1,2-dimethylhydrazine has been researched along with Chronic Disease in 3 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carcinoma was found in both the prolonged reactivation and saline-DMH groups." | 1.34 | Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer. ( Appleyard, CB; Isidro, AA; Pagán, B; Santiago, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nanda, N | 1 |
| Dhawan, DK | 1 |
| Bhatia, A | 1 |
| Mahmood, A | 1 |
| Mahmood, S | 1 |
| Santiago, C | 1 |
| Pagán, B | 1 |
| Isidro, AA | 1 |
| Appleyard, CB | 1 |
| Oliveira, EC | 1 |
| Leite, MS | 1 |
| Miranda, JA | 1 |
| Andrade, AL | 1 |
| Garcia, SB | 1 |
| Luquetti, AO | 1 |
| Moreira, H | 1 |
3 other studies available for 1,2-dimethylhydrazine and Chronic Disease
| Article | Year |
|---|---|
Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Caspase 3; Caspase 9; Cell Proliferatio | 2016 |
Prolonged chronic inflammation progresses to dysplasia in a novel rat model of colitis-associated colon cancer.
Topics: 1,2-Dimethylhydrazine; Adenomatous Polyposis Coli Protein; Animals; Carcinoma; Chronic Disease; Coli | 2007 |
Chronic Trypanosoma cruzi infection associated with low incidence of 1,2-dimethylhydrazine-induced colon cancer in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Chronic Disease; Colonic Neoplasms; Incidence; Male; Ra | 2001 |