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1,2-dimethylhydrazine and Anus Neoplasms

1,2-dimethylhydrazine has been researched along with Anus Neoplasms in 3 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Anus Neoplasms: Tumors or cancer of the ANAL CANAL.

Research Excerpts

ExcerptRelevanceReference
"The histogenesis of perianal squamous cell carcinomas induced by subcutaneous and intraperitoneal injection of 1,2-dimethylhydrazine dihydrochloride (DMH) and painting of methylazoxymethanol (MAM)-acetate on the anal region was investigated in 212 female BALB/c mice."1.26Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis. ( Furuya, K; Izumi, K; Kawaura, A; Kumagai, H; Otsuka, H, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ird, EA1
Smirnova, IO1
Kumagai, H1
Kawaura, A1
Furuya, K1
Izumi, K1
Otsuka, H1
Kingsnorth, AN1
Abu-Khalaf, M1
Ross, JS1
Malt, RA1

Other Studies

3 other studies available for 1,2-dimethylhydrazine and Anus Neoplasms

ArticleYear
[Tumors induced by 1,2-dimethylhydrazine in hybrid mice with the pituitary gland transplanted in the kidney].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:10

    Topics: 1,2-Dimethylhydrazine; Animals; Anus Neoplasms; Carcinogens; Colonic Neoplasms; Dimethylhydrazines;

1983
Perianal lesions of BALB/c mice induced by 1,2-dimethylhydrazine dihydrochloride and methylazoxymethanol-acetate: their classification and histogenesis.
    Gan, 1982, Volume: 73, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Azo Compounds; Carcinogens; Carcinoma, Squa

1982
Potentiation of 1,2-dimethylhydrazine-induced anal carcinoma by epidermal growth factor in mice.
    Surgery, 1985, Volume: 97, Issue:6

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Anus Neoplasms; Body Weight; Carcinoma, Squamous Cell; Dime

1985