1,2-dimethylhydrazine has been researched along with Colonic Diseases in 13 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some human epidemiological studies on colon cancer point to a possible preventive role of dietary fiber, but the results are confounded by the difference in the intake of many other food substances such as fat and the overall differences in the dietary pattern of the populations investigated." | 2.36 | Recent advances in dietary fiber and colorectal diseases. ( Freeman, HJ; Spiller, GA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamiza, OO | 1 |
| Rehman, MU | 1 |
| Khan, R | 1 |
| Tahir, M | 1 |
| Khan, AQ | 1 |
| Lateef, A | 1 |
| Sultana, S | 1 |
| Pandey, S | 1 |
| Singh, A | 1 |
| Kumar, P | 1 |
| Chaudhari, A | 1 |
| Nareshkumar, G | 1 |
| Hsu, CK | 1 |
| Liao, JW | 1 |
| Chung, YC | 1 |
| Hsieh, CP | 1 |
| Chan, YC | 1 |
| Hashimoto, T | 1 |
| Fukunari, A | 1 |
| Yamada, I | 1 |
| Yanaka, N | 1 |
| Chen, D | 1 |
| Kato, N | 1 |
| Toth, B | 1 |
| Spiller, GA | 1 |
| Freeman, HJ | 1 |
| Moen, CJ | 1 |
| van der Valk, MA | 1 |
| Bird, RP | 1 |
| Hart, AA | 1 |
| Demant, P | 1 |
| Ishizuka, S | 1 |
| Kasai, T | 1 |
| Onoue, M | 1 |
| Kado, S | 1 |
| Sakaitani, Y | 1 |
| Uchida, K | 1 |
| Morotomi, M | 1 |
| Chitra, S | 1 |
| Viswanathan, P | 1 |
| Nalini, N | 1 |
| Sabitha, K | 1 |
| Menon, VP | 1 |
| Hambly, RJ | 1 |
| Rumney, CJ | 1 |
| Cunninghame, M | 1 |
| Fletcher, JM | 1 |
| Rijken, PJ | 1 |
| Rowland, IR | 1 |
| Latham, P | 1 |
| Lund, EK | 1 |
| Johnson, IT | 1 |
| Hagiwara, A | 1 |
| Miyashita, K | 1 |
| Nakanishi, T | 1 |
| Sano, M | 1 |
| Tamano, S | 1 |
| Kadota, T | 1 |
| Koda, T | 1 |
| Nakamura, M | 1 |
| Imaida, K | 1 |
| Ito, N | 1 |
| Shirai, T | 1 |
1 review available for 1,2-dimethylhydrazine and Colonic Diseases
| Article | Year |
|---|---|
Recent advances in dietary fiber and colorectal diseases.
Topics: 1,2-Dimethylhydrazine; Animals; Cellulose; Colitis; Colitis, Ulcerative; Colonic Diseases; Colonic N | 1981 |
12 other studies available for 1,2-dimethylhydrazine and Colonic Diseases
| Article | Year |
|---|---|
Chemopreventive effects of aloin against 1,2-dimethylhydrazine-induced preneoplastic lesions in the colon of Wistar rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Colonic Diseases; Emodin; Gene Expression Regulation, | 2014 |
Probiotic Escherichia coli CFR 16 producing pyrroloquinoline quinone (PQQ) ameliorates 1,2-dimethylhydrazine-induced oxidative damage in colon and liver of rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogens; Catalase; Chemical and Drug Induced Liver | 2014 |
Xylooligosaccharides and fructooligosaccharides affect the intestinal microbiota and precancerous colonic lesion development in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Bifidobacterium; Carcinogens; Cecum; Colonic Diseases; Colony Count, | 2004 |
Y-700, a novel inhibitor of xanthine oxidase, suppresses the development of colon aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine-treated mice.
Topics: 1,2-Dimethylhydrazine; Animals; Cell Proliferation; Colon; Colonic Diseases; Dose-Response Relations | 2005 |
Effect of Metamucil on tumour formation by 1,2-dimethylhydrazine dihydrochloride in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Dietary Fiber; Dim | 1984 |
Different genetic susceptibility to aberrant crypts and colon adenomas in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Crosses, | 1996 |
Inhibitory effect of dietary wheat bran on formation of aberrant crypt foci in rat colon induced by a single injection of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Colonic Diseases; Dietary Fiber; Dimethylhydrazines; Intestinal Muco | 1996 |
Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Bacteroides; Bifidobacterium; Carcinogens; Clostridium; Colonic Dise | 1997 |
Role of redchilli (Capsaicin) in the formation of colonic carcinoma.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinoma; Colonic Diseases; Colonic Neoplasms; Dimethylhydrazines; | 1997 |
Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats.
Topics: 1,2-Dimethylhydrazine; Animals; Bacteria; Biomarkers; Body Weight; Colon; Colonic Diseases; Colonic | 1997 |
Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Cell Division; Cell | 1999 |
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Administration, Oral; Anim | 2001 |