1,2-dimethylhydrazine has been researched along with Angiosarcoma in 9 studies
1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
Excerpt | Relevance | Reference |
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"CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 7.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
"Pararenal angiosarcomas appear in CBA male mice treated with 1,2-dimethylhydrazine (DMH)." | 3.67 | [Effect of sex hormones on the induction of renal capsule angiosarcomas in mice]. ( Chemeris, GIu, 1989) |
"CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas." | 3.67 | Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985) |
"Rats of 3 inbred strains (DA, HS and AS2) were dosed with 1,2-dimethylhydrazine 2HCl (DMH) or saline by gavage weekly for 10 wk." | 1.26 | The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine. ( Gavin, JB; Herdson, PB; Teague, CA, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (77.78) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (22.22) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Morozova, OV | 1 |
Trukhanova, LS | 1 |
Turusov, VS | 5 |
Teague, CA | 1 |
Gavin, JB | 1 |
Herdson, PB | 1 |
Sato, N | 1 |
Kaku, T | 1 |
Dempo, K | 1 |
Kikuchi, K | 1 |
Chemeris, GIu | 2 |
Colussi, C | 1 |
Fiumicino, S | 1 |
Giuliani, A | 1 |
Rosini, S | 1 |
Musiani, P | 1 |
MacrÃ, C | 1 |
Potten, CS | 1 |
Crescenzi, M | 1 |
Bignami, M | 1 |
Smirnova, IO | 1 |
Chemeris, GY | 1 |
Parfenov, YD | 1 |
9 other studies available for 1,2-dimethylhydrazine and Angiosarcoma
Article | Year |
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[Influence of dichlorodiphenyldichloroethylene on 1,2 dimethylhydrazine-induced androgen-dependent renal capsule angiosarcoma development].
Topics: 1,2-Dimethylhydrazine; Androgen Antagonists; Androgens; Animals; Carcinogens; Dichlorodiphenyl Dichl | 2008 |
The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Dimet | 1981 |
The relationship of colonic carcinogenesis and hepatic vascular tumors induced by subcutaneously injected-1,2-dimethylhydrazine dihydrochloride in specific pathogen free mice.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Germ-Fre | 1984 |
Role of host factors in carcinogenesis induced in mice by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Hemangiosarcoma; Hemorrhage | 1983 |
[Effect of castration and mouse strain on 1, 2-dimethylhydrazine induction of pararenal angiosarcomas and kidney adenomas].
Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Castration; Dimethylhydrazines; Hemangiosarcoma; Kidney Neo | 1982 |
1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alkylating Agents; Animals; Apoptosis; Base Pair Mismatch; Ca | 2001 |
[Effect of sex hormones on the induction of renal capsule angiosarcomas in mice].
Topics: 1,2-Dimethylhydrazine; Animals; Castration; Dimethylhydrazines; Drug Interactions; Estradiol; Female | 1989 |
[Modifying action of neonatal androgenization on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA-strain mice].
Topics: 1,2-Dimethylhydrazine; Animals; Animals, Newborn; Dimethylhydrazines; Hemangiosarcoma; Intestinal Ne | 1985 |
Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Adenoma; Androgens; Animals; Carcinogens; Castration; Colonic Neoplasms; Dime | 1985 |