1,2-dimethylhydrazine has been researched along with Anus Neoplasms in 3 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Anus Neoplasms: Tumors or cancer of the ANAL CANAL.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The histogenesis of perianal squamous cell carcinomas induced by subcutaneous and intraperitoneal injection of 1,2-dimethylhydrazine dihydrochloride (DMH) and painting of methylazoxymethanol (MAM)-acetate on the anal region was investigated in 212 female BALB/c mice." | 1.26 | Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis. ( Furuya, K; Izumi, K; Kawaura, A; Kumagai, H; Otsuka, H, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ird, EA | 1 |
| Smirnova, IO | 1 |
| Kumagai, H | 1 |
| Kawaura, A | 1 |
| Furuya, K | 1 |
| Izumi, K | 1 |
| Otsuka, H | 1 |
| Kingsnorth, AN | 1 |
| Abu-Khalaf, M | 1 |
| Ross, JS | 1 |
| Malt, RA | 1 |
3 other studies available for 1,2-dimethylhydrazine and Anus Neoplasms
| Article | Year |
|---|---|
[Tumors induced by 1,2-dimethylhydrazine in hybrid mice with the pituitary gland transplanted in the kidney].
Topics: 1,2-Dimethylhydrazine; Animals; Anus Neoplasms; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; | 1983 |
Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Azo Compounds; Carcinogens; Carcinoma, Squa | 1982 |
Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Body Weight; Carcinoma, Squamous Cell; Dime | 1985 |