1,2-dimethylhydrazine has been researched along with Carcinoma, Colloid in 8 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of intestinal cancer in the control group (dimethylhydrazine only) was 91 percent; in groups provided with inorganic germanium one month before and during dimethylhydrazine treatment, and during dimethylhydrazine treatment only, it was 91 and 78 percent; in groups provided with organic germanium one month before and during dimethylhydrazine treatment, and during dimethylhydrazine treatment only, it was 64 and 64 percent; in groups provided with natural organic germanium one month before and during dimethylhydrazine treatment and during dimethylhydrazine treatment only, it was 50 and 45 percent." | 1.28 | Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats. ( Ho, YS; Jao, SW; Lee, W, 1990) |
| "Colonic cancers were induced in rats by subcutaneous injection of 1,2-Dimethylhydrazine." | 1.28 | [Growth rate of experimental colonic cancer in rats]. ( Shibusawa, M; Takimoto, M; Tsunoda, A, 1990) |
| "Using colonic cancer induced by DMH as experimental model, carcinogenic rate in the rats with or without partial colectomy was compared in order to study the etiology of the local recurrence of large bowel cancer after radical resection and observe the influence of operative injury on carcinogenesis." | 1.27 | [Colonic cancer induced by 1,2-dimethylhydrazine (DMH) in rats after partial colectomy]. ( Wang, CG; Wang, JF; Wang, JP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takemiya, M | 2 |
| Miyayama, H | 2 |
| Takeuchi, T | 2 |
| Hirono, I | 1 |
| Ueno, I | 1 |
| Aiso, S | 1 |
| Yamaji, T | 1 |
| Golberg, L | 1 |
| Hagiwara, A | 1 |
| Miyashita, K | 1 |
| Nakanishi, T | 1 |
| Sano, M | 1 |
| Tamano, S | 1 |
| Kadota, T | 1 |
| Koda, T | 1 |
| Nakamura, M | 1 |
| Imaida, K | 1 |
| Ito, N | 1 |
| Shirai, T | 1 |
| Bandaletova, TIu | 1 |
| Jao, SW | 1 |
| Lee, W | 1 |
| Ho, YS | 1 |
| Tsunoda, A | 1 |
| Shibusawa, M | 1 |
| Takimoto, M | 1 |
| Wang, JP | 1 |
| Wang, JF | 1 |
| Wang, CG | 1 |
8 other studies available for 1,2-dimethylhydrazine and Carcinoma, Colloid
| Article | Year |
|---|---|
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. II. Histochemical and ultrastructural characteristics of glycoproteins of 1,2-dimethylhydrazine-induced carcinoma cells.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Dimethylhydrazines; Glycop | 1982 |
Enhancing effect of dextran sulfate sodium on colorectal carcinogenesis by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Animals; Cocarcinogenesis; | 1983 |
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. I. The induction of mucin producing carcinomas in rat intestine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Cecal Neoplasms; Colonic N | 1982 |
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Administration, Oral; Anim | 2001 |
[Primary localization of 1,2-dimethylhydrazine-induced cancer in lymphoid patches of the large intestine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma, Mucinous; Animals; Colon; Colonic Neoplasms; Dimethylhydrazin | 1990 |
Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Carcinogens; Dimethylhydra | 1990 |
[Growth rate of experimental colonic cancer in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Barium Sulfate; Colonic Ne | 1990 |
[Colonic cancer induced by 1,2-dimethylhydrazine (DMH) in rats after partial colectomy].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Colectomy; Colonic Neoplas | 1987 |