1,2-dimethylhydrazine has been researched along with Carcinogenesis in 60 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis." | 8.12 | Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022) |
| "This study aimed to evaluate the cancer chemopreventive activity of vanillic acid (VA) in diethylnitrosamine- and 1,2-dimethylhydrazine-induced liver and colon carcinogenesis in rats." | 8.02 | Protective Role of Vanillic Acid against Diethylnitrosamine- and 1,2-Dimethylhydrazine-Induced Hepatocarcinogenesis in Rats. ( Chariyakornkul, A; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R, 2021) |
| "Capsaicin (CPS, 8-methyl-N-vanillyl-trans-6-nonenamide), a pungent alkaloid from chili peppers, has contradictory effects in both experimental and human carcinogenesis." | 8.02 | Capsaicin lacks tumor-promoting effects during colon carcinogenesis in a rat model induced by 1,2-dimethylhydrazine. ( Barbisan, LF; Caetano, BFR; de Moura, NA; Ignoti, MG; Rodrigues, MAM; Romualdo, GR; Tablas, MB, 2021) |
| "2 mol% PlsEtn in EtnGpl) in 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in vivo, and elucidated the possible underlying mechanisms behind it." | 8.02 | Dietary PlsEtn Ameliorates Colon Mucosa Inflammatory Stress and ACF in DMH-Induced Colon Carcinogenesis Mice: Protective Role of Vinyl Ether Linkage. ( Kinoshita, M; Miyazawa, T; Nakagawa, K; Nguma, E; Otoki, Y; Tominaga, Y; Yamamoto, A; Yamashita, S, 2021) |
| " This study was designed to evaluate the effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis in rats." | 7.96 | Effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis. ( Ji, X; Liang, H; Liu, Y; Sun, T; Xue, M; Zhang, L; Zhou, Z, 2020) |
| " BALB/c mice (n = 5/group) were administered the pro-carcinogen 1,2-dimethylhydrazine (DMH) for 8 weeks (20 mg/kg body weight/week) to induce colon carcinogenesis, and then exposed for 4 weeks to two physical stressors: restraint and forced-swimming." | 7.96 | Chronic stress decreases ornithine decarboxylase expression and protects against 1,2-dimethylhydrazine-induced colon carcinogenesis. ( Casas-Solís, J; Castro-Félix, P; Huizar-López, MDR; Marques-González, MLBI; Martin Del Campo-Solís, MF; Santerre, A; Zamora-González, EO, 2020) |
| "Diethylnitrosamine (DEN) and 1,2-dimethylhydrazine (DMH) are classical carcinogens used in experimental rodent carcinogenesis." | 7.91 | Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine. ( Chariyakornkul, A; Chewonarin, T; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R, 2019) |
| "This study was designated to explore the role of cancer stem cells (CSCs) during chemically induced mouse colon carcinogenesis (by 1,2- dimethylhydrazine dihydrochloride, DMH) with/or without the treatment with a targeted (anti-COX-2) therapeutic drug, celecoxib." | 7.91 | Celecoxib Targeted Therapy Attenuates Mouse Colon Carcinogenesis through Modulation of Expression Patterns of Cancer Stem Cells. ( Eltonouby, EA; Hegazi, MM; Helmy, HM; Kang, JS; Mahfouz, ME; Salim, EI, 2019) |
| "Colorectal cancer has been found to be attenuated either with prophylactic manipulation of gut microbiome with probiotics or celecoxib, a non-steroidal anti-inflammatory drug mainly by suppressing early pro-carcinogenic markers in various experimental studies." | 7.88 | Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis. ( Chandel, D; Sharaf, LK; Sharma, M; Shukla, G, 2018) |
| " The aim of this study was to investigate the ability of RA to prevent 1,2-dimethylhydrazine (DMH)-induced primary DNA damage and aberrant crypt foci (ACF) in Wistar rat colon." | 7.81 | Chemopreventive effects of rosmarinic acid on rat colon carcinogenesis. ( Cleto, SS; Cunha, WR; Furtado, RA; Munari, CC; Oliveira, BR; Silva, LR; Tavares, DC, 2015) |
| " The present study was carried out to divulge the protective potential of the probiotic Dahi containing Lactobacillus acidophilus LaVK2 and Bifidobacterium bifidum BbVK3 alone or in combination with piroxicam (PXC) on the development of early biomarkers of colorectal carcinogenesis in male Wistar rats administered 1,2-dimethylhydrazine (DMH)." | 7.80 | Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats. ( Kansal, VK; Kruzliak, P; Kumari, A; Mohania, D, 2014) |
| " In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)." | 7.80 | Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014) |
| "This study was conducted to investigate the role of curcumin and zinc on the biokinetics and biodistribution of (65)Zn during colon carcinogenesis." | 7.80 | Regulation of biokinetics of (65)Zn by curcumin and zinc in experimentally induced colon carcinogenesis in rats. ( Dhawan, DK; Jain, K, 2014) |
| "The present study has aimed to evaluate chemopreventive potential of d-carvone on oxidative stress markers, biotransforming enzymes, incidence of colonic polyps and aberrant crypt foci (ACF) in 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis." | 7.79 | Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis. ( Balasubramanian, T; Kabalimoorthy, J; Nalini, N; Sudha, M; Vinothkumar, R; Viswanathan, P, 2013) |
| "This study investigated the effect of short curcumin treatment, a natural antioxidant on 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in mice." | 7.78 | Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-β1 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice. ( Bounaama, A; Djerdjouri, B; Laroche-Clary, A; Le Morvan, V; Robert, J, 2012) |
| "Diacerein (DIA) is an anti-inflammatory used for treatment of osteoarthritis." | 5.72 | Effect of Diacerein on HOTAIR/IL-6/STAT3, Wnt/β-Catenin and TLR-4/NF-κB/TNF-α axes in colon carcinogenesis. ( Alnasser, DM; Altemani, R; Ebrahim, HA; Eisa, NH; El-Sherbiny, M; Elsherbini, DMA; Elsherbiny, NM; Khodir, AE; Sabry, D; Said, E, 2022) |
| "Background Colorectal cancer (CRC) is a major public health problem, with almost 1." | 5.56 | Protective effect of Matricaria chamomilla extract against 1,2-dimethylhydrazine-induced colorectal cancer in mice. ( Borjac, JM; El Joumaa, MM; Rizk, S; Taleb, RI, 2020) |
| "Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA." | 5.51 | Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019) |
| "Colon cancer is thought to develop in a stepwise fashion." | 5.48 | Precancerous ACF induction affects their regional distribution forsaking oxidative stress implication in 1,2-dimethylhydrazine-induced colon carcinogenesis model. ( Clichici, S; Djerdjouri, B; Moulahoum, H; Nagy, AL, 2018) |
| "Colon carcinogenesis is long known to be associated with ulcerative colitis (UC), a chronic gastrointestinal disorder." | 5.43 | Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis. ( Jena, GB; Kumar, V; Tikoo, KB; Trivedi, PP, 2016) |
| "Initiation and induction of colon carcinogenesis were achieved through weekly subcutaneous injections of DMH (30 mg/kg body weight) for both 10 and 20 weeks." | 5.42 | Chemopreventive Effects of Azadirachta indica on Cancer Marker Indices and Ultrastructural Changes During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats. ( Liu, N; Sun, B; Wei, X; Wu, P, 2015) |
| " Therefore, the authors studied whether long-term administration of the DPP4i Sitagliptin (SITA) affects 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis." | 5.39 | Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats. ( Caderni, G; Femia, AP; Lodovici, M; Maglieri, G; Mannucci, E; Raimondi, L, 2013) |
| "For this purpose, colon cancer was induced by DMH in rats (20 mg/kg body weight for 5 weeks) and groups of animals were given dietary caraway essential oils at two levels (0." | 5.39 | Effect of dietary caraway essential oils on expression of β-catenin during 1,2-dimethylhydrazine-induced colonic carcinogenesis. ( Allameh, A; Ashrafi-Helan, J; Dadkhah, A; Fatemi, F; Rahbarizadeh, F, 2013) |
| " The present study aimed to determine the preventive action of Ficus dubia latex extract (FDLE) on 1,2-dimethylhydrazine (DMH)-induced rat colorectal carcinogenesis and its mechanisms." | 4.12 | Ficus dubia latex extract prevent DMH-induced rat early colorectal carcinogenesis through the regulation of xenobiotic metabolism, inflammation, cell proliferation and apoptosis. ( Chantana, W; Chantarasuwan, B; Chewonarin, T; Hu, R; Pitchakarn, P; Subhawa, S; Temviriyanukul, P, 2022) |
| " Thus, it was assessed whether caffeine (CAF) and/or chlorogenic acid (CGA) attenuates the early-stage of chemically induced mouse colon carcinogenesis." | 4.12 | Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p. ( Barbisan, LF; Bartolomeu, AR; Besharat, ZM; Chaves, MÁG; Corrales, JAM; Lisón, CG; Romualdo, GR, 2022) |
| "2 mol% PlsEtn in EtnGpl) in 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in vivo, and elucidated the possible underlying mechanisms behind it." | 4.02 | Dietary PlsEtn Ameliorates Colon Mucosa Inflammatory Stress and ACF in DMH-Induced Colon Carcinogenesis Mice: Protective Role of Vinyl Ether Linkage. ( Kinoshita, M; Miyazawa, T; Nakagawa, K; Nguma, E; Otoki, Y; Tominaga, Y; Yamamoto, A; Yamashita, S, 2021) |
| "This study aimed to evaluate the cancer chemopreventive activity of vanillic acid (VA) in diethylnitrosamine- and 1,2-dimethylhydrazine-induced liver and colon carcinogenesis in rats." | 4.02 | Protective Role of Vanillic Acid against Diethylnitrosamine- and 1,2-Dimethylhydrazine-Induced Hepatocarcinogenesis in Rats. ( Chariyakornkul, A; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R, 2021) |
| "To simulate carcinogenesis, 1,2-dimethylhydrazine (DMH) was administered subcutaneously to 76 rats for 30 weeks at a dose of 7." | 3.96 | State of humoral immunity and cytokine profile in rats under experimental carcinogenesis with applying enterosorporation chemotherapeutic factors. ( Fira, D; Fira, L; Kachur, O; Kramar, S; Lykhatskyi, P, 2020) |
| " BALB/c mice (n = 5/group) were administered the pro-carcinogen 1,2-dimethylhydrazine (DMH) for 8 weeks (20 mg/kg body weight/week) to induce colon carcinogenesis, and then exposed for 4 weeks to two physical stressors: restraint and forced-swimming." | 3.96 | Chronic stress decreases ornithine decarboxylase expression and protects against 1,2-dimethylhydrazine-induced colon carcinogenesis. ( Casas-Solís, J; Castro-Félix, P; Huizar-López, MDR; Marques-González, MLBI; Martin Del Campo-Solís, MF; Santerre, A; Zamora-González, EO, 2020) |
| " This study was designed to evaluate the effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis in rats." | 3.96 | Effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis. ( Ji, X; Liang, H; Liu, Y; Sun, T; Xue, M; Zhang, L; Zhou, Z, 2020) |
| "To investigate how intestinal bacteria affect host cytogenetic alterations in the early initiation step of colon carcinogenesis, we conducted a comet assay and micronucleus (MN) test using germ-free (GF) and conventionalized (Cvd) rats after a single subcutaneous injection of the carcinogen, 1,2-dimethylhydrazine dihydrochloride (DMH)." | 3.91 | Markedly enhanced micronucleus induction by 1,2-dimethylhydrazine dihydrochloride in colonic cells of rats with bacterial colonization in the intestine. ( Ohyama, W, 2019) |
| "Diethylnitrosamine (DEN) and 1,2-dimethylhydrazine (DMH) are classical carcinogens used in experimental rodent carcinogenesis." | 3.91 | Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine. ( Chariyakornkul, A; Chewonarin, T; Jarukamjorn, K; Punvittayagul, C; Wongpoomchai, R, 2019) |
| "This study was designated to explore the role of cancer stem cells (CSCs) during chemically induced mouse colon carcinogenesis (by 1,2- dimethylhydrazine dihydrochloride, DMH) with/or without the treatment with a targeted (anti-COX-2) therapeutic drug, celecoxib." | 3.91 | Celecoxib Targeted Therapy Attenuates Mouse Colon Carcinogenesis through Modulation of Expression Patterns of Cancer Stem Cells. ( Eltonouby, EA; Hegazi, MM; Helmy, HM; Kang, JS; Mahfouz, ME; Salim, EI, 2019) |
| "Colorectal cancer has been found to be attenuated either with prophylactic manipulation of gut microbiome with probiotics or celecoxib, a non-steroidal anti-inflammatory drug mainly by suppressing early pro-carcinogenic markers in various experimental studies." | 3.88 | Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis. ( Chandel, D; Sharaf, LK; Sharma, M; Shukla, G, 2018) |
| " Glycyrrhizic acid (GA) is an active constituent of licorice with anti-inflammatory and anticarcinogenesis effects." | 3.88 | Glycyrrhizic acid suppresses 1,2-dimethylhydrazine-induced colon tumorigenesis in Wistar rats: Alleviation of inflammatory, proliferation, angiogenic, and apoptotic markers. ( Khan, AQ; Khan, R; Rehman, MU; Sultana, S; Tahir, M, 2018) |
| " The aim of this study was to investigate the ability of RA to prevent 1,2-dimethylhydrazine (DMH)-induced primary DNA damage and aberrant crypt foci (ACF) in Wistar rat colon." | 3.81 | Chemopreventive effects of rosmarinic acid on rat colon carcinogenesis. ( Cleto, SS; Cunha, WR; Furtado, RA; Munari, CC; Oliveira, BR; Silva, LR; Tavares, DC, 2015) |
| " C-phycocyanin, a biliprotein from Spirulina platensis and a selective COX-2 inhibitor along with piroxicam, a traditional nonsteroidal antiinflammatory drug was used to investigate the role of cell cycle regulatory proteins and proinflammatory transcription factor NFκB in 1,2-dimethylhydrazine dihydrochloride (DMH)-induced rat colon carcinogenesis." | 3.81 | Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors. ( Saini, MK; Sanyal, SN, 2015) |
| "This study was aimed to investigate the effect of sinapic acid (SA) on 1,2-dimethylhydrazine (DMH) induced experimental rat colon carcinogenesis." | 3.81 | Effect of sinapic acid on 1,2 dimethylhydrazine induced aberrant crypt foci, biotransforming bacterial enzymes and circulatory oxidative stress status in experimental rat colon carcinogenesis. ( Balaji, C; Muthukumaran, J; Nalini, N, 2015) |
| "This work investigated the effects of Vitamin E (VE) on aberrant crypt foci (ACF) incidence, oxidative stress parameters (serum and hepatic VE concentration, and homocysteine, glutathione (GSH), and malondialdehyde (MDA) levels), and expression of both cyclooxygenase-2 (COX2) and proliferating cellular nuclear antigen (PCNA) in experimental colorectal carcinogenesis." | 3.80 | Vitamin E supplementation in chemical colorectal carcinogenesis: a two-edged knife. ( Cardoso, JF; Cohen, C; Garcia, SB; Vannucchi, H, 2014) |
| " The present study was carried out to divulge the protective potential of the probiotic Dahi containing Lactobacillus acidophilus LaVK2 and Bifidobacterium bifidum BbVK3 alone or in combination with piroxicam (PXC) on the development of early biomarkers of colorectal carcinogenesis in male Wistar rats administered 1,2-dimethylhydrazine (DMH)." | 3.80 | Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats. ( Kansal, VK; Kruzliak, P; Kumari, A; Mohania, D, 2014) |
| " In our study, we have evaluated the effect of different doses of zingerone on lipid peroxidation (thiobarbituric acid-reactive substances, lipid hydroxyl radical and conjugated dienes), tissue enzymatic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), and nonenzymatic antioxidants (reduced glutathione, vitamin E, vitamin C), and also the formation of aberrant crypt foci (ACF) in male albino Wistar rats with colon cancer induced using 1,2-dimethylhydrazine (DMH)." | 3.80 | Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats. ( Nalini, N; Sudha, M; Vinothkumar, R, 2014) |
| "This study was conducted to investigate the role of curcumin and zinc on the biokinetics and biodistribution of (65)Zn during colon carcinogenesis." | 3.80 | Regulation of biokinetics of (65)Zn by curcumin and zinc in experimentally induced colon carcinogenesis in rats. ( Dhawan, DK; Jain, K, 2014) |
| "This study investigated the protective effect of spray-dried açaí powder (AP) intake on colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH) in male Wistar rats." | 3.79 | Açai (Euterpe oleracea Mart.) feeding attenuates dimethylhydrazine-induced rat colon carcinogenesis. ( Barbisan, LF; Fragoso, MF; Ribeiro, DA; Romualdo, GR, 2013) |
| "The present study has aimed to evaluate chemopreventive potential of d-carvone on oxidative stress markers, biotransforming enzymes, incidence of colonic polyps and aberrant crypt foci (ACF) in 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis." | 3.79 | Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis. ( Balasubramanian, T; Kabalimoorthy, J; Nalini, N; Sudha, M; Vinothkumar, R; Viswanathan, P, 2013) |
| "This study investigated the effect of short curcumin treatment, a natural antioxidant on 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in mice." | 3.78 | Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-β1 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice. ( Bounaama, A; Djerdjouri, B; Laroche-Clary, A; Le Morvan, V; Robert, J, 2012) |
| "Diacerein (DIA) is an anti-inflammatory used for treatment of osteoarthritis." | 1.72 | Effect of Diacerein on HOTAIR/IL-6/STAT3, Wnt/β-Catenin and TLR-4/NF-κB/TNF-α axes in colon carcinogenesis. ( Alnasser, DM; Altemani, R; Ebrahim, HA; Eisa, NH; El-Sherbiny, M; Elsherbini, DMA; Elsherbiny, NM; Khodir, AE; Sabry, D; Said, E, 2022) |
| "For this, mice induced to carcinogenesis were fed with standard diet AIN-93 M (CON), diet AIN-93 M and VSL#3 (PRO) or diet AIN-93 M with yacon and VSL#3 (SYN)." | 1.72 | Synbiotic modulates intestinal microbiota metabolic pathways and inhibits DMH-induced colon tumorigenesis through c-myc and PCNA suppression. ( da Silva Duarte, V; de Luces Fortes Ferreira, CL; de Paula, SO; do Carmo Gouveia Peluzio, M; Dos Santos Cruz, BC; Ladeira Bernardes, A; Sousa Dias, R, 2022) |
| "After simulation of colon cancer, the animals were intragastricly administered entorosorbent at a dose of 1 ml of suspension (corresponding to 0." | 1.72 | Evaluation of membrane-destructive processes in rats with induced carcinogenesis of the colon using the cytostatic vincristine. ( Fira, D; Fira, L; Garlitska, N; Kachur, O; Lykhatskyі, P, 2022) |
| "DMH-induced carcinogenesis is associated with enzymatic/non-enzymatic redox imbalance as well as increased oxidative damage to proteins and lipids." | 1.56 | [VIOLATION OF THE PROOXIDANT-ANTIOXIDANT BALANCE IN THE SPLEEN TISSUE UNDER EXPERIMENTAL CARCINOGENESIS]. ( Andriichuk, I; Fira, L; Lisnychuk, N; Lykhatskyi, P; Soroka, Y, 2020) |
| "Background Colorectal cancer (CRC) is a major public health problem, with almost 1." | 1.56 | Protective effect of Matricaria chamomilla extract against 1,2-dimethylhydrazine-induced colorectal cancer in mice. ( Borjac, JM; El Joumaa, MM; Rizk, S; Taleb, RI, 2020) |
| "Treatment with zingerone to DMH treated rats, resulted in alterations in the activity of the cytochrome P450 2E1 and CEA." | 1.51 | Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats. ( Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K, 2019) |
| "Colon cancer is thought to develop in a stepwise fashion." | 1.48 | Precancerous ACF induction affects their regional distribution forsaking oxidative stress implication in 1,2-dimethylhydrazine-induced colon carcinogenesis model. ( Clichici, S; Djerdjouri, B; Moulahoum, H; Nagy, AL, 2018) |
| "the third pathway of colonic carcinogenesis, remain unidentified." | 1.46 | The Histogenesis of the Third Pathway of Colonic Carcinogenesis in Rats. ( Rubio, CA, 2017) |
| "CICC was induced with the colon cancer agent 1,2 dimethyl hydrazine (DMH) along with dextran sodium sulfate (DSS)." | 1.46 | Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. ( Carson, JA; Chanda, A; Fayad, R; Greer, J; Kaur, K; Saxena, A; Truman, S, 2017) |
| "Colon carcinogenesis is long known to be associated with ulcerative colitis (UC), a chronic gastrointestinal disorder." | 1.43 | Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis. ( Jena, GB; Kumar, V; Tikoo, KB; Trivedi, PP, 2016) |
| "Colorectal cancer is a very prevalent diagnosed cancer." | 1.43 | Anti-proliferative and Apoptotic Effects of Basella rubra (L.) Against 1, 2-Dimethyl Hydrazine-induced Colon Carcinogenesis in Rats. ( Kilari, BP; Kotakadi, VS; Penchalaneni, J, 2016) |
| "Initiation and induction of colon carcinogenesis were achieved through weekly subcutaneous injections of DMH (30 mg/kg body weight) for both 10 and 20 weeks." | 1.42 | Chemopreventive Effects of Azadirachta indica on Cancer Marker Indices and Ultrastructural Changes During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats. ( Liu, N; Sun, B; Wei, X; Wu, P, 2015) |
| " Therefore, the authors studied whether long-term administration of the DPP4i Sitagliptin (SITA) affects 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis." | 1.39 | Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats. ( Caderni, G; Femia, AP; Lodovici, M; Maglieri, G; Mannucci, E; Raimondi, L, 2013) |
| "For this purpose, colon cancer was induced by DMH in rats (20 mg/kg body weight for 5 weeks) and groups of animals were given dietary caraway essential oils at two levels (0." | 1.39 | Effect of dietary caraway essential oils on expression of β-catenin during 1,2-dimethylhydrazine-induced colonic carcinogenesis. ( Allameh, A; Ashrafi-Helan, J; Dadkhah, A; Fatemi, F; Rahbarizadeh, F, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 37 (61.67) | 24.3611 |
| 2020's | 23 (38.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sadighparvar, S | 1 |
| Darband, SG | 1 |
| Ghaderi-Pakdel, F | 1 |
| Mihanfar, A | 1 |
| Majidinia, M | 1 |
| Fedoros, EI | 1 |
| Tyndyk, ML | 1 |
| Popovich, IG | 1 |
| Anikin, IV | 1 |
| Yurova, MN | 1 |
| Gubareva, EA | 1 |
| Pigarev, SE | 1 |
| Panchenko, AV | 1 |
| Solovyev, ND | 1 |
| Anisimov, VN | 1 |
| Bartolomeu, AR | 1 |
| Romualdo, GR | 4 |
| Lisón, CG | 1 |
| Besharat, ZM | 1 |
| Corrales, JAM | 1 |
| Chaves, MÁG | 1 |
| Barbisan, LF | 4 |
| Kachur, O | 2 |
| Fira, L | 3 |
| Lykhatskyі, P | 1 |
| Fira, D | 2 |
| Garlitska, N | 1 |
| Dos Santos Cruz, BC | 1 |
| da Silva Duarte, V | 1 |
| Sousa Dias, R | 1 |
| Ladeira Bernardes, A | 1 |
| de Paula, SO | 1 |
| de Luces Fortes Ferreira, CL | 1 |
| do Carmo Gouveia Peluzio, M | 1 |
| Eisa, NH | 1 |
| Said, E | 1 |
| Khodir, AE | 1 |
| Sabry, D | 1 |
| Ebrahim, HA | 1 |
| Elsherbini, DMA | 1 |
| Altemani, R | 1 |
| Alnasser, DM | 1 |
| Elsherbiny, NM | 1 |
| El-Sherbiny, M | 1 |
| Hu, R | 1 |
| Chantana, W | 1 |
| Pitchakarn, P | 1 |
| Subhawa, S | 1 |
| Chantarasuwan, B | 1 |
| Temviriyanukul, P | 1 |
| Chewonarin, T | 2 |
| de Oliveira, CS | 1 |
| Baptistella, MM | 1 |
| Siqueira, AP | 1 |
| Carvalho, MO | 1 |
| Ramos, LF | 1 |
| Souto, BS | 1 |
| de Almeida, LA | 1 |
| Dos Santos, EG | 1 |
| Novaes, RD | 1 |
| Nogueira, ESC | 1 |
| de Oliveira, PF | 1 |
| Vachiraarunwong, A | 1 |
| Tuntiwechapikul, W | 1 |
| Wongnoppavich, A | 1 |
| Meepowpan, P | 1 |
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60 other studies available for 1,2-dimethylhydrazine and Carcinogenesis
| Article | Year |
|---|---|
Parasympathetic, but not sympathetic denervation, suppressed colorectal cancer progression.
Topics: 1,2-Dimethylhydrazine; Animals; Atropine; Carcinogenesis; Carcinogens; Colon; Colorectal Neoplasms; | 2021 |
Assessment of antitumor activity of BP-C1, a platinum-based anticancer agent with a lignin-derived polymeric ligand, in autochthonous induced and spontaneous carcinogenesis rodent models.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzo(a)py | 2022 |
Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p.
Topics: 1,2-Dimethylhydrazine; Animals; Caffeine; Carcinogenesis; Chlorogenic Acid; Coffee; Colon; Colonic N | 2022 |
Evaluation of membrane-destructive processes in rats with induced carcinogenesis of the colon using the cytostatic vincristine.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Carcinogens; Colonic Neoplasms; Cytosta | 2022 |
Synbiotic modulates intestinal microbiota metabolic pathways and inhibits DMH-induced colon tumorigenesis through c-myc and PCNA suppression.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Colorectal Neoplasms; Gastrointestinal Microbiome; M | 2022 |
Effect of Diacerein on HOTAIR/IL-6/STAT3, Wnt/β-Catenin and TLR-4/NF-κB/TNF-α axes in colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Annexin A5; Anthraquinones; Anti-Inflammatory Agents; Anticarcinogenic Agents | 2022 |
Ficus dubia latex extract prevent DMH-induced rat early colorectal carcinogenesis through the regulation of xenobiotic metabolism, inflammation, cell proliferation and apoptosis.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Di | 2022 |
Combination of vitamin D and probiotics inhibits chemically induced colorectal carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Colonic Neoplasms; Colorectal Neoplasms; Probiotics; | 2023 |
2,4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone from Cleistocalyx nervosum var. paniala seeds attenuated the early stage of diethylnitrosamine and 1,2-dimethylhydrazine-induced colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Colorectal Neoplasms; Diethylnitrosamine; Humans; Ra | 2023 |
Panx1 knockout promotes preneoplastic aberrant crypt foci development in a chemically induced model of mouse colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Carcinogenesis; Colon; Colonic Neoplasms; Conne | 2023 |
Synergistic Antigenotoxic and Antioxidant Action of Gum Arabic and Eugenol in Rat Liver Following Induction of Colorectal Carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogenesis; Colonic Neoplasms; Eugenol; Gum Arabic | 2023 |
NANOPARTICLES AND COLORECTAL CANCER: CAN THE USE OF METAL NANOPARTICLE COMPOSITIONS AFFECT OXIDATIVE STRESS MARKERS AND COLON HISTOLOGICAL CHANGES UNDER DMH-INDUCED CARCINOGENESIS.
Topics: 1,2-Dimethylhydrazine; Carcinogenesis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Humans; Metal | 2023 |
Juçara (
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Carcinogenesis; Colorectal Neoplasms; Dietary S | 2020 |
Evaluation of immunologic and intestinal effects in rats administered an E 171-containing diet, a food grade titanium dioxide (TiO
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; CD4-Positive T-Lymphocytes; Cytokines; | 2019 |
Consumption of Low-Dose of Ethanol Suppresses Colon Tumorigenesis in 1,2-Dimethylhydrazine-Treated Rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogenesis; Colon; Coloni | 2019 |
Protective effect of Matricaria chamomilla extract against 1,2-dimethylhydrazine-induced colorectal cancer in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Chamomile; Colon; Colonic Polyps; Colorectal Neoplas | 2020 |
Effects of fucoidan on gut flora and tumor prevention in 1,2-dimethylhydrazine-induced colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Apoptosis; Bacteroidetes; Carcinogenesis; Col | 2020 |
Celecoxib Targeted Therapy Attenuates Mouse Colon Carcinogenesis through Modulation of Expression Patterns of Cancer Stem Cells.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Celecoxib; Colonic Neoplasms; Cyclooxyg | 2019 |
Capsaicin lacks tumor-promoting effects during colon carcinogenesis in a rat model induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Capsaicin; Carcinogenesis; Carcinogens; Rats; Rats, Wistar | 2021 |
Methanolic Extract of
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogenesis; Colon; Colonic Neoplasms; Methanol; Pl | 2021 |
Dietary PlsEtn Ameliorates Colon Mucosa Inflammatory Stress and ACF in DMH-Induced Colon Carcinogenesis Mice: Protective Role of Vinyl Ether Linkage.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Apoptosis; Carcinogenesis; Colon; Dietary Expos | 2021 |
Chronic stress decreases ornithine decarboxylase expression and protects against 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Colon; Colonic Neoplasms; Corticosteron | 2020 |
State of humoral immunity and cytokine profile in rats under experimental carcinogenesis with applying enterosorporation chemotherapeutic factors.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Colon; Colonic Neoplasms; Cytokines; Humans; Immunit | 2020 |
[VIOLATION OF THE PROOXIDANT-ANTIOXIDANT BALANCE IN THE SPLEEN TISSUE UNDER EXPERIMENTAL CARCINOGENESIS].
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogenesis; Catalase; Glutathione Peroxidase; Lipi | 2020 |
Protective Role of Vanillic Acid against Diethylnitrosamine- and 1,2-Dimethylhydrazine-Induced Hepatocarcinogenesis in Rats.
Topics: 1,2-Dimethylhydrazine; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Carcin | 2021 |
Effect of cold exposure and capsaicin on the expression of histone acetylation and Toll-like receptors in 1,2-dimethylhydrazine-induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Acetylation; Animals; Capsaicin; Carcinogenesis; Colon; Colonic Neoplasms; Hi | 2021 |
The Histogenesis of the Third Pathway of Colonic Carcinogenesis in Rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Carcinogenesis; Carcinoma; Carcinoma, Signet Ring Cell; Cel | 2017 |
Precancerous ACF induction affects their regional distribution forsaking oxidative stress implication in 1,2-dimethylhydrazine-induced colon carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Antioxidants; Biomarkers, Tumor; Carcinogenesis | 2018 |
Protective effect of p-coumaric acid against 1,2 dimethylhydrazine induced colonic preneoplastic lesions in experimental rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcin | 2017 |
Orientin, a C-glycosyl dietary flavone, suppresses colonic cell proliferation and mitigates NF-κB mediated inflammatory response in 1,2-dimethylhydrazine induced colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Biomarkers, Tumor; | 2017 |
Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Colon; Diethylnitro | 2019 |
Anti-inflammatory and anticancer effects of p-methoxycinnamic acid, an active phenylpropanoid, against 1,2-dimethylhydrazine-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Apopto | 2019 |
Glycyrrhizic acid suppresses 1,2-dimethylhydrazine-induced colon tumorigenesis in Wistar rats: Alleviation of inflammatory, proliferation, angiogenic, and apoptotic markers.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Apoptosis; Biomarkers; Carcinogenesis; Cell | 2018 |
Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced experimental colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Carcinogens; | 2018 |
Markedly enhanced micronucleus induction by 1,2-dimethylhydrazine dihydrochloride in colonic cells of rats with bacterial colonization in the intestine.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Proliferation; Colon; C | 2019 |
Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Coloni | 2019 |
Açai (Euterpe oleracea Mart.) feeding attenuates dimethylhydrazine-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Arecaceae; beta Catenin; Carcinogenesis; Carcinogens; Cel | 2013 |
Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Colonic Neoplasms; Dipeptidyl Peptidase | 2013 |
Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Carcinog | 2014 |
Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Body Weight; Carcinogenesis; Chemoprevention; C | 2013 |
Modulation of expression of Programmed Death-1 by administration of probiotic Dahi in DMH-induced colorectal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Dimenhydrinate; Probiotics; Rats; Rats, | 2013 |
Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Bifidobacterium; Body Weight; Buffaloes; Carcin | 2014 |
Lactobacillus salivarius Ren prevent the early colorectal carcinogenesis in 1, 2-dimethylhydrazine-induced rat model.
Topics: 1,2-Dimethylhydrazine; Animals; Antibiosis; Bacillus; Body Weight; Carcinogenesis; Cell Proliferatio | 2014 |
Chemopreventive effects of rosmarinic acid on rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Adenocarcinoma; Animals; Antioxidants; Carcinogenesis; C | 2015 |
Synbiotic (Lactobacillus rhamnosus+Lactobacillus acidophilus+inulin) attenuates oxidative stress and colonic damage in 1,2 dimethylhydrazine dihydrochloride-induced colon carcinogenesis in Sprague-Dawley rats: a long-term study.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Colon; Colonic Neoplasms; Inulin; Lacti | 2014 |
Vitamin E supplementation in chemical colorectal carcinogenesis: a two-edged knife.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Biomarkers; Carcinogenesis; Carcinogens; Cell P | 2014 |
Regulation of biokinetics of (65)Zn by curcumin and zinc in experimentally induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogenesis; Carcinogens; Colonic Neoplasms; Curcumin; Male; Rats | 2014 |
Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis-associated colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Autophagy; Carcinogenesis; Carcinogens; Col | 2016 |
Chemopreventive Effects of Azadirachta indica on Cancer Marker Indices and Ultrastructural Changes During 1,2-Dimethylhydrazine-Induced Colon Carcinogenesis in Rats.
Topics: 1,2-Dimethylhydrazine; Alkaline Phosphatase; Animals; Antineoplastic Agents; Azadirachta; Biomarkers | 2015 |
[Morphological and immunohistochemical characteristics of the thymus during chemical carcinogenesis induced by 1,2-dimethylhydrazine administration].
Topics: 1,2-Dimethylhydrazine; Animals; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Colonic Neoplasms; M | 2014 |
Cell cycle regulation and apoptotic cell death in experimental colon carcinogenesis: intervening with cyclooxygenase-2 inhibitors.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apop | 2015 |
Probiotics Clostridium butyricum and Bacillus subtilis ameliorate intestinal tumorigenesis.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Apoptosis; Bacillus subtilis; Carcinogenesis; | 2015 |
Effect of sinapic acid on 1,2 dimethylhydrazine induced aberrant crypt foci, biotransforming bacterial enzymes and circulatory oxidative stress status in experimental rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anti-Infective Agents; Carcinogenesis; Catalase | 2015 |
Anti-proliferative and Apoptotic Effects of Basella rubra (L.) Against 1, 2-Dimethyl Hydrazine-induced Colon Carcinogenesis in Rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Antigens, Nuclear; Apoptosis; Biomarkers, Tumor | 2016 |
Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Caspase 3; Caspase 9; Cell Proliferatio | 2016 |
Evolutionary biologic changes of gut microbiota in an 'adenoma-carcinoma sequence' mouse colorectal cancer model induced by 1, 2-Dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Adenomatous Polyposis Coli Protein; Animals; Bacteri | 2017 |
Morin and Esculetin supplementation modulates c-myc induced energy metabolism and attenuates neoplastic changes in rats challenged with the procarcinogen 1,2 - dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Body Weight; Carcinogenesis; | 2017 |
Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer.
Topics: 1,2-Dimethylhydrazine; Adiponectin; Animals; Basic Helix-Loop-Helix Transcription Factors; Carcinoge | 2017 |
Effect of dietary caraway essential oils on expression of β-catenin during 1,2-dimethylhydrazine-induced colonic carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; beta Catenin; Carcinog | 2013 |
Short curcumin treatment modulates oxidative stress, arginase activity, aberrant crypt foci, and TGF-β1 and HES-1 transcripts in 1,2-dimethylhydrazine-colon carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Antioxidants; Apoptosis; Arginase; Basic Helix- | 2012 |