1,2-dimethylhydrazine has been researched along with Body Weight in 119 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phytic acid (PA) has been demonstrated to have a potent anticarcinogenic activity against colorectal cancer (CRC)." | 7.88 | Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model. ( Chen, C; Cheng, L; Li, X; Liu, C; Song, Y; Yang, F, 2018) |
| " The present study was carried out to divulge the protective potential of the probiotic Dahi containing Lactobacillus acidophilus LaVK2 and Bifidobacterium bifidum BbVK3 alone or in combination with piroxicam (PXC) on the development of early biomarkers of colorectal carcinogenesis in male Wistar rats administered 1,2-dimethylhydrazine (DMH)." | 7.80 | Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats. ( Kansal, VK; Kruzliak, P; Kumari, A; Mohania, D, 2014) |
| "The present study has aimed to evaluate chemopreventive potential of d-carvone on oxidative stress markers, biotransforming enzymes, incidence of colonic polyps and aberrant crypt foci (ACF) in 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis." | 7.79 | Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis. ( Balasubramanian, T; Kabalimoorthy, J; Nalini, N; Sudha, M; Vinothkumar, R; Viswanathan, P, 2013) |
| "In many developed countries, colorectal cancer is a leading cause of morbidity and mortality and its etiology is familiar to be a grouping of nutritional and environmental factors, less physical activity and hereditary factors." | 5.72 | Anti-inflammatory and Antioxidant Effect of Lycoperoside H against the 1,2-Dimethyl Hydrazine (DMH) Induced Colorectal Cancer in Rats. ( Liu, Y; Qi, X, 2022) |
| " Therefore, the authors studied whether long-term administration of the DPP4i Sitagliptin (SITA) affects 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis." | 5.39 | Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats. ( Caderni, G; Femia, AP; Lodovici, M; Maglieri, G; Mannucci, E; Raimondi, L, 2013) |
| " weekly after the 1st 2 drug doses, the dosage as base being 9." | 5.29 | Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats. ( Gershbein, LL, 1993) |
| "Tegafur was effective, but levamisole with or without tegafur was not effective against early cancer." | 5.27 | Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers. ( Aoki, N; Hamada, S; Hirayama, R; Matsumura, J; Mishima, Y; Miyanaga, T; Takagi, Y, 1985) |
| "Phytic acid (PA) has been demonstrated to have a potent anticarcinogenic activity against colorectal cancer (CRC)." | 3.88 | Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model. ( Chen, C; Cheng, L; Li, X; Liu, C; Song, Y; Yang, F, 2018) |
| " The present study was carried out to divulge the protective potential of the probiotic Dahi containing Lactobacillus acidophilus LaVK2 and Bifidobacterium bifidum BbVK3 alone or in combination with piroxicam (PXC) on the development of early biomarkers of colorectal carcinogenesis in male Wistar rats administered 1,2-dimethylhydrazine (DMH)." | 3.80 | Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats. ( Kansal, VK; Kruzliak, P; Kumari, A; Mohania, D, 2014) |
| "The present study has aimed to evaluate chemopreventive potential of d-carvone on oxidative stress markers, biotransforming enzymes, incidence of colonic polyps and aberrant crypt foci (ACF) in 1,2-dimethylhydrazine (DMH)-induced experimental colon carcinogenesis." | 3.79 | Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis. ( Balasubramanian, T; Kabalimoorthy, J; Nalini, N; Sudha, M; Vinothkumar, R; Viswanathan, P, 2013) |
| " Eight weeks old Balb-C male mice received subcutaneous injections of 1,2-dimethylhydrazine (DMH) (20 mg/kg body weight) once a week for 12 weeks." | 3.79 | Influence of gilaburu (Viburnum opulus) juice on 1,2-dimethylhydrazine (DMH)-induced colon cancer. ( Canoz, O; Elmalı, F; Ertekin, T; Karaca, O; Nisari, M; Ulger, H; Unur, E, 2013) |
| " Groups 1, 3 and 5 were initiated by 1,2-dimethylhydrazine (DMH) 20 mg/kg body weight s." | 3.77 | Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action. ( Abou-Shafey, AE; Elgendy, SA; Masoud, AA; Salim, EI, 2011) |
| " Mice received intraperitoneal injections of 1,2-dimethylhydrazine (DMH) (40 mg/kg body weight) once a week for 6 weeks to selectively induce aberrant crypt foci (ACF) and tumors in the colon." | 3.75 | IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis. ( Diehl, D; Elmlinger, M; Göttlicher, M; Hessel, E; Hoeflich, A; Lahm, H; Langhammer, M; Oesterle, D; Renner-Müller, I; Wolf, E, 2009) |
| " Intestinal tumors were induced by 1,2-dimethylhydrazine (DMH) given subcutaneously as 16 weekly doses at 20 mg/kg body weight." | 3.71 | Effects of high molybdenum intake on 1,2-dimethylhydrazine-induced intestinal tumors in rats. ( Borda, JT; Gimeno, EJ; Montenegro, MA; Sánchez Negrette, M, 2002) |
| " injections of 1,2-dimethylhydrazine (DMH) at a single dose of 21 mg/kg of body weight." | 3.69 | Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. ( Anisimov, VN; Popovich, IG; Zabezhinski, MA, 1997) |
| " 1,2-dimethylhydrazine (DMH) was administered (20 mg/kg body weight) in 20 weekly i." | 3.67 | Effect of dietary selenium deficiency on incidence and size of 1,2-dimethylhydrazine-induced colon tumors in rats. ( Buddingh, F; Pence, BC, 1985) |
| " Colon tumors were induced with 16 weekly injections of 1,2-dimethylhydrazine (DMH, 10 mg/kg body weight)." | 3.67 | Co-carcinogenic effect of carbon black ingestion with dietary fat on the development of colon tumors in rats. ( Buddingh, F; Pence, BC, 1987) |
| "5% corn oil or lard 2 weeks before, during, and until 1 week after sc injection of 15 mg azoxymethane [(AOM) CAS: 25843-45-2]/kg body weight, once weekly for 2 weeks (designated as initiation)." | 3.67 | Effect of different levels of dietary corn oil and lard during the initiation phase of colon carcinogenesis in F344 rats. ( Maruyama, H; Reddy, BS, 1986) |
| "After simulation of colon cancer, the animals were intragastricly administered entorosorbent at a dose of 1 ml of suspension (corresponding to 0." | 1.72 | Evaluation of membrane-destructive processes in rats with induced carcinogenesis of the colon using the cytostatic vincristine. ( Fira, D; Fira, L; Garlitska, N; Kachur, O; Lykhatskyі, P, 2022) |
| "In many developed countries, colorectal cancer is a leading cause of morbidity and mortality and its etiology is familiar to be a grouping of nutritional and environmental factors, less physical activity and hereditary factors." | 1.72 | Anti-inflammatory and Antioxidant Effect of Lycoperoside H against the 1,2-Dimethyl Hydrazine (DMH) Induced Colorectal Cancer in Rats. ( Liu, Y; Qi, X, 2022) |
| "Colon cancer is the third leading cause of cancer mortality worldwide, which results from interactions of different factors." | 1.43 | Exenatide suppresses 1,2-dimethylhydrazine-induced colon cancer in diabetic mice: Effect on tumor angiogenesis and cell proliferation. ( Mohamed, MI; Tawfik, MK, 2016) |
| " Therefore, the authors studied whether long-term administration of the DPP4i Sitagliptin (SITA) affects 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis." | 1.39 | Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats. ( Caderni, G; Femia, AP; Lodovici, M; Maglieri, G; Mannucci, E; Raimondi, L, 2013) |
| "To investigate the anti-colon cancer effects of berberine and possible relationship with cyclooxygenase-2." | 1.36 | [Preventive effects of berberine on experimental colon cancer and relationship with cyclooxygenase-2 expression]. ( Wu, K; Yang, J; Zhou, Q, 2010) |
| "Treatment with lycopene, synbiotic or their combination significantly increased apoptosis, reduced the PCNA and p53 labeling indexes and the development of classical ACF and mucin-negative ACF." | 1.36 | Effects of lycopene, synbiotic and their association on early biomarkers of rat colon carcinogenesis. ( Barbisan, LF; Dias, MC; Gomes, MI; Rodrigues, MA; Salvadori, DM; Vieiralves, NF, 2010) |
| "They suggest that Ca can reduce colorectal cancer risk in meat-eaters." | 1.35 | Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium. ( Corpet, DE; Guéraud, F; Pierre, F; Santarelli, R; Taché, S, 2008) |
| "Treatment with vanadium in the form of ammonium monovanadate supplemented ad libitum in drinking water for the entire experimental period caused a significant (p<0." | 1.33 | Vanadium inhibits DNA-protein cross-links and ameliorates surface level changes of aberrant crypt foci during 1,2-dimethylhydrazine induced rat colon carcinogenesis. ( Chatterjee, M; Kanna, PS; Samanta, K; Saralaya, MG, 2005) |
| "To study the effects of PSC on liver cancer development, a daily dose of 30 mg PSC/kg body wt (PSC30) was chosen based on an initial dose-response experiment." | 1.32 | Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats. ( Bradley, G; Kankesan, J; Laconi, E; Ling, V; Rajalakshmi, S; Rao, PM; Sarma, DS; Thiessen, JJ; Vanama, R; Yusuf, A, 2003) |
| "Vanadium-treated rats significantly reduced (P < 0." | 1.32 | Vanadium inhibits placental glutathione S-transferase (GST-P) positive foci in 1,2-dimethyl hydrazine induced rat colon carcinogenesis. ( Chakraborty, P; Chatterjee, M; Datta, S; Hemalatha, P; Kanna, PS; Mahendrakumar, CB, 2003) |
| " weekly after the 1st 2 drug doses, the dosage as base being 9." | 1.29 | Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats. ( Gershbein, LL, 1993) |
| "3% wt/wt) and were then dosed orally with a human fecal suspension." | 1.29 | The effect of lactulose on DNA damage induced by DMH in the colon of human flora-associated rats. ( Bearne, CA; Fischer, R; Pool-Zobel, BL; Rowland, IR, 1996) |
| "In this experiment, vitamin E deficiency reduced tumor incidence and calcium supplementation reduced tumor burden, with a significant interaction of the two." | 1.28 | The influence of dietary vitamin E and calcium status on intestinal tumors in rats. ( McIntosh, GH, 1992) |
| " Initial studies showed single-dose oral LD50 values (95% confidence intervals) of 26 (18-32) mg DMH-2HCl/kg body weight for males, and 60 (53-65) for females." | 1.28 | Dietary protein and chronic toxicity of 1,2-dimethylhydrazine fed to mice. ( Alster, JM; Anderson, PA; Clinton, SK; Imrey, PB; Mabry, FJ; Nandkumar, S; Simon, J; Thursh, DR; Truex, CR; Visek, WJ, 1991) |
| " Body weight data did not suggest any overt toxic effect of long-term administration of InsP6, Ins or InsP6 + Ins." | 1.28 | Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice. ( Chakravarthy, AK; Shamsuddin, AM; Ullah, A, 1989) |
| "05) was lost when these dosed groups were compared with temporal control groups." | 1.27 | Chronic effects of dietary exposure to amosite and chrysotile asbestos in Syrian golden hamsters. ( McConnell, EE; Moore, JA; Rust, JH; Shefner, AM, 1983) |
| "Colon cancers were confirmed histologically in every animal." | 1.27 | An investigation into the mechanism of co-carcinogenesis of dietary cholesterol during the induction of colon cancer in rats by 1,2 dimethylhydrazine. ( Clark, CG; Cruse, JP; Lewin, MR, 1984) |
| "This finding may have relevance to colorectal cancer in man where razoxane has been used in disseminated disease and as an adjuvant to surgery." | 1.27 | Inhibition of experimental colorectal cancer by razoxane (ICRF-159). ( Gilbert, JM; Kark, AE; Slavin, G; Thompson, EM, 1984) |
| " The inhibitory effect depended upon dosage to some extent." | 1.27 | [Effect of ascorbic acid on the induction of uterine sarcomas in mice]. ( Trukhanova, LS, 1987) |
| "Tegafur was effective, but levamisole with or without tegafur was not effective against early cancer." | 1.27 | Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers. ( Aoki, N; Hamada, S; Hirayama, R; Matsumura, J; Mishima, Y; Miyanaga, T; Takagi, Y, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (29.41) | 18.7374 |
| 1990's | 32 (26.89) | 18.2507 |
| 2000's | 31 (26.05) | 29.6817 |
| 2010's | 19 (15.97) | 24.3611 |
| 2020's | 2 (1.68) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Qi, X | 1 |
| Kachur, O | 1 |
| Fira, L | 1 |
| Lykhatskyі, P | 1 |
| Fira, D | 1 |
| Garlitska, N | 1 |
| Liu, C | 1 |
| Chen, C | 1 |
| Yang, F | 1 |
| Li, X | 1 |
| Cheng, L | 1 |
| Song, Y | 1 |
| López-Mejia, A | 1 |
| Ortega-Pérez, LG | 1 |
| Godinez-Hernández, D | 1 |
| Nateras-Marin, B | 1 |
| Meléndez-Herrera, E | 1 |
| Rios-Chavez, P | 1 |
| Femia, AP | 1 |
| Raimondi, L | 1 |
| Maglieri, G | 1 |
| Lodovici, M | 1 |
| Mannucci, E | 1 |
| Caderni, G | 1 |
| Vinothkumar, R | 1 |
| Sudha, M | 1 |
| Viswanathan, P | 1 |
| Kabalimoorthy, J | 1 |
| Balasubramanian, T | 1 |
| Nalini, N | 3 |
| Mohania, D | 2 |
| Kansal, VK | 2 |
| Kumar, M | 1 |
| Nagpal, R | 1 |
| Yamashiro, Y | 1 |
| Marotta, F | 1 |
| Kruzliak, P | 1 |
| Kumari, A | 1 |
| Zhu, J | 1 |
| Zhu, C | 1 |
| Ge, S | 1 |
| Zhang, M | 1 |
| Jiang, L | 1 |
| Cui, J | 1 |
| Ren, F | 1 |
| Walia, S | 1 |
| Kamal, R | 1 |
| Kanwar, SS | 2 |
| Dhawan, DK | 5 |
| Nanda, N | 1 |
| Bhatia, A | 1 |
| Mahmood, A | 1 |
| Mahmood, S | 1 |
| Tawfik, MK | 1 |
| Mohamed, MI | 1 |
| Sharma, SH | 1 |
| Thulasingam, S | 1 |
| Chellappan, DR | 1 |
| Chinnaswamy, P | 1 |
| Nagarajan, S | 1 |
| Aranganathan, S | 1 |
| Selvam, JP | 1 |
| Diehl, D | 1 |
| Hessel, E | 1 |
| Oesterle, D | 1 |
| Renner-Müller, I | 1 |
| Elmlinger, M | 1 |
| Langhammer, M | 1 |
| Göttlicher, M | 1 |
| Wolf, E | 1 |
| Lahm, H | 1 |
| Hoeflich, A | 1 |
| Sangeetha, N | 1 |
| Felix, AJ | 1 |
| Ramzanighara, A | 1 |
| Ezzatighadi, F | 1 |
| Rai, DV | 1 |
| Chadha, VD | 1 |
| Dias, MC | 1 |
| Vieiralves, NF | 1 |
| Gomes, MI | 1 |
| Salvadori, DM | 1 |
| Rodrigues, MA | 1 |
| Barbisan, LF | 2 |
| Wu, K | 1 |
| Yang, J | 1 |
| Zhou, Q | 1 |
| Salim, EI | 2 |
| Abou-Shafey, AE | 1 |
| Masoud, AA | 1 |
| Elgendy, SA | 1 |
| Perše, M | 1 |
| Injac, R | 1 |
| Štrukelj, B | 1 |
| Cerar, A | 1 |
| Ulger, H | 1 |
| Ertekin, T | 1 |
| Karaca, O | 1 |
| Canoz, O | 1 |
| Nisari, M | 1 |
| Unur, E | 1 |
| Elmalı, F | 1 |
| Triolet, J | 1 |
| Shaik, AA | 1 |
| Gallaher, DD | 1 |
| O'Sullivan, MG | 1 |
| Xing, C | 1 |
| Jrah-Harzallah, H | 1 |
| Ben-Hadj-Khalifa, S | 1 |
| Almawi, WY | 1 |
| Maaloul, A | 1 |
| Houas, Z | 1 |
| Mahjoub, T | 1 |
| Verma, A | 1 |
| Shukla, G | 1 |
| Hirose, M | 8 |
| Yamaguchi, T | 1 |
| Mizoguchi, Y | 2 |
| Akagi, K | 3 |
| Futakuchi, M | 2 |
| Shirai, T | 5 |
| Poulsen, M | 1 |
| Mølck, AM | 1 |
| Jacobsen, BL | 1 |
| Montenegro, MA | 1 |
| Sánchez Negrette, M | 1 |
| Gimeno, EJ | 1 |
| Borda, JT | 1 |
| Onose, J | 1 |
| Imai, T | 2 |
| Hasumura, M | 2 |
| Ueda, M | 1 |
| Kankesan, J | 1 |
| Yusuf, A | 1 |
| Laconi, E | 1 |
| Vanama, R | 1 |
| Bradley, G | 1 |
| Thiessen, JJ | 1 |
| Ling, V | 1 |
| Rao, PM | 1 |
| Rajalakshmi, S | 1 |
| Sarma, DS | 1 |
| Kanna, PS | 2 |
| Mahendrakumar, CB | 1 |
| Chatterjee, M | 2 |
| Hemalatha, P | 1 |
| Datta, S | 1 |
| Chakraborty, P | 1 |
| Pickering, A | 1 |
| Chang, C | 1 |
| Vincent, JB | 1 |
| Popovich, IG | 3 |
| Zabezhinski, MA | 3 |
| Egormin, PA | 1 |
| Tyndyk, ML | 1 |
| Anikin, IV | 1 |
| Spasov, AA | 1 |
| Semenchenko, AV | 1 |
| Yashin, AI | 1 |
| Anisimov, VN | 4 |
| Saralaya, MG | 1 |
| Samanta, K | 1 |
| Kitamura, Y | 1 |
| Yamagishi, M | 1 |
| Okazaki, K | 1 |
| Umemura, T | 1 |
| Imazawa, T | 1 |
| Nishikawa, A | 2 |
| Matsumoto, W | 1 |
| Basterfield, L | 1 |
| Reul, JM | 1 |
| Mathers, JC | 1 |
| Dani, V | 1 |
| Goel, A | 1 |
| Vaiphei, K | 2 |
| Nehru, B | 1 |
| Sanyal, SN | 1 |
| Pierre, F | 1 |
| Santarelli, R | 1 |
| Taché, S | 1 |
| Guéraud, F | 1 |
| Corpet, DE | 1 |
| Cho, YM | 1 |
| Ota, Y | 1 |
| Takami, S | 1 |
| McConnell, EE | 2 |
| Shefner, AM | 1 |
| Rust, JH | 1 |
| Moore, JA | 2 |
| Rutter, HA | 1 |
| Ulland, BM | 1 |
| Cruse, JP | 2 |
| Lewin, MR | 2 |
| Clark, CG | 2 |
| Nutter, RL | 1 |
| Gridley, DS | 1 |
| Kettering, JD | 1 |
| Goude, AG | 1 |
| Slater, JM | 1 |
| Keller, WC | 1 |
| Olson, CT | 1 |
| Back, KC | 1 |
| Gaworski, CL | 1 |
| Metzger, U | 1 |
| Meier, J | 1 |
| Uhlschmid, G | 1 |
| Weihe, H | 1 |
| Gilbert, JM | 1 |
| Thompson, EM | 1 |
| Slavin, G | 1 |
| Kark, AE | 1 |
| Naito, Y | 1 |
| Scudamore, CH | 1 |
| Freeman, HJ | 1 |
| Mizutani, T | 2 |
| Mitsuoka, T | 1 |
| Nauss, KM | 4 |
| Locniskar, M | 3 |
| Newberne, PM | 4 |
| Gershbein, LL | 3 |
| Yamamoto, I | 1 |
| Maruyama, H | 2 |
| Moriguchi, M | 1 |
| Hasegawa, R | 1 |
| Tanaka, H | 1 |
| Tamano, S | 2 |
| Nagao, M | 1 |
| Sugimura, T | 2 |
| Ito, N | 4 |
| Mereto, E | 1 |
| Frencia, L | 1 |
| Ghia, M | 1 |
| Hoshiya, T | 2 |
| Takahashi, S | 1 |
| Hara, Y | 1 |
| Aoe, S | 1 |
| Oda, T | 1 |
| Tojima, T | 1 |
| Tanaka, M | 1 |
| Tatsumi, K | 1 |
| Beaty, MM | 1 |
| Lee, EY | 1 |
| Glauert, HP | 2 |
| Alink, GM | 2 |
| Kuiper, HA | 1 |
| Hollanders, VM | 2 |
| Koeman, JH | 2 |
| Takahashi, M | 1 |
| Minamoto, T | 1 |
| Yamashita, N | 1 |
| Yazawa, K | 1 |
| Esumi, H | 1 |
| McIntosh, GH | 3 |
| Le Leu, RK | 1 |
| Royle, PJ | 2 |
| Young, GP | 1 |
| Rowland, IR | 2 |
| Bearne, CA | 1 |
| Fischer, R | 1 |
| Pool-Zobel, BL | 1 |
| Carter, JW | 1 |
| Lancaster, H | 1 |
| Hardman, WE | 2 |
| Cameron, IL | 3 |
| Rijnkels, JM | 1 |
| Woutersen, RA | 1 |
| Hambly, RJ | 1 |
| Rumney, CJ | 1 |
| Cunninghame, M | 1 |
| Fletcher, JM | 1 |
| Rijken, PJ | 1 |
| Heitman, DW | 2 |
| Wanibuchi, H | 1 |
| Taniyama, T | 1 |
| Yano, Y | 1 |
| Morimura, K | 1 |
| Yamamoto, S | 1 |
| Otani, S | 1 |
| Nishizawa, Y | 1 |
| Morii, H | 1 |
| Fukushima, S | 1 |
| Tsukamura, M | 1 |
| Goto, H | 1 |
| Arisawa, T | 1 |
| Hayakawa, T | 1 |
| Nakai, N | 1 |
| Murakami, T | 1 |
| Fujitsuka, N | 1 |
| Shimomura, Y | 1 |
| Ishizuka, S | 1 |
| Kasai, T | 1 |
| Kim, DJ | 1 |
| Takasuka, N | 1 |
| Kim, JM | 1 |
| Sekine, K | 1 |
| Ota, T | 1 |
| Asamoto, M | 1 |
| Murakoshi, M | 1 |
| Nishino, H | 1 |
| Nir, Z | 1 |
| Tsuda, H | 1 |
| Dubina, MV | 1 |
| Petrishchev, NN | 1 |
| Balansky, R | 1 |
| Gyosheva, B | 1 |
| Ganchev, G | 1 |
| Mircheva, Z | 1 |
| Minkova, S | 1 |
| Georgiev, G | 1 |
| Playne, MJ | 1 |
| Kovalenko, AL | 1 |
| Spinardi-Barbisan, AL | 1 |
| Kaneno, R | 1 |
| Marchesan Rodrigues, MA | 1 |
| Fávero Salvadori, DM | 1 |
| Trindade Moreira, EL | 1 |
| Viana de Camargo, JL | 1 |
| Avivi-Green, C | 1 |
| Polak-Charcon, S | 1 |
| Madar, Z | 1 |
| Schwartz, B | 2 |
| Schleiffer, R | 1 |
| Duranton, B | 1 |
| Gossé, F | 1 |
| Hasselmann, M | 1 |
| Raul, F | 1 |
| Ingram, DM | 1 |
| Castleden, WM | 1 |
| Mokady, E | 1 |
| Shany, S | 1 |
| Lamprecht, SA | 1 |
| Kimoto, N | 1 |
| Iwata, T | 1 |
| Kasai, M | 1 |
| Nakamura, A | 1 |
| Liu, Z | 2 |
| Ishikawa, W | 1 |
| Huang, X | 1 |
| Tomotake, H | 1 |
| Kayashita, J | 1 |
| Watanabe, H | 3 |
| Kato, N | 2 |
| Hagiwara, A | 1 |
| Miyashita, K | 1 |
| Nakanishi, T | 1 |
| Sano, M | 1 |
| Kadota, T | 1 |
| Koda, T | 1 |
| Nakamura, M | 1 |
| Imaida, K | 1 |
| Uesaka, T | 2 |
| Lu, H | 1 |
| Kyo, E | 1 |
| Katoh, O | 1 |
| Nelson, RL | 1 |
| Briley, S | 1 |
| Vaz, OP | 1 |
| Abcarian, H | 1 |
| Karkare, MR | 1 |
| Clark, TD | 1 |
| Visek, WJ | 2 |
| Clinton, SK | 2 |
| Imrey, PB | 2 |
| Thursh, DR | 1 |
| Truex, CR | 2 |
| Alster, JM | 2 |
| Anderson, PA | 2 |
| Mabry, FJ | 1 |
| Nandkumar, S | 1 |
| Simon, J | 1 |
| McLellan, E | 1 |
| Bird, RP | 1 |
| Masuda, A | 1 |
| Kamano, K | 1 |
| Okuyama, H | 1 |
| Sumiyoshi, H | 2 |
| Wargovich, MJ | 1 |
| Kingsnorth, AN | 2 |
| LaMuraglia, GM | 1 |
| Ross, JS | 2 |
| Malt, RA | 2 |
| Ord, VA | 1 |
| Hunter, KE | 1 |
| Padilla, GM | 1 |
| Shamsuddin, AM | 1 |
| Ullah, A | 1 |
| Chakravarthy, AK | 1 |
| Daniel, FB | 1 |
| DeAngelo, AB | 1 |
| Stober, JA | 1 |
| Pereira, MA | 1 |
| Olson, GR | 1 |
| Calvert, RJ | 1 |
| Klurfeld, DM | 1 |
| Subramaniam, S | 1 |
| Vahouny, GV | 1 |
| Kritchevsky, D | 1 |
| Wilpart, M | 1 |
| Roberfroid, M | 1 |
| O'Dwyer, PJ | 1 |
| McCabe, DP | 1 |
| Sickle-Santanello, BJ | 1 |
| Woltering, EA | 1 |
| Clausen, K | 1 |
| Martin, EW | 1 |
| Reddy, BS | 1 |
| Temple, NJ | 1 |
| Basu, TK | 1 |
| Pence, BC | 2 |
| Buddingh, F | 2 |
| Glickman, LT | 1 |
| Suissa, S | 1 |
| Fleiszer, DM | 1 |
| Trukhanova, LS | 1 |
| Colacchio, TA | 1 |
| Memoli, VA | 1 |
| Abu-Khalaf, M | 1 |
| Hamada, S | 1 |
| Hirayama, R | 1 |
| Matsumura, J | 1 |
| Takagi, Y | 1 |
| Miyanaga, T | 1 |
| Aoki, N | 1 |
| Mishima, Y | 1 |
| Lindenschmidt, RC | 1 |
| Tryka, AF | 1 |
| Goad, ME | 1 |
| Witschi, HP | 1 |
| Kaufmann, P | 1 |
| Mangian, HJ | 1 |
2 reviews available for 1,2-dimethylhydrazine and Body Weight
| Article | Year |
|---|---|
Impact of physical activity on intestinal cancer development in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Mass Index; Body Weight; Carcinogens; Colorectal | 2005 |
Dietary fat and colon cancer: variable results in animal models.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Weight; Cocarcinogenesis; Colonic Neoplasms; Diet | 1986 |
117 other studies available for 1,2-dimethylhydrazine and Body Weight
| Article | Year |
|---|---|
Anti-inflammatory and Antioxidant Effect of Lycoperoside H against the 1,2-Dimethyl Hydrazine (DMH) Induced Colorectal Cancer in Rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Colorectal Neop | 2022 |
Evaluation of membrane-destructive processes in rats with induced carcinogenesis of the colon using the cytostatic vincristine.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Carcinogens; Colonic Neoplasms; Cytosta | 2022 |
Phytic acid improves intestinal mucosal barrier damage and reduces serum levels of proinflammatory cytokines in a 1,2-dimethylhydrazine-induced rat colorectal cancer model.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cadherins; Claudin-1; Colon; Colorectal Neoplasms; Cyto | 2018 |
Chemopreventive effect of Callistemon citrinus (Curtis) Skeels against colon cancer induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Antineoplastic Agents, Phytogenic; Body Weight; | 2019 |
Long-term treatment with Sitagliptin, a dipeptidyl peptidase-4 inhibitor, reduces colon carcinogenesis and reactive oxygen species in 1,2-dimethylhydrazine-induced rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Colonic Neoplasms; Dipeptidyl Peptidase | 2013 |
Modulating effect of d-carvone on 1,2-dimethylhydrazine-induced pre-neoplastic lesions, oxidative stress and biotransforming enzymes, in an experimental model of rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Body Weight; Carcinogenesis; Chemoprevention; C | 2013 |
Modulation of expression of Programmed Death-1 by administration of probiotic Dahi in DMH-induced colorectal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Dimenhydrinate; Probiotics; Rats; Rats, | 2013 |
Probiotic Dahi containing Lactobacillus acidophilus and Bifidobacterium bifidum modulates the formation of aberrant crypt foci, mucin-depleted foci, and cell proliferation on 1,2-dimethylhydrazine-induced colorectal carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Bifidobacterium; Body Weight; Buffaloes; Carcin | 2014 |
Lactobacillus salivarius Ren prevent the early colorectal carcinogenesis in 1, 2-dimethylhydrazine-induced rat model.
Topics: 1,2-Dimethylhydrazine; Animals; Antibiosis; Bacillus; Body Weight; Carcinogenesis; Cell Proliferatio | 2014 |
Cyclooxygenase as a target in chemoprevention by probiotics during 1,2-dimethylhydrazine induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; C | 2015 |
Doxycycline Promotes Carcinogenesis & Metastasis via Chronic Inflammatory Pathway: An In Vivo Approach.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogenesis; Caspase 3; Caspase 9; Cell Proliferatio | 2016 |
Exenatide suppresses 1,2-dimethylhydrazine-induced colon cancer in diabetic mice: Effect on tumor angiogenesis and cell proliferation.
Topics: 1,2-Dimethylhydrazine; Animals; Antigens, CD34; Body Weight; Cell Proliferation; Cisplatin; Colon; C | 2016 |
Morin and Esculetin supplementation modulates c-myc induced energy metabolism and attenuates neoplastic changes in rats challenged with the procarcinogen 1,2 - dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Body Weight; Carcinogenesis; | 2017 |
Effect of hesperetin, a citrus flavonoid, on bacterial enzymes and carcinogen-induced aberrant crypt foci in colon cancer rats: a dose-dependent study.
Topics: 1,2-Dimethylhydrazine; Animals; Bacteria; Body Weight; Carcinogens; Cell Transformation, Neoplastic; | 2008 |
IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Cell Proliferation; Cells, Cultur | 2009 |
Silibinin modulates biotransforming microbial enzymes and prevents 1,2-dimethylhydrazine-induced preneoplastic changes in experimental colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Bacteria; Body Weight; Colon; Colonic Neopl | 2009 |
Effect of Neem (Azadirchta indica) on serum glycoprotein contents of rats administered 1,2 dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Azadirachta; Body Weight; Carcinogens; Colonic Neoplasms; Glycerides | 2009 |
Membrane fluidity and surface changes during initiation of 1,2 dimethylhydrazine-induced colon carcinogenesis: protection by zinc.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colon; Colonic Neoplasms; Diphenylhexatriene; Fluoresce | 2009 |
Effects of lycopene, synbiotic and their association on early biomarkers of rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents, Phytogenic; Bifidobacterium; Biomarkers, Tumo | 2010 |
[Preventive effects of berberine on experimental colon cancer and relationship with cyclooxygenase-2 expression].
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Berberine; Body Weight; Colonic Neoplasms; Cycl | 2010 |
Cancer chemopreventive potential of the Egyptian flaxseed oil in a rat colon carcinogenesis bioassay--implications for its mechanism of action.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; | 2011 |
High fat mixed lipid diet modifies protective effects of exercise on 1,2 dimethylhydrazine induced colon cancer in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Body Weight; Colonic Neoplasms; Diet, High-Fat; Lipid | 2012 |
Influence of gilaburu (Viburnum opulus) juice on 1,2-dimethylhydrazine (DMH)-induced colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Beverages; Body Weight; Colon; Colonic Neoplasms; Fruit; Male; Mice; | 2013 |
Reduction in colon cancer risk by consumption of kava or kava fractions in carcinogen-treated rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms | 2012 |
Effect of thymoquinone on 1,2-dimethyl-hydrazine-induced oxidative stress during initiation and promotion of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Benzoquinones; Body Weight; Carcinogens; Carcinoma; Ce | 2013 |
Probiotics Lactobacillus rhamnosus GG, Lactobacillus acidophilus suppresses DMH-induced procarcinogenic fecal enzymes and preneoplastic aberrant crypt foci in early colon carcinogenesis in Sprague Dawley rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Body Weight; Colonic Neoplasms; Feces; Glucuron | 2013 |
Lack of inhibitory effects of green tea catechins in 1,2-dimetylhydrazine-induced rat intestinal carcinogenesis model: comparison of the different formulations, administration routes and doses.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Carcinogenicity Tests | 2002 |
Different effects of short- and long-chained fructans on large intestinal physiology and carcinogen-induced aberrant crypt foci in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cecum; Cell Division; Colonic Neoplasms; Colony Count, | 2002 |
Effects of high molybdenum intake on 1,2-dimethylhydrazine-induced intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cell Division; Diet; Intestinal Neoplasms; Male; Molybd | 2002 |
Rapid induction of colorectal tumors in rats initiated with 1,2-dimethylhydrazine followed by dextran sodium sulfate treatment.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dextran | 2003 |
Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight | 2003 |
Vanadium inhibits placental glutathione S-transferase (GST-P) positive foci in 1,2-dimethyl hydrazine induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Colonic Neoplasms; | 2003 |
Chromium-containing biomimetic cation triaqua-mu3-oxo-mu-hexapropionatotrichromium(III) inhibits colorectal tumor formation in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Biomimetics; Body Weight; Carcinogens; Cations; Cell Line, Tumor; Ch | 2004 |
Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
Topics: 1,2-Dimethylhydrazine; Age Factors; Aging; Animals; Anticarcinogenic Agents; Benzimidazoles; Body Te | 2005 |
Vanadium inhibits DNA-protein cross-links and ameliorates surface level changes of aberrant crypt foci during 1,2-dimethylhydrazine induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colon; Colonic Neoplasms; Comet Assay; Cytochrome P-450 | 2005 |
Lack of chemopreventive effects of alpha-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Colonic | 2006 |
Chemopreventive potential of zinc in experimentally induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Alkylating Agents; Animals; Anticarcinogenic Agents; An | 2007 |
Chemopreventive effects of nonsteroidal anti-inflammatory drugs in the membrane lipid composition and fluidity parameters of the 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Bo | 2007 |
Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium.
Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Antioxidants; Body Weight; Calcium, Dietary; Cattle; | 2008 |
A new medium-term rat colorectal bioassay applying neoplastic lesions as end points for detection of carcinogenesis modifiers effects with weak or controversial modifiers.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Col | 2008 |
Chronic effects of dietary exposure to amosite and chrysotile asbestos in Syrian golden hamsters.
Topics: 1,2-Dimethylhydrazine; Animals; Asbestos; Asbestos, Amosite; Asbestos, Serpentine; Body Weight; Coca | 1983 |
Chronic effects of dietary exposure to amosite asbestos and tremolite in F344 rats.
Topics: 1,2-Dimethylhydrazine; Animals; Asbestos; Asbestos, Amosite; Asbestos, Amphibole; Body Weight; Cocar | 1983 |
An investigation into the mechanism of co-carcinogenesis of dietary cholesterol during the induction of colon cancer in rats by 1,2 dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cholesterol, Dietary; Colonic Neoplasms; D | 1984 |
BALB/c mice fed milk or beef protein: differences in response to 1,2-dimethylhydrazine carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cattle; Cocarcinogenesis; Colonic Neoplasms; Cytotoxici | 1983 |
Teratogenic assessment of three methylated hydrazine derivatives in the rat.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Dimethylhydrazines; Female; Fetal Resorption; Injection | 1984 |
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating | 1984 |
Inhibition of experimental colorectal cancer by razoxane (ICRF-159).
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Dru | 1984 |
Studies on experimental colon tumorigenesis in rats. 1. Strain differences in incidence, location and tumor types of 1, 2-dimethylhydrazine-induced tumors.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Female; | 1981 |
Effects of small bowel transection, resection, or bypass in 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Feces; Gastroint | 1983 |
Effect of Konjac mannan on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Dimethy | 1983 |
Effect of alterations in the quality and quantity of dietary fat on 1,2-dimethylhydrazine-induced colon tumorigenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; Dietary Fats; Dim | 1983 |
The effects of cholic acid and bile salt binding agents on 1,2-dimethylhydrazine-induced colon carcinogenesis in the rat.
Topics: 1,2-Dimethylhydrazine; Aluminum Hydroxide; Animals; Bile Acids and Salts; Body Weight; Cholestyramin | 1981 |
Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; D | 1994 |
Effect of beta-carotene, sodium ascorbate and cellulose on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Ascorbic Acid; beta Carotene; Body Weight; | 1994 |
Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Diethylnitro | 1994 |
Effect of aspirin on incidence and growth of aberrant crypt foci induced in the rat colon by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Aspirin; Body Weight; Carcinogens; Cell Div | 1994 |
Action of estrogen and adrenocorticoids on adenocarcinoma induction by 1,2-dimethylhydrazine in male rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colon; Colonic Neoplasms; | 1993 |
Effects of green tea catechins in a rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitr | 1993 |
Effects of rice bran hemicellulose on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in Fischer 344 rats.
Topics: 1,2-Dimethylhydrazine; Acids; Animals; Body Weight; Carcinogens; Cecum; Dimethylhydrazines; Hydrogen | 1993 |
Influence of dietary calcium and vitamin D on colon epithelial cell proliferation and 1,2-dimethylhydrazine-induced colon carcinogenesis in rats fed high fat diets.
Topics: 1,2-Dimethylhydrazine; Animals; Autoradiography; Body Weight; Calcifediol; Calcium, Dietary; Carcino | 1993 |
Effect of heat processing and of vegetables and fruit in human diets on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; Dimethylhydrazine | 1993 |
Reduction in formation and growth of 1,2-dimethylhydrazine-induced aberrant crypt foci in rat colon by docosahexaenoic acid.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Colon; Colonic Neoplasms; Dimethylhydrazin | 1993 |
A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Body Weight; Butyrates; Butyric Acid; Carcino | 1996 |
The effect of lactulose on DNA damage induced by DMH in the colon of human flora-associated rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cecum; Colon; Dimethylhydrazines; DNA Dama | 1996 |
Zinc deprivation promotes progression of 1,2-dimethylhydrazine-induced colon tumors but reduces malignant invasion in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma in Situ; Collage | 1997 |
Interaction of dietary fat with a vegetables-fruit mixture on 1,2-dimethylhydrazine-induced colorectal cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogens; Colorectal Neopla | 1997 |
Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats.
Topics: 1,2-Dimethylhydrazine; Animals; Bacteria; Biomarkers; Body Weight; Colon; Colonic Diseases; Colonic | 1997 |
Melatonin and colon carcinogenesis: I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Colonic Neopla | 1997 |
The nonfermentable dietary fiber lignin alters putative colon cancer risk factors but does not protect against DMH-induced colon cancer in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Bile Acids and Salts; Body Weight; Carcinogens; Colo | 1997 |
Inhibition of development of N,N'-dimethylhydrazine-induced rat colonic aberrant crypt foci by pre, post and simultaneous treatments with 24R,25-dihydroxyvitamin D3.
Topics: 1,2-Dimethylhydrazine; 24,25-Dihydroxyvitamin D 3; Animals; Anticarcinogenic Agents; Body Weight; Ca | 1997 |
Dietary maltitol decreases the incidence of 1,2-dimethylhydrazine-induced cecum and proximal colon tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cecal Neoplasms; Cecum; Colonic Neoplasms; | 1998 |
Dietary wheat bran modulates proliferating cell nuclear antigen-labeling index of the rat colorectum after treatment with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colon; Dietary Fiber; Immunohistochemistry; Male; Proli | 1997 |
Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carotenoids; Chemoprevention; Colonic Neoplasms; Diethy | 1997 |
Microvascular endothelium dysfunction in rats bearing 1,2-dimethylhydrazine-induced colon tumors.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Capillary Permeability; Carcinogens; Cell Adhesion; Col | 1999 |
Inhibitory effects of freeze-dried milk fermented by selected Lactobacillus bulgaricus strains on carcinogenesis induced by 1,2-dimethylhydrazine in rats and by diethylnitrosamine in hamsters.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Biological Therapy; Body Weight; Carcinogen | 1999 |
A probiotic strain of L. acidophilus reduces DMH-induced large intestinal tumors in male Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Fatty A | 1999 |
Inhibitory effect of synthetic interferon inductor Cycloferone on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Acridines; Adenocarcinoma; Animals; Anticarcinogenic Agents; Body Weight; Car | 2000 |
Lymphoproliferative response and T lymphocyte subsets in a medium-term multi-organ bioassay for carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Alkylating Agents; Animals; Body Weight; Butylhydroxyb | 2000 |
Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition.
Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Body Weight; Butyr | 2000 |
Blood polyamine levels after oral ornithine load, a diagnostic marker of hyperproliferative premalignant and malignant stages in a model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Biotransformation; Body | 2000 |
The effect of dietary lactulose on experimental large bowel cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms | 1980 |
A protective role of dietary vitamin D3 in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Bromodeoxyuridine; Calcifediol; Calcitr | 2000 |
Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Butylhydroxybutylnitr | 2001 |
Green tea catechins enhance tumor development in the colon without effects in the lung or thyroid after pretreatment with 1,2-Dimethylhydrazine or 2,2'-dihydroxy-di-n-propylnitrosamine in male F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Catechin; Colonic Neop | 2001 |
A buckwheat protein product suppresses 1,2-dimethylhydrazine-induced colon carcinogenesis in rats by reducing cell proliferation.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cell Division; Colonic Neoplasms; Dietary | 2001 |
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Administration, Oral; Anim | 2001 |
High fat diet enhances colonic cell proliferation and carcinogenesis in rats by elevating serum leptin.
Topics: 1,2-Dimethylhydrazine; Adipose Tissue; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Di | 2001 |
Prevention of development of N,N'-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Body Weight; Cell Extracts; C | 2002 |
The effect of vagotomy and pyloroplasty on colorectal tumor induction in the rat.
Topics: 1,2-Dimethylhydrazine; Analysis of Variance; Animals; Body Weight; Carcinogens; Colorectal Neoplasms | 1992 |
The influence of dietary vitamin E and calcium status on intestinal tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Calcium, Dietary; Dietary Fats; Dimethylhydrazines; Ene | 1992 |
The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Body Weight; Carcinogens; Colon; Dimet | 1991 |
Effect of dietary calcium on colon carcinogenesis induced by a single injection of 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Autoradiography; Body Weight; Bone Density; Calcium, Dietary; Carcin | 1991 |
Dietary protein and chronic toxicity of 1,2-dimethylhydrazine fed to mice.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Adrenal Glands; Animals; Body Weight; Carcinogens; Diet | 1991 |
Effect of disulfiram on 1,2-dimethylhydrazine- and azoxymethane-induced aberrant crypt foci.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Di | 1991 |
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; alph | 1990 |
Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Colonic Neoplasms; | 1990 |
Vanadate supplements and 1,2-dimethylhydrazine induced colon cancer in mice: increased thymidine incorporation without enhanced carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazines | 1986 |
Suppression of a a carcinogen (1,2-dimethylhydrazine dihydrochloride)-induced increase in mitotic activity in the colonic crypts of rats by addition of dietary cellulose.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cellulose; Colon; Dietary Fiber; Dimethylhydrazines; En | 1989 |
Inositol and inositol hexaphosphate suppress cell proliferation and tumor formation in CD-1 mice.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carcinogens; Cell Division; Dimethylhydrazines; Inosito | 1989 |
Chloroform inhibition of 1,2-dimethylhydrazine-induced gastrointestinal tract tumors in the Fisher 344 rat.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Body Weight; Chloroform; Dimethylhydrazines; Gastrointestin | 1989 |
Reduction of colonic carcinogenesis by wheat bran independent of fecal bile acid concentration.
Topics: 1,2-Dimethylhydrazine; Animals; Bile Acids and Salts; Body Weight; Colonic Neoplasms; Dietary Fiber; | 1987 |
Intestinal carcinogenesis and dietary fibers: the influence of cellulose or Fybogel chronically given after exposure to DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Bicarbonates; Body Weight; Cellulose; Citrates; Citric Acid; Colonic | 1987 |
Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethyl Sulfoxide; Dimethylhydrazin | 1988 |
Effect of different levels of dietary corn oil and lard during the initiation phase of colon carcinogenesis in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Azoxymethane; Bile Acids and Salts; Body Weight; Col | 1986 |
Selenium and cabbage and colon carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Animals; Body Weight; Brassica; Colonic Neoplasms; D | 1987 |
Co-carcinogenic effect of carbon black ingestion with dietary fat on the development of colon tumors in rats.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Body Weight; Carbon; Carcinogens; Colonic Neop | 1987 |
Proliferative characteristics of chronic crypt cells in C57BL/6J and A/J mice as predictors of subsequent tumor formation.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Cell Division; Colon; Colonic Neoplasms; Dimethylhydraz | 1987 |
[Effect of ascorbic acid on the induction of uterine sarcomas in mice].
Topics: 1,2-Dimethylhydrazine; Animals; Ascorbic Acid; Body Weight; Dimethylhydrazines; Estradiol; Estrogen | 1987 |
Effect of colon tumor development and dietary fat on the immune system of rats treated with DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Cytotoxicity, Immunologic; Dietary F | 1986 |
Chemoprevention of colorectal neoplasms. Ascorbic acid and beta-carotene.
Topics: 1,2-Dimethylhydrazine; Animals; Ascorbic Acid; beta Carotene; Body Weight; Carotenoids; Colonic Neop | 1986 |
Effects of feeding regimen on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Dimethylhydrazines; Eating; Intestinal Neoplasms; Male; | 1985 |
Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Body Weight; Carcinoma, Squamous Cell; Dime | 1985 |
Longer survival and fewer metastases by levamisole and tegafur in 1, 2-dimethylhydrazine-induced murine colonic cancers.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Colonic | 1985 |
The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylated Hydroxytoluene; Carcinogens; Colonic Neoplasm | 1986 |
Interaction of dietary fat and route of carcinogen administration on 1,2-dimethylhydrazine-induced colon tumorigenesis in rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Colonic | 1985 |
Effect of dietary selenium deficiency on incidence and size of 1,2-dimethylhydrazine-induced colon tumors in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Diet; Dimethylhydrazines; Male; Rats | 1985 |
Plasma amino acids and excretion of protein end products by mice fed 10 or 40% soybean protein diets with or without dietary benzo[a]pyrene or 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Amino Acids; Animals; Benzo(a)pyrene; Body Weight; Dietary Proteins; Dimethyl | 1985 |