1,2-dimethylhydrazine has been researched along with Cancer of Duodenum in 7 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Weekly injections of dimethylhydrazine (DMH) (25 mg/kg), or azoxymethane (AOM) (8 mg/kg) to young adult male CDI mice for 1-2 months produced generalized intestinal crypt hyperplasia, which we measured in duodenum in terms of number of interphase and mitotic cells present in crypts." | 3.69 | Initiated stem cells in murine intestinal carcinogenesis: prolonged survival, control by NK cells, and progression. ( Altmann, GG; Lala, PK, 1994) |
| " The present study examined whether NK cells control 1,2-dimethylhydrazine (DMH)-induced hyperplasia of the duodenal crypt in CD1 mice." | 3.68 | Hyperplasia of mouse duodenal crypts and its control by NK cells during the initial phase of DMH carcinogenesis. ( Altmann, GG; Lala, PK; Parhar, RS, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toth, B | 1 |
| Patil, K | 1 |
| Snow, AD | 1 |
| Altmann, GG | 3 |
| Jagadeesan, V | 1 |
| Rao, NJ | 1 |
| Sesikeran, B | 1 |
| Lala, PK | 2 |
| Futakuchi, M | 1 |
| Hirose, M | 1 |
| Imaida, K | 1 |
| Takahashi, S | 1 |
| Ogawa, K | 1 |
| Asamoto, M | 1 |
| Miki, T | 1 |
| Shirai, T | 1 |
| Parhar, RS | 1 |
| Ito, A | 1 |
| Watanabe, H | 1 |
| Aoyama, H | 1 |
| Nakagawa, Y | 1 |
| Mori, M | 1 |
7 other studies available for 1,2-dimethylhydrazine and Cancer of Duodenum
| Article | Year |
|---|---|
Enhancing effect of vitamin E on murine intestinal tumorigenesis by 1,2-dimethylhydrazine dihydrochloride.
Topics: 1,2-Dimethylhydrazine; Anal Gland Neoplasms; Animals; Cecal Neoplasms; Colonic Neoplasms; Diet; Dime | 1983 |
Time-related increase of nucleolar size and villus cell number during DMH carcinogenesis in the rat duodenal epithelium.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cell Count; Cell Nucleolus; Dimethylhydrazines; Duodena | 1983 |
Effect of iron deficiency on DMH-induced gastrointestinal tract tumors and occurrence of hepatocyte abnormalities in Fischer rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazi | 1994 |
Initiated stem cells in murine intestinal carcinogenesis: prolonged survival, control by NK cells, and progression.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Brunner Glands; Cell Survival; Cell Transformation, Ne | 1994 |
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animal Feed; Animals; Carcinogens; Colonic Neoplasms; DNA Add | 2002 |
Hyperplasia of mouse duodenal crypts and its control by NK cells during the initial phase of DMH carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Dose-Response Relationship, Drug; D | 1990 |
Effect of 1,2-dimethylhydrazine and hydrogen peroxide for the duodenal tumorigenesis in relation to blood catalase activity in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Catalase; Cocarcinogenesis; Dimethylhydrazines; Duodenal Neoplasms; | 1986 |