1,2-dimethylhydrazine has been researched along with Bilateral Wilms Tumor in 4 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatments were begun 8 days post-operative and 17 days later, the single dosage of DMH as in the above was injected." | 1.29 | Tumors produced in rats with a single dosage of 1,2-dimethylhydrazine. ( Amir-Mokri, E; Brown, ME; Gershbein, LL; Rezai, VK, 1993) |
| "Nephroblastomas were induced at an early age in two of six cynomolgus monkeys by prenatal exposure to 1,2-dimethylhydrazine." | 1.28 | Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine. ( Beniashvili, DS, 1989) |
| "This pathological resemblance to human nephroblastoma suggests the possibility of using dimethylhydrazine-induced renal tumours as a model of Wilms' tumour." | 1.27 | Induction of nephroblastoma-like renal tumours in rats by a single dose of 1,2-dimethylhydrazine. ( Cruse, JP; Lewin, MR; Sadrudin, AA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gershbein, LL | 1 |
| Amir-Mokri, E | 1 |
| Rezai, VK | 1 |
| Brown, ME | 1 |
| Beniashvili, DS | 1 |
| Beniashvili, DSh | 1 |
| Sadrudin, AA | 1 |
| Lewin, MR | 1 |
| Cruse, JP | 1 |
4 other studies available for 1,2-dimethylhydrazine and Bilateral Wilms Tumor
| Article | Year |
|---|---|
Tumors produced in rats with a single dosage of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1993 |
Induction of renal tumors in cynomolgus monkeys (Macaca fascicularis) by prenatal exposure to 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney Neoplasms; Macaca fa | 1989 |
[Induction of renal tumors in monkeys as a result of probable prenatal effects of 1,2-dimethylhydrazine].
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Kidney; Kidney Neoplasms; M | 1989 |
Induction of nephroblastoma-like renal tumours in rats by a single dose of 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Disease Models, Animal; Female; Kid | 1985 |