethylhydrazines; Ethane; Fatty Acids, Unsatura | 1987 |
Effects of vitamin E deficiency on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Dimethylhydrazines; Intestinal | 1985 |