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1,2-dimethylhydrazine and Angiosarcoma

1,2-dimethylhydrazine has been researched along with Angiosarcoma in 9 studies

1,2-Dimethylhydrazine: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
1,2-dimethylhydrazine : A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.

Research Excerpts

ExcerptRelevanceReference
"CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas."7.67Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985)
"Pararenal angiosarcomas appear in CBA male mice treated with 1,2-dimethylhydrazine (DMH)."3.67[Effect of sex hormones on the induction of renal capsule angiosarcomas in mice]. ( Chemeris, GIu, 1989)
"CBA male mice treated with 1,2-dimethylhydrazine (DMH) developed high incidence (up to 97%) of pararenal angiosarcomas."3.67Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis. ( Chemeris, GY; Parfenov, YD; Turusov, VS, 1985)
"Rats of 3 inbred strains (DA, HS and AS2) were dosed with 1,2-dimethylhydrazine 2HCl (DMH) or saline by gavage weekly for 10 wk."1.26The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine. ( Gavin, JB; Herdson, PB; Teague, CA, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morozova, OV1
Trukhanova, LS1
Turusov, VS5
Teague, CA1
Gavin, JB1
Herdson, PB1
Sato, N1
Kaku, T1
Dempo, K1
Kikuchi, K1
Chemeris, GIu2
Colussi, C1
Fiumicino, S1
Giuliani, A1
Rosini, S1
Musiani, P1
Macrí, C1
Potten, CS1
Crescenzi, M1
Bignami, M1
Smirnova, IO1
Chemeris, GY1
Parfenov, YD1

Other Studies

9 other studies available for 1,2-dimethylhydrazine and Angiosarcoma

ArticleYear
[Influence of dichlorodiphenyldichloroethylene on 1,2 dimethylhydrazine-induced androgen-dependent renal capsule angiosarcoma development].
    Voprosy onkologii, 2008, Volume: 54, Issue:3

    Topics: 1,2-Dimethylhydrazine; Androgen Antagonists; Androgens; Animals; Carcinogens; Dichlorodiphenyl Dichl

2008
The response of three inbred strains of rat to the carcinogen 1,2-dimethylhydrazine.
    Pathology, 1981, Volume: 13, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Dimet

1981
The relationship of colonic carcinogenesis and hepatic vascular tumors induced by subcutaneously injected-1,2-dimethylhydrazine dihydrochloride in specific pathogen free mice.
    Cancer letters, 1984, Volume: 24, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Germ-Fre

1984
Role of host factors in carcinogenesis induced in mice by 1,2-dimethylhydrazine.
    IARC scientific publications, 1983, Issue:51

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Dimethylhydrazines; Female; Hemangiosarcoma; Hemorrhage

1983
[Effect of castration and mouse strain on 1, 2-dimethylhydrazine induction of pararenal angiosarcomas and kidney adenomas].
    Voprosy onkologii, 1982, Volume: 28, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenoma; Animals; Castration; Dimethylhydrazines; Hemangiosarcoma; Kidney Neo

1982
1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice.
    Journal of the National Cancer Institute, 2001, Oct-17, Volume: 93, Issue:20

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Alkylating Agents; Animals; Apoptosis; Base Pair Mismatch; Ca

2001
[Effect of sex hormones on the induction of renal capsule angiosarcomas in mice].
    Eksperimental'naia onkologiia, 1989, Volume: 11, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Castration; Dimethylhydrazines; Drug Interactions; Estradiol; Female

1989
[Modifying action of neonatal androgenization on 1,2-dimethylhydrazine-induced carcinogenesis in male CBA-strain mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Animals, Newborn; Dimethylhydrazines; Hemangiosarcoma; Intestinal Ne

1985
Pararenal angiosarcoma induced in male mice by 1,2-dimethylhydrazine--a model for studying the role of androgens in chemical carcinogenesis.
    Carcinogenesis, 1985, Volume: 6, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenoma; Androgens; Animals; Carcinogens; Castration; Colonic Neoplasms; Dime

1985