1,2-dimethylhydrazine has been researched along with Cancer of Intestines in 80 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| " weekly after the 1st 2 drug doses, the dosage as base being 9." | 5.29 | Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats. ( Gershbein, LL, 1993) |
| " Intestinal tumors were induced by 1,2-dimethylhydrazine (DMH) given subcutaneously as 16 weekly doses at 20 mg/kg body weight." | 3.71 | Effects of high molybdenum intake on 1,2-dimethylhydrazine-induced intestinal tumors in rats. ( Borda, JT; Gimeno, EJ; Montenegro, MA; Sánchez Negrette, M, 2002) |
| " injections of 1,2-dimethylhydrazine (DMH) at a single dose of 21 mg/kg of body weight." | 3.69 | Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. ( Anisimov, VN; Popovich, IG; Zabezhinski, MA, 1997) |
| "Gut endocrine cells in a total of 122 intestinal-tract adenocarcinomas induced in inbred Wistar rats by 1,2-dimethylhydrazine dihydrochloride were examined histologically, ultrastructurally, and immunohistochemically for gastrin, somatostatin, vasoactive-intestinal polypeptide (VIP), and glicentin (enteroglucagon)." | 3.66 | Gut endocrine cells in rat intestinal-tract carcinoma induced by 1,2-dimethylhydrazine. ( Shimamoto, F; Tahara, E; Yanaihara, N, 1983) |
| " DMH was given to fish by intraperitoneal injection in a dosage of 15 mg/kg body weight once a week for 6 weeks." | 1.37 | [Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine]. ( Kakuta, I; Takase, K, 2011) |
| " The DMH was administered subcutaneously to six of the monkeys at a dosage of 25 mg/kg of body weight once a week for 16 weeks; control monkeys received an equivalent volume of the stock solution without DMH." | 1.31 | Failure to induce tumors in the large intestine of Capuchin mokeys (Cebus apella) by using 1,2-dimethylhydrazine. ( Borda, JT; Gimeno, EJ; Lertora, WJ; Montenegro, MA; Sánchez Negrette, M, 2000) |
| " weekly after the 1st 2 drug doses, the dosage as base being 9." | 1.29 | Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats. ( Gershbein, LL, 1993) |
| "The incidence of intestinal cancer in each group was compared." | 1.29 | Effect of selenium on 1,2-dimethylhydrazine-induced intestinal cancer in rats. ( Ho, YS; Jao, SW; Lee, W; Shen, KL, 1996) |
| "Melatonin was also shown to inhibit carcinogenesis in the small intestine." | 1.29 | [Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats]. ( Anisimov, VN; Muratov, EI; Popovich, IG, 1996) |
| "In this experiment, vitamin E deficiency reduced tumor incidence and calcium supplementation reduced tumor burden, with a significant interaction of the two." | 1.28 | The influence of dietary vitamin E and calcium status on intestinal tumors in rats. ( McIntosh, GH, 1992) |
| "The incidence of intestinal cancer in the control group (dimethylhydrazine only) was 91 percent; in groups provided with inorganic germanium one month before and during dimethylhydrazine treatment, and during dimethylhydrazine treatment only, it was 91 and 78 percent; in groups provided with organic germanium one month before and during dimethylhydrazine treatment, and during dimethylhydrazine treatment only, it was 64 and 64 percent; in groups provided with natural organic germanium one month before and during dimethylhydrazine treatment and during dimethylhydrazine treatment only, it was 50 and 45 percent." | 1.28 | Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats. ( Ho, YS; Jao, SW; Lee, W, 1990) |
| "Potassium chloride was provided in the drinking water one week before the first DMH treatment and was continued until sacrifice 14 weeks after the last DMH treatment." | 1.28 | Potassium inhibition of DMH-induced small intestinal tumors in rats. ( Jacobs, MM, 1990) |
| " Body weight data did not suggest any overt toxic effect of long-term administration of InsP6, Ins or InsP6 + Ins." | 1.28 | Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice. ( Chakravarthy, AK; Shamsuddin, AM; Ullah, A, 1989) |
| "Cimetidine is a histamine type 2 receptor antagonist and indomethacin is an inhibitor of prostaglandin synthesis." | 1.27 | Effects of cimetidine and indomethacin on the growth of dimethylhydrazine-induced or transplanted intestinal cancers in the rat. ( Caignard, A; Martin, F; Martin, M; Reisser, D; Thomas, B, 1984) |
| "Microcarcinomas are considered as initial stages of endocrine cell carcinoma." | 1.27 | Changes in intestinal mucosa above lymph follicles during carcinogenesis in rats. A light and electron microscopic study. ( Shimamoto, F; Vollmer, E, 1987) |
| "Rats of 3 inbred strains (DA, HS and AS2) were dosed with 1,2-dimethylhydrazine 2HCl (DMH) or saline by gavage weekly for 10 wk." | 1.26 | The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine. ( Gavin, JB; Herdson, PB; Teague, CA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (51.25) | 18.7374 |
| 1990's | 30 (37.50) | 18.2507 |
| 2000's | 8 (10.00) | 29.6817 |
| 2010's | 1 (1.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takase, K | 1 |
| Kakuta, I | 1 |
| Hirose, M | 3 |
| Yamaguchi, T | 1 |
| Mizoguchi, Y | 1 |
| Akagi, K | 2 |
| Futakuchi, M | 2 |
| Shirai, T | 3 |
| Montenegro, MA | 2 |
| Sánchez Negrette, M | 2 |
| Gimeno, EJ | 2 |
| Borda, JT | 2 |
| Blum, CA | 1 |
| Tanaka, T | 2 |
| Zhong, X | 1 |
| Li, Q | 1 |
| Dashwood, WM | 1 |
| Pereira, C | 1 |
| Xu, M | 1 |
| Dashwood, RH | 1 |
| Wedemeyer, J | 1 |
| Galli, SJ | 1 |
| Sengottuvelan, M | 1 |
| Senthilkumar, R | 1 |
| Nalini, N | 1 |
| Talmadge, JE | 1 |
| Hood, KC | 1 |
| Zobel, LC | 1 |
| Shafer, LR | 1 |
| Coles, M | 1 |
| Toth, B | 2 |
| Shimamoto, F | 2 |
| Tahara, E | 1 |
| Yanaihara, N | 1 |
| Takemiya, M | 2 |
| Miyayama, H | 2 |
| Takeuchi, T | 2 |
| Teague, CA | 1 |
| Gavin, JB | 1 |
| Herdson, PB | 1 |
| Stevens, RH | 2 |
| Loven, DP | 1 |
| Singh, D | 1 |
| Freeman, HJ | 2 |
| Spiller, GA | 1 |
| Kim, YS | 1 |
| Matveev, VV | 2 |
| Melikiants, AG | 2 |
| Hladík, V | 1 |
| Choluj, B | 1 |
| Vozenílek, J | 1 |
| Melikiants, LM | 1 |
| Caignard, A | 1 |
| Martin, M | 1 |
| Reisser, D | 1 |
| Thomas, B | 1 |
| Martin, F | 3 |
| Senior, PV | 1 |
| Sunter, JP | 1 |
| Appleton, DR | 1 |
| Watson, AJ | 1 |
| Patil, K | 1 |
| Decaëns, C | 2 |
| Rosa, B | 1 |
| Bara, J | 2 |
| Daher, N | 2 |
| Burtin, P | 2 |
| Faustov, LA | 1 |
| Morgenstern, L | 1 |
| Amodeo, P | 1 |
| Vimadalal, S | 1 |
| Scudamore, CH | 1 |
| Mizutani, T | 2 |
| Mitsuoka, T | 1 |
| Martin, MS | 3 |
| Justrabo, E | 2 |
| Olsson, NO | 1 |
| Leclerc, A | 2 |
| Pozharisski, KM | 1 |
| Klimashevski, VF | 1 |
| Gushchin, VA | 1 |
| Kawaura, A | 1 |
| Shibata, M | 1 |
| Togei, K | 1 |
| Otsuka, H | 1 |
| Jeannin, JF | 1 |
| Turusov, VS | 3 |
| Lanko, NS | 1 |
| Parfenov, IuD | 1 |
| Yamamoto, I | 2 |
| Maruyama, H | 2 |
| Moriguchi, M | 1 |
| Hasegawa, R | 1 |
| Tanaka, H | 1 |
| Tamano, S | 1 |
| Nagao, M | 1 |
| Sugimura, T | 1 |
| Ito, N | 2 |
| Hirata, K | 1 |
| Itoh, H | 1 |
| Nagata, N | 1 |
| Kuroda, Y | 1 |
| Ohsato, K | 1 |
| Yin, P | 1 |
| Zhao, J | 1 |
| Cheng, S | 1 |
| Zhu, Q | 1 |
| Liu, Z | 1 |
| Zhengguo, L | 1 |
| Gershbein, LL | 2 |
| Hoshiya, T | 1 |
| Takahashi, S | 2 |
| Hara, Y | 1 |
| McIntosh, GH | 4 |
| Jorgensen, L | 1 |
| Royle, P | 1 |
| Aoe, S | 1 |
| Oda, T | 1 |
| Tojima, T | 1 |
| Tanaka, M | 1 |
| Tatsumi, K | 1 |
| Alink, GM | 2 |
| Kuiper, HA | 1 |
| Hollanders, VM | 2 |
| Koeman, JH | 2 |
| Davidson, NO | 1 |
| Ifkovits, CA | 1 |
| Skarosi, SF | 1 |
| Hausman, AM | 1 |
| Llor, X | 1 |
| Sitrin, MD | 1 |
| Montag, A | 1 |
| Brasitus, TA | 1 |
| Ando, Y | 1 |
| Watanabe, H | 1 |
| Tatematsu, M | 1 |
| Hirano, K | 1 |
| Furihata, C | 1 |
| Fujimoto, N | 1 |
| Toge, T | 1 |
| Ito, A | 1 |
| Jao, SW | 2 |
| Shen, KL | 1 |
| Lee, W | 2 |
| Ho, YS | 2 |
| Le Leu, RK | 1 |
| Royle, PJ | 2 |
| Young, GP | 1 |
| Anisimov, VN | 4 |
| Popovich, IG | 4 |
| Muratov, EI | 1 |
| Rijnkels, JM | 1 |
| Woutersen, RA | 1 |
| Zabezhinski, MA | 2 |
| Denis, MG | 1 |
| Zabezhinskiĭ, MA | 1 |
| Liberman, AI | 1 |
| Shmidt, JL | 2 |
| Berstein, LM | 1 |
| Kovalenko, IG | 1 |
| Lieberman, AI | 1 |
| Steffensen, IL | 1 |
| Paulsen, JE | 1 |
| Engeset, D | 1 |
| Kronberg, L | 1 |
| Alexander, J | 1 |
| Balansky, R | 1 |
| Gyosheva, B | 1 |
| Ganchev, G | 1 |
| Mircheva, Z | 1 |
| Minkova, S | 1 |
| Georgiev, G | 1 |
| Playne, MJ | 1 |
| Lertora, WJ | 1 |
| Imaida, K | 1 |
| Ogawa, K | 1 |
| Asamoto, M | 1 |
| Miki, T | 1 |
| Ferré, J | 1 |
| Cuervas-Mons, M | 1 |
| Morte, L | 1 |
| Martínez, A | 1 |
| Ramón y Cajal, S | 1 |
| Altmann, GG | 1 |
| Lala, PK | 1 |
| Jacobs, MM | 1 |
| Berdinskikh, NK | 1 |
| Ignatenko, NA | 1 |
| Zaletok, SP | 1 |
| Beniashvili, DSh | 1 |
| Sharashidze, LK | 1 |
| Krutovskikh, VA | 2 |
| Turkiia, NG | 1 |
| Sartaniia, MS | 1 |
| Shamsuddin, AM | 1 |
| Ullah, A | 1 |
| Chakravarthy, AK | 1 |
| Fil'chenko, AA | 1 |
| Garmanchuk, LV | 3 |
| Ivashchenko, IuD | 3 |
| Bykorez, AI | 3 |
| Gautier, R | 1 |
| Nelson, RL | 1 |
| Wilson, W | 1 |
| Samelson, SL | 1 |
| Khoobyarian, N | 1 |
| Wilpart, M | 2 |
| Roberfroid, M | 2 |
| Cole, DA | 1 |
| Lindholm, PA | 1 |
| Cheng, HF | 1 |
| Sano, T | 1 |
| Remvikos, Y | 1 |
| Vielh, P | 1 |
| Buisson, JP | 1 |
| Manceau, R | 1 |
| Salmon, RJ | 1 |
| Reddy, BS | 1 |
| Quaroni, A | 1 |
| Weiser, MM | 1 |
| Lee, S | 1 |
| Amodeo, D | 1 |
| Gut, IT | 2 |
| Osipova, LA | 1 |
| Hammann, A | 1 |
| Speder, A | 1 |
| Vollmer, E | 1 |
| Sumiyoshi, H | 2 |
| Troianovskiĭ, SM | 1 |
| Smirnova, IO | 1 |
2 reviews available for 1,2-dimethylhydrazine and Cancer of Intestines
| Article | Year |
|---|---|
[Changes in the epithelial permeability of the large intestine of mice in the process of carcinogenesis].
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport, Active; Carc | 1983 |
Characterization, cloning and expression of the Tage4 gene, a member of the immunoglobulin superfamily.
Topics: 1,2-Dimethylhydrazine; Animals; Antigens, Neoplasm; Chromosome Mapping; Chromosomes, Human, Pair 19; | 1998 |
78 other studies available for 1,2-dimethylhydrazine and Cancer of Intestines
| Article | Year |
|---|---|
[Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Infective Agents; Antimetabolites, Antineoplastic; Blood Cell C | 2011 |
Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogenicity Tests | 2002 |
Effects of high molybdenum intake on 1,2-dimethylhydrazine-induced intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cell Division; Diet; Intestinal Neoplasms; Male; Molybd | 2002 |
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
Topics: 1,2-Dimethylhydrazine; Animals; Base Sequence; beta Catenin; Carcinogens; Codon; Colonic Neoplasms; | 2003 |
Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors.
Topics: 1,2-Dimethylhydrazine; Animals; Bone Marrow Transplantation; Carcinogens; Cell Proliferation; Diseas | 2005 |
Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Catalase; Diet; Glutathione; Intestinal Neoplasms; Lip | 2006 |
Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion.
Topics: 1,2-Dimethylhydrazine; Adjuvants, Immunologic; Animals; Anticarcinogenic Agents; Arginase; Breast Ne | 2007 |
Gut endocrine cells in rat intestinal-tract carcinoma induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Chromaffin System; Dimethylhydrazines; | 1983 |
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. II. Histochemical and ultrastructural characteristics of glycoproteins of 1,2-dimethylhydrazine-induced carcinoma cells.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Dimethylhydrazines; Glycop | 1982 |
The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Dimet | 1981 |
Adenosine and guanosine 3',5' cyclic monophosphate phosphodiesterase activities in rat small and large bowel following single and multiple exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Ani | 1981 |
Pathogenesis of 1,2-dimethylhydrazine-induced carcinomas in rat intestine. I. The induction of mucin producing carcinomas in rat intestine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Cecal Neoplasms; Colonic N | 1982 |
Effect of high hemicellulose corn bran in 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Diet; Dietary Fiber; Dimethylhydrazines; Intestinal Neo | 1984 |
[The effect of appendectomy and cholecystectomy on the origin and development of carcinoma of the large intestine and rectum].
Topics: 1,2-Dimethylhydrazine; Animals; Appendectomy; Carcinogens; Cholecystectomy; Dimethylhydrazines; Fema | 1984 |
[Kinetic characteristics of the normal enterocyte population and in carcinogenesis].
Topics: 1,2-Dimethylhydrazine; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Dimet | 1984 |
Effects of cimetidine and indomethacin on the growth of dimethylhydrazine-induced or transplanted intestinal cancers in the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Colonic | 1984 |
Are there diurnal fluctuations in crypt length and crypt cell birth rate in the intestines of normal and carcinogen-treated rats?
Topics: 1,2-Dimethylhydrazine; Animals; Biometry; Carcinogens; Cell Division; Circadian Rhythm; Dimethylhydr | 1984 |
Enhancing effect of vitamin E on murine intestinal tumorigenesis by 1,2-dimethylhydrazine dihydrochloride.
Topics: 1,2-Dimethylhydrazine; Anal Gland Neoplasms; Animals; Cecal Neoplasms; Colonic Neoplasms; Diet; Dime | 1983 |
Effect of 13 cis retinoic acid on early precancerous antigenic goblet-cell modifications and induction of cancer during 1,2-dimethylhydrazine carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1983 |
[Pathomorphology of endocrine glands during the latent period of experimental intestinal carcinogenesis].
Topics: 1,2-Dimethylhydrazine; Adrenal Cortex; Animals; Dimethylhydrazines; Endocrine Glands; Female; Hypoth | 1983 |
Effects of choledochojejunostomy with Roux-en-Y exclusion on dimethylhydrazine induced neoplasms in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Bile; Colonic Neoplasms; Common Bile Duct; Dimethylh | 1984 |
Effects of small bowel transection, resection, or bypass in 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Feces; Gastroint | 1983 |
Effect of Konjac mannan on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethy | 1983 |
[Hemoccult and experimental intestinal tumours (author's transl)].
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; False Negative Reactions; Gastrointestinal Hemor | 1981 |
Study of kinetics of epithelial cell populations in normal tissues of the rat's intestines and in carcinogenesis. III. Changes in kinetics of enterocyte populations in the course of experimental intestinal tumour induction in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Dimethylhydrazines; Epithelial Cells; Ileum; Intestinal Neopl | 1982 |
Effect of dietary degraded carrageenan on intestinal carcinogenesis in rats treated with 1,2-dimethylhydrazine dihydrochloride.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Carrageenan; Dietary Carbohydrates; Dimethylhydrazines; | 1982 |
Effect of dietary chenodeoxycholic acid on intestinal carcinogenesis induced by 1.2 dimethylhydrazine in mice and hamsters.
Topics: 1,2-Dimethylhydrazine; Animals; Chenodeoxycholic Acid; Cricetinae; Diet; Dimethylhydrazines; Drug Sy | 1981 |
[Effect of age on induction of intestinal tumors in mice by 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Age Factors; Animals; Carcinogens; Dimethylhydrazines; Intestinal Neoplasms; | 1981 |
Effect of beta-carotene, sodium ascorbate and cellulose on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Ascorbic Acid; beta Carotene; Body Weight; | 1994 |
Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Diethylnitro | 1994 |
Experimental carcinogenesis in the rat intestine induced by two different carcinogens--evaluation of carcinogenic action and its effect on ornithine decarboxylase activity.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Carcinogens; Dimethylhyd | 1994 |
Experimental studies of the inhibitory effects of green tea catechin on mice large intestinal cancers induced by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Adenosquamous; Cate | 1994 |
Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colon; Colonic Neoplasms; | 1993 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitr | 1993 |
The potential of an insoluble dietary fiber-rich source from barley to protect from DMH-induced intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Cholesterol; Dietary Fiber; Dimethylhydrazines; Hordeum; Intestinal | 1993 |
Effects of rice bran hemicellulose on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: 1,2-Dimethylhydrazine; Acids; Animals; Body Weight; Carcinogens; Cecum; Dimethylhydrazines; Hydrogen | 1993 |
Effect of heat processing and of vegetables and fruit in human diets on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; Dimethylhydrazine | 1993 |
Tissue and cell-specific patterns of expression of rat liver and intestinal fatty acid binding protein during development and in experimental colonic and small intestinal adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Carrier Proteins; Colon; Colonic Neopla | 1993 |
Gastric tumorigenicity of 1,2-dimethylhydrazine on the background of gastric intestinal metaplasia induced by X-irradiation in CD (SD) rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Gastric Mucosa; Intestinal Neoplasm | 1996 |
Effect of selenium on 1,2-dimethylhydrazine-induced intestinal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Disease Models, Animal; Drug Evalua | 1996 |
A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Body Weight; Butyrates; Butyric Acid; Carcino | 1996 |
[Effect of melatonin on 1,2-dimethylhydrazine-induced intestinal tumors in rats].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1996 |
Interaction of dietary fat and of a vegetables/fruit mixture on 1,2-dimethylhydrazine- or N-methyl-N'-nitro-N-nitrosoguanidine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Colorectal Neoplasms; Dietary | 1997 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neopla | 1997 |
[Effect of the enterosorbent Aqualen on intestinal carcinogenesis induced by 1,2-dimethylhydrazine in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Colorectal Neoplasms; Enterosorption; Femal | 1998 |
Prevention of spontaneous and chemically induced carcinogenesis using activated carbon fiber adsorbent. III. Inhibitory effect of the activated carbon fiber adsorbent 'Aqualen' on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adsorption; Animals; Blood Glucose; Carbon; Carcinogens; Cholesterol; Dietary | 1999 |
The drinking water chlorination by-products 3,4-dichloro-5-hydroxy-2[5H]-furanone(mucochloric acid) and 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone do not induce preneoplastic or neoplastic intestinal lesions in F344 rats, balb/ca mice or C57bl/6
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Furans; Intestinal Neoplasms; Male; Mice; Mice, Inbred | 1999 |
Inhibitory effects of freeze-dried milk fermented by selected Lactobacillus bulgaricus strains on carcinogenesis induced by 1,2-dimethylhydrazine in rats and by diethylnitrosamine in hamsters.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Biological Therapy; Body Weight; Carcinogen | 1999 |
A probiotic strain of L. acidophilus reduces DMH-induced large intestinal tumors in male Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Fatty A | 1999 |
Failure to induce tumors in the large intestine of Capuchin mokeys (Cebus apella) by using 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cebus; Hyperplasia; Injections, Subcutaneous; Intestina | 2000 |
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animal Feed; Animals; Carcinogens; Colonic Neoplasms; DNA Add | 2002 |
[The action of 5-fluorouracil in DMH-induced carcinogenesis in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Disease Models, Animal; Drug Evalua | 1992 |
The influence of dietary vitamin E and calcium status on intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Calcium, Dietary; Dietary Fats; Dimethylhydrazines; Ene | 1992 |
The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Dimet | 1991 |
Control of 1,2-dimethylhydrazine-induced crypt hyperplasia by natural-killer cells and its relevance to carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Division; Dimethylhydrazines; Hyperplasia; Intesti | 1991 |
Effect of germanium on 1,2-dimethylhydrazine-induced intestinal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Animals; Carcinogens; Dimethylhydra | 1990 |
Potassium inhibition of DMH-induced small intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; Drinking; Glutathione Transferase; Hematologic T | 1990 |
[Ornithine decarboxylase activity and polyamine contents in 1,2-dimethylhydrazine-induced carcinogenesis of the intestines in rats].
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; Intestinal Mucosa; Intestinal Neoplasms; Intesti | 1990 |
[The induction of cancer of the large intestine in Macaca fascicularis monkeys with 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Dimethylhydrazines; Dose-Response Relat | 1990 |
Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cell Division; Dimethylhydrazines; Inosito | 1989 |
[The production of epidermal growth factor and polypeptides similar to it in the intestinal mucosa of rats in 1,2-dimethylhydrazine-induced carcinogenesis and compensatory regeneration].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Chromatography, High Pressure Liquid; Dimethylhydrazine | 1989 |
Induction of rat intestinal carcinogenesis with single doses, low and high repeated doses of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinoma; Dimethylhydrazines; Dose-Response Relationship, Drug; Dru | 1989 |
The interaction of retrovirus and chemical carcinogen in experimental colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1987 |
Intestinal carcinogenesis and dietary fibers: the influence of cellulose or Fybogel chronically given after exposure to DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Bicarbonates; Body Weight; Cellulose; Citrates; Citric Acid; Colonic | 1987 |
Identification of environmental carcinogens utilizing T-cell mediated immunity.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Carcinogens, Environment | 1986 |
DNA ploidy in 1,2-dimethylhydrazine-induced rat tumors.
Topics: 1,2-Dimethylhydrazine; Animals; Dimethylhydrazines; DNA; Flow Cytometry; Intestinal Neoplasms; Male; | 1988 |
Interactions of selenium deficiency, vitamin E, polyunsaturated fat, and saturated fat on azoxymethane-induced colon carcinogenesis in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Azoxymethane; Colonic Neoplasms; Dietary Fa | 1986 |
Expression of developmentally regulated crypt cell antigens in human and rat intestinal tumors.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antigens; Carcinoembryonic A | 1986 |
[Characteristics of the epidermal growth factor receptors in the epithelium of the gastrointestinal tract of rats and in intestinal tumors induced by 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Membrane; Digestive System; Dimethylhydrazines; Ep | 1986 |
[Effect of the epidermal growth factor on 1,2-dimethylhydrazine-induced carcinogenesis in the rat intestinal mucosa].
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Dimethylhydrazines; Epidermal Growth Factor; Intesti | 1987 |
Gut-associated lymphoid tissue and 1,2-dimethylhydrazine intestinal tumors in the rat: an histological and immunoenzymatic study.
Topics: 1,2-Dimethylhydrazine; Animals; Antibodies, Monoclonal; Carcinogens; Colon; Dimethylhydrazines; Hist | 1986 |
Anti-initiation activity of N-acetylcysteine in experimental colonic carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1986 |
Changes in intestinal mucosa above lymph follicles during carcinogenesis in rats. A light and electron microscopic study.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinoma; Cecum; Colonic Neoplasms; Dimethylhydrazines; Duodenum; F | 1987 |
Effects of feeding regimen on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Dimethylhydrazines; Eating; Intestinal Neoplasms; Male; | 1985 |
[Immunomorphological study of 1,2-dimethylhydrazine-induced carcinomas of the large intestine in rats using monoclonal antibodies to intermediate filament proteins].
Topics: 1,2-Dimethylhydrazine; Animals; Antibodies, Monoclonal; Dimethylhydrazines; Fluorescent Antibody Tec | 1985 |
Effect of dietary seaweed preparations on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Carrageenan; Diet; Dimethylhydrazines; Intestinal Neopl | 1985 |
[Modifying action of neonatal androgenization on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA-strain mice].
Topics: 1,2-Dimethylhydrazine; Animals; Animals, Newborn; Dimethylhydrazines; Hemangiosarcoma; Intestinal Ne | 1985 |
Effects of vitamin E deficiency on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Carcinogens; Dimethylhydrazines; Intestinal | 1985 |